Zobrazeno 1 - 10
of 343
pro vyhledávání: '"Suplatast tosilate"'
Autor:
Yuru Chen, Jiazheng Sun, Yachan Luo, Jiazhou Liu, Xiaoyu Wang, Rui Feng, Jing Huang, Huimin Du, Qin Li, Jinxiang Tan, Guosheng Ren, Xiaoyi Wang, Hongzhong Li
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Breast cancer is a complex disease with a highly immunosuppressive tumor microenvironment, and has limited clinical response to immune checkpoint blockade (ICB) therapy. T-helper 2 (Th2) cells, an important component of the tumor
Externí odkaz:
https://doaj.org/article/d02cb9ad87a24ed39ed6f11bb7a324c5
Akademický článek
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Autor:
Hiroyuki Mizuguchi, Naoki Orimoto, Takuya Kadota, Takahiro Kominami, Asish K. Das, Akiho Sawada, Misaki Tamada, Kohei Miyagi, Tsubasa Adachi, Mayumi Matsumoto, Tomoya Kosaka, Yoshiaki Kitamura, Noriaki Takeda, Hiroyuki Fukui
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 3, Pp 151-158 (2016)
Histamine H1 receptor (H1R) gene is upregulated in patients with pollinosis; its expression level is highly correlated with the nasal symptom severity. Antihistamines are widely used as allergy treatments because they inhibit histamine signaling by b
Externí odkaz:
https://doaj.org/article/55a30220d681412ebe56c8f135171b31
Autor:
Shigemi Yoshihara, Yumi Yamada, Hironobu Fukuda, Takayoshi Tsuchiya, Mika Ono, Norimasa Fukuda, Noriko Kanno, Osamu Arisaka
Publikováno v:
Allergology International, Vol 63, Iss 2, Pp 199-203 (2014)
Background: : Exacerbations of bronchial asthma usually occur in the autumn. To our knowledge, however, the effectiveness of drugs for preventing exacerbations of asthma in the autumn has not been studied previously, except for leukotriene receptor a
Externí odkaz:
https://doaj.org/article/0578f0a9a2a249ca98f90ce48295199d
Publikováno v:
Allergology International, Vol 58, Iss 3, Pp 389-393 (2009)
Background: Immunomodulatory therapy has been recently introduced for the management of asthma. Suplatast tosilate (ST), a new immune-modifying drug, is known to improve the airway function by inhibiting the release of Th-2 cytokines. However, its ef
Externí odkaz:
https://doaj.org/article/cce063b2286b4434be843c06b2eb3ff5
Autor:
Shigeki Gorai, Nobuhisa Terada, Tadashi Kobayashi, Tomohiro Nomura, Woo Jeong Kim, Nobuyuki Onai, Kouji Matsushima, Akiyoshi Konno
Publikováno v:
Allergology International, Vol 54, Iss 3, Pp 373-380 (2005)
Background: Thymus and activation-regulated chemokine (TARC/CCL17) is a highly specific ligand for CCR 4. TARC may contribute to the recruitment, activation, and development of Th2 polarized cells that express CCR4. These characteristics have led inv
Externí odkaz:
https://doaj.org/article/d005b416f4364c22ab26054175fa5e1f
Autor:
Yusuke Izumi, Shintaro Miyamoto, Kazuhide Fukuhara, Hiroshi Iwamoto, Yasushi Horimasu, Noboru Hattori, Sachiko Shioya, Kakuhiro Yamaguchi, Taku Nakashima, Shinjiro Sakamoto, Takeshi Masuda, Kazunori Fujitaka, Hironobu Hamada
Publikováno v:
Free Radical Biology and Medicine. 136:52-59
Purpose Although radiotherapy is important in the treatment of malignant thoracic tumors, it has harmful effects on healthy tissues. We previously showed that suplatast tosilate, an anti-allergic agent, scavenged reactive oxygen species (ROS), includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac524c55594885a0c449cb403b2bf8d
https://doi.org/10.1016/j.freeradbiomed.2019.03.024
https://doi.org/10.1016/j.freeradbiomed.2019.03.024
Successful use of montelukast in eosinophilic gastroenteritis: a case report and a literature review
Publikováno v:
BMC Gastroenterology
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-7 (2021)
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-7 (2021)
Background Eosinophilic gastrointestinal disorders, also known as eosinophilic gastroenteritis, are rare inflammatory conditions characterized by eosinophilic infiltration of different parts of the gastrointestinal tract, along with peripheral eosino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb826866d9c73fa191ce6bbf2956178
https://pubmed.ncbi.nlm.nih.gov/34238222
https://pubmed.ncbi.nlm.nih.gov/34238222
Autor:
Keiichi Takahashi
Publikováno v:
International Journal of Surgery Case Reports
Highlights • Eosinophilic mastitis which organ damage is limited to only the breast is very rare. • A case of mastitis by eosinophil infiltration improved by only anti-allergic drugs. • This is an isolated successful case of eosinophilic mastit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a338ea6d673e45f6490d5c6523429a48
https://doi.org/10.1016/j.ijscr.2018.07.014
https://doi.org/10.1016/j.ijscr.2018.07.014
Autor:
Keiichi Sasaki, Shunji Sugawara, Toshinobu Kuroishi, Yukinori Tanaka, Yasuo Endo, Kanan Bando, Teruko Takano-Yamamoto
Publikováno v:
Journal of Investigative Dermatology. 137:1082-1093
We established a mouse model of contact hypersensitivity (CHS) to hydroquinone (HQ), a widespread chemical in our environment. HQ was painted onto flanks; then, HQ was challenged by painting onto ear pinnas on days 7 and 14. The CHS after the second
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b55cc87189b0a66dcbef6db4d5ce3c8
https://doi.org/10.1016/j.jid.2016.12.018
https://doi.org/10.1016/j.jid.2016.12.018