Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Supojjanee Sansook"'
Autor:
Supojjanee Sansook, Ella Lineham, Storm Hassell-Hart, Graham J. Tizzard, Simon J. Coles, John Spencer, Simon J. Morley
Publikováno v:
Molecules, Vol 23, Iss 9, p 2126 (2018)
Two novel ferrocene-containing compounds based upon a known MNK1/2 kinase (MAPK-interacting kinase) inhibitor have been synthesized. The compounds were designed to use the unique shape of ferrocene to exploit a large hydrophobic pocket in MNK1/2 that
Externí odkaz:
https://doaj.org/article/3600d182947f4ebdb52c503ba1194c8b
Crystal structure of [3-amino-2-(phenyldiazenyl)pyridine]chlorido(η6-p-cymene)ruthenium(II) chloride
Autor:
Kanidtha Hansongnern, Supojjanee Sansook, Thassani Romin, Arunpatcha Nimthong Roldan, Chaveng Pakawatchai
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 71, Iss 10, Pp m185-m186 (2015)
The title compound, [RuCl(C10H14)(C11H10N4)]Cl is an RuII complex in which an η6-p-cymene ligand, two N atoms of 3-amino-2-(phenylazo)pyridine and one Cl ion form a piano-stool coordination environment around the metal ion. In the crystal structure,
Externí odkaz:
https://doaj.org/article/9f3974d5d79140ffa63fe13c7077a5c1
Autor:
Fabio Caradonna, Supojjanee Sansook, Claudio Luparello, Ilenia Cruciata, Storm Hassell-Hart, John Spencer, Dalia Maria Lucia Asaro
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 4
International Journal of Molecular Sciences, Vol 20, Iss 4, p 804 (2019)
Volume 20
Issue 4
International Journal of Molecular Sciences, Vol 20, Iss 4, p 804 (2019)
We examined the effects of the ferrocene-based histone deacetylase-3 inhibitor Pojamide (N1-(2-aminophenyl)-N8-ferrocenyloctanediamide) and its two derivatives N1-(2-aminophenyl)-N6-ferrocenyladipamide and N1-(2-aminophenyl)-N8-ferroceniumoctanediami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b00e2ab6ac4187f5ca7b9106f344be
Autor:
Wei Tuo, Supojjanee Sansook, John Spencer, Aurélien Tourteau, Graham J. Tizzard, Lucas Lemaire, Amélie Barczyk, Régis Millet, Xavier Dezitter, Simon J. Coles, Frédérique Klupsch, Natascha Leleu-Chavain
Publikováno v:
Organometallics
Organometallics, 2016, 35 (19), pp.3361-3368. ⟨10.1021/acs.organomet.6b00575⟩
Organometallics, American Chemical Society, 2016, 35 (19), pp.3361-3368. ⟨10.1021/acs.organomet.6b00575⟩
Organometallics, 2016, 35 (19), pp.3361-3368. ⟨10.1021/acs.organomet.6b00575⟩
Organometallics, American Chemical Society, 2016, 35 (19), pp.3361-3368. ⟨10.1021/acs.organomet.6b00575⟩
International audience; A small library of ferrocene-containing amides has been synthesized using standard amide coupling chemistry with ferrocenylamine. Ferrocene analogues of known bioactive adamantylamides were shown to be effective cannabinoid re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98dc73c0226109dd143150e6615bc4aa
https://doi.org/10.1021/acs.organomet.6b00575
https://doi.org/10.1021/acs.organomet.6b00575
Autor:
Wei Tuo, Xavier Dezitter, Natascha Leleu-Chavain, Supojjanee Sansook, Mélanie Bollier, Régis Millet, Amélie Barczyk, Graham J. Tizzard, Amaury Farce, Frederique Klupsch, Simon J. Coles, John Spencer
Publikováno v:
Future Medicinal Chemistry
Future Medicinal Chemistry, Future Science, 2018, 10 (6), pp.631-638. ⟨10.4155/fmc-2017-0200⟩
Future Medicinal Chemistry, 2018, 10 (6), pp.631-638. ⟨10.4155/fmc-2017-0200⟩
Future Medicinal Chemistry, Future Science, 2018, 10 (6), pp.631-638. ⟨10.4155/fmc-2017-0200⟩
Future Medicinal Chemistry, 2018, 10 (6), pp.631-638. ⟨10.4155/fmc-2017-0200⟩
Ferrocene analogs of known fatty acid amide hydrolase inhibitors and CB2 ligands have been synthesized and characterized spectroscopically and crystallographically. The resulting bio-organometallic isoxazoles were assayed for their effects on CB1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15a06f93899aaa9a73858ec9e18bdc8
