Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Supratik, Das"'
Autor:
Hilal Ahmad Parray, Naveen Narayanan, Sonal Garg, Zaigham Abbas Rizvi, Tripti Shrivastava, Sachin Kushwaha, Janmejay Singh, Praveenkumar Murugavelu, Anbalagan Anantharaj, Farha Mehdi, Nisha Raj, Shivam Singh, Jyotsna Dandotiya, Asha Lukose, Deepti Jamwal, Sandeep Kumar, Adarsh K Chiranjivi, Samridhi Dhyani, Nitesh Mishra, Sanjeev Kumar, Kamini Jakhar, Sudipta Sonar, Anil Kumar Panchal, Manas Ranjan Tripathy, Shirlie Roy Chowdhury, Shubbir Ahmed, Sweety Samal, Shailendra Mani, Sankar Bhattacharyya, Supratik Das, Subrata Sinha, Kalpana Luthra, Gaurav Batra, Devinder Sehgal, Guruprasad R Medigeshi, Chandresh Sharma, Amit Awasthi, Pramod Kumar Garg, Deepak T Nair, Rajesh Kumar
Publikováno v:
PLoS Pathogens, Vol 18, Iss 12, p e1010994 (2022)
The emergence of new variants of SARS-CoV-2 necessitates unremitting efforts to discover novel therapeutic monoclonal antibodies (mAbs). Here, we report an extremely potent mAb named P4A2 that can neutralize all the circulating variants of concern (V
Externí odkaz:
https://doaj.org/article/3ba087963a9548d5823331f44d97566f
Publikováno v:
MethodsX, Vol 6, Iss , Pp 837-849 (2019)
An ideal vaccine against HIV-1 will specifically elicit bNAbs (broadly neutralizing antibodies) which can cross-neutralize a wide spectrum of circulating viral strains belonging to different clades. The current paradigm for developing such a vaccine
Externí odkaz:
https://doaj.org/article/52c15fa8d27e42eda7c78d28d2a3a79b
Publikováno v:
Therapeutic Advances in Vaccines and Immunotherapy, Vol 8 (2020)
The enormous diversity of HIV-1 is a significant impediment in selecting envelopes (Envs) that can be suitable for designing vaccine immunogens. While tremendous progress has been made in developing soluble, trimeric, native-like Env proteins, those
Externí odkaz:
https://doaj.org/article/7f5276a3a5b045ba87fcbfb035816ea3
Autor:
Sweety Samal, Supratik Das, Saikat Boliar, Huma Qureshi, Tripti Shrivastava, Naresh Kumar, Sandeep Goswami, Manish Bansal, Bimal K. Chakrabarti
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-19 (2018)
Abstract Background HIV-1 Env gp160 is cleaved to form gp120 and gp41 and the functional HIV-1 Env is a trimer of non-covalently associated heterodimeric subunits, gp120 and gp41. The cleaved, native, trimeric form of Envs expose only broadly neutral
Externí odkaz:
https://doaj.org/article/9c2ce722125a482ea4665992252727bf
Autor:
Adarsh Kumar, Chiranjivi, Dilip, Kumar, Rajesh, Kumar, Hilal Ahmad, Parray, Shubbir, Ahmed, Chandra Sekhar, Kumar, Tripti, Shrivastava, Manidipa, Banerjee, B V Venkataram, Prasad, Supratik, Das
Publikováno v:
International Journal of Biological Macromolecules. 217:19-26
Dengue virus is transmitted by Aedes mosquitoes and dengue is endemic in many regions of the world. Severe dengue results in complications that may lead to death. Although some vaccine candidates are in clinical trials and one vaccine Dengvaxia, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd7751e771f38544389f32035133585
https://doi.org/10.1016/j.ijbiomac.2022.07.028
https://doi.org/10.1016/j.ijbiomac.2022.07.028
Autor:
Supratik Das
Publikováno v:
Molecular and Cellular Biochemistry. 477:2415-2431
Translation initiation is the first step in three essential processes leading to protein synthesis. It is carried out by proteins called translation initiation factors and ribosomes on the mRNA. One of the critical translation initiation factors in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5646d3311ef6eecb75ab92208abe1d61
https://doi.org/10.1007/s11010-022-04464-7
https://doi.org/10.1007/s11010-022-04464-7
Autor:
Supratik Das, Hilal Ahmad Parray, Adarsh Kumar Chiranjivi, Manish Bansal, Deepak Kumar Rathore, Rajesh Kumar, Sweety Samal
Efficiently cleaved HIV-1 Envs are the closest mimics of functional Envs as they specifically expose only bNAb (broadly neutralizing antibody) epitopes and not non-neutralizing ones, making them suitable for developing vaccine immunogens. We have pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d46c7895e12f637dec563e7a5e01c46
https://doi.org/10.21203/rs.3.rs-2245790/v1
https://doi.org/10.21203/rs.3.rs-2245790/v1
Autor:
Anica Dadwal, Supratik Das
Initiation of translation is the first of the three obligatory steps required for protein synthesis and is carried out by a large number of protein factors called initiation factors in conjunction with ribosomes. One of the key conserved protein fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16b4f3364af98231a22507403951e266
https://doi.org/10.21203/rs.3.rs-2040047/v1
https://doi.org/10.21203/rs.3.rs-2040047/v1
Autor:
Rajesh Kumar, Hilal Parray, Naveen Narayan, Sonal Garg, Zaigham Abbas Rizvi, Tripti Shrivastava, Sachin Kushwaha, Janmejay Singh, Praveenkumar Murugavelu, Anbalagan Anantharaj, Farha Mehdi, Nisha Raj, Shivam Singh, Jyotsna Dandotiya, Asha Lukose, Deepti Jamwal, Sandeep Kumar, Adarsh Chiranjivi, Samridhi Dhyani, Nitesh Mishra, Kamini Jakhar, Sudipta Sonar, Shirlie Chowdhury, Anil Panchal, Manas Tripathy, Shubbir Ahmed, Sweety Samal, Shailendra Mani, Sankar Bhattacharyya, Supratik Das, Subrata Sinha, Gaurav Batra, Devinder Sehgal, Guruprasad Medigeshi, Chandresh Sharma, Amit Awasthi, Pramod Garg, Deepak Nair
The emergence of new variants of SARS-CoV-2 necessitates unremitting efforts to discover novel therapeutic mAbs. Here, we report an extremely potent mAb named P4A2 that can neutralize all the circulating variants of concerns (VOCs) with high efficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90321952534c9479c085578e48e99bd6
https://doi.org/10.21203/rs.3.rs-1431974/v1
https://doi.org/10.21203/rs.3.rs-1431974/v1
Autor:
Supratik Das
Publikováno v:
Molecular and Cellular Biochemistry. 476:1037-1049
Protein translation leading to polypeptide synthesis involves three distinct events, namely, initiation, elongation, and termination. Translation initiation is a multi-step process that is carried out by ribosomes on the mRNA with the assistance of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2342e92ff46bf419d6ade194efb58f
https://doi.org/10.1007/s11010-020-03970-w
https://doi.org/10.1007/s11010-020-03970-w