https://hal.archives-ouvertes.fr/hal-03328284
https://hal.archives-ouvertes.fr/hal-03328284
Autor:
Ilenia Cruciata, Mariangela Librizzi, Fabio Caradonna, Janusz Dębski, Supojjanee Sansook, Michał Dadlez, John Spencer, Claudio Luparello
Jay Amin Hydroxamic Acid (JAHA; N8-ferrocenylN1-hydroxy-octanediamide) is a ferrocene-containing analogue of the histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA). JAHA’s cytotoxic activity on MDA-MB231 triple negative br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::309592320b789746d76f6c68771c649a
http://hdl.handle.net/10447/250520
http://hdl.handle.net/10447/250520
Autor:
Nikolaos Tsoureas, Simon J. Coles, Graham J. Tizzard, Rhiannon N. Jones, Thomas G. Scott, James E. Bradner, Cory A. Ocasio, Peter Coxhead, James Spencer, Justin M. Roberts, Supojjanee Sansook, Helfrid Hochegger, Matthew Guille
Publikováno v:
Ocasio, C A, Sansook, S, Jones, R, Roberts, J M, Scott, T G, Tsoureas, N, Coxhead, P, Guille, M, Tizzard, G J, Coles, S J, Hochegger, H, Bradner, J E & Spencer, J 2017, ' Pojamide : an HDAC3-selective ferrocene analogue with remarkably enhanced redox-triggered ferrocenium activity in cells ', Organometallics . https://doi.org/10.1021/acs.organomet.7b00437
A ferrocene containing o-aminoanilide, N1-(2-aminophenyl)-N8-ferrocenyloctanediamide (2b, Pojamide) displayed nanomolar potency vs HDAC3. In comparison to RGFP966, a potent and selective HDAC3 inhibitor, Pojamide displayed superior activity in HCT116
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3740e6c7b657bbf89c178144ecc0e6e
https://eprints.soton.ac.uk/413525/
https://eprints.soton.ac.uk/413525/
Autor:
John Spencer, Mariangela Librizzi, Janusz Debski, Claudio Luparello, Fabio Caradonna, Supojjanee Sansook, Ilenia Cruciata, Michal Dadlez
Jay Amin Hydroxamic Acid (JAHA; N8-ferrocenylN1-hydroxy-octanediamide) is a ferrocene-containing analogue of the histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA). JAHA’s cytotoxic activity on MDA-MB231 triple negative br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f795e059be6d7802ff43a2ddfe6e2b
https://hdl.handle.net/10447/250516
https://hdl.handle.net/10447/250516
Autor:
Natascha Leleu-Chavain, Wei Tuo, Régis Millet, Supojjanee Sansook, John Spencer, Philippe Chavatte
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 2016, 60 (1), pp.4-46. ⟨10.1021/acs.jmedchem.6b00538⟩
Journal of Medicinal Chemistry, American Chemical Society, 2016, 60 (1), pp.4-46. ⟨10.1021/acs.jmedchem.6b00538⟩
ResearcherID
Journal of Medicinal Chemistry, 2016, 60 (1), pp.4-46. ⟨10.1021/acs.jmedchem.6b00538⟩
Journal of Medicinal Chemistry, American Chemical Society, 2016, 60 (1), pp.4-46. ⟨10.1021/acs.jmedchem.6b00538⟩
ResearcherID
International audience; Fatty acid ethanolamides (FAEs) and endocannabinoids (ECs) have been shown to alleviate pain and inflammation, regulate motility and appetite, and produce anticancer, anxiolytic, and neuroprotective efficacies via cannabinoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1338aa890cdd5d9e41c0631c4c6a3f
https://hal.science/hal-03328285
https://hal.science/hal-03328285
Autor:
Graham J. Tizzard, John Spencer, Ella Lineham, Simon J. Morley, Storm Hassell-Hart, Simon J. Coles, Supojjanee Sansook
Publikováno v:
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Volume 23
Issue 9
Molecules, Vol 23, Iss 9, p 2126 (2018)
Molecules
Volume 23
Issue 9
Molecules, Vol 23, Iss 9, p 2126 (2018)
Two novel ferrocene-containing compounds based upon a known MNK1/2 kinase (MAPK-interacting kinase) inhibitor have been synthesized. The compounds were designed to use the unique shape of ferrocene to exploit a large hydrophobic pocket in MNK1/2 that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585ab6204fe5428a6989391d487a63bf
https://doi.org/10.3390/molecules23092126
https://doi.org/10.3390/molecules23092126