Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Suping Cai"'
Publikováno v:
Meta-Radiology, Vol 2, Iss 1, Pp 100048- (2024)
Alzheimer's disease (AD) is a common genetically related cognitive disorder. Studies have shown that ferroptosis, N⁶-Methyladenosine (M6A) and immune checkpoint are related to the development of AD. However, the effects of these three gene pathways
Externí odkaz:
https://doaj.org/article/5b5c61b01bd24efcb8a9fae2c14b091d
Autor:
Junkai Tan, Xizhen Wang, Suping Cai, Fen He, Daren Zhang, Dongkan Li, Xianjun Zhu, Liang Zhou, Ning Fan, Xuyang Liu
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 143-155 (2020)
Glaucoma is a lifelong disease with elevated intraocular pressure (IOP) as the main risk factor, and reduction of IOP remains the major treatment for this disease. However, current IOP-lowering therapies are far from being satisfactory. We have demon
Externí odkaz:
https://doaj.org/article/f8f7871d27574c7e9a6d1b242370d2f1
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Mild cognitive impairment (MCI) is a transition between normal cognition (NC) and Alzheimer’s disease (AD). Differences in cortical thickness (ΔCT) have been reported in cases that degenerate from MCI to AD. The aspects of genetic and transcriptio
Externí odkaz:
https://doaj.org/article/dcb91c93265745ea82d704d077f9dbcd
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
ObjectivesThe frontal-striatum-thalamus pathway is important in the glutamic neural circuit. The hypofunction of GRIN1 and GRIA2 subunits from glutamic receptors has been hypothesized as the primary process in the etiology of schizophrenia. Identifie
Externí odkaz:
https://doaj.org/article/703959ff7c1548f395a51e37b5bc6432
Autor:
Xiaohong Li, Fen He, B'Ann T Gabelt, Yun Wang, Suping Cai, Juanhui Cao, Ning Fan, Paul L Kaufman, Xuyang Liu
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151644 (2016)
BACKGROUND AND PURPOSE:The intraocular pressure (IOP)-lowering and side effects in response to different prostaglandin F2α analogues can be variable, but, the underlying basis for this difference remains unknown. This study investigated the differen
Externí odkaz:
https://doaj.org/article/2a95b11778ff45ee97493f8b49ae1bfd
Autor:
Suping Cai, Liyu Huang, Jia Zou, Longlong Jing, Buzhong Zhai, Gongjun Ji, Karen M von Deneen, Junchan Ren, Aifeng Ren, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115573 (2015)
We used resting-state functional magnetic resonance imaging (fMRI) to investigate changes in the thalamus functional connectivity in early and late stages of amnestic mild cognitive impairment. Data of 25 late stages of amnestic mild cognitive impair
Externí odkaz:
https://doaj.org/article/907ea3cc3f6a4b38bc957897a585c02e
Autor:
Ming Yang, Xiaohong Li, Lan Lu, Xuyang Liu, Xizhen Wang, Fen He, Ning Fan, Suping Cai, Tong Zhang
Publikováno v:
Eye. 36:1631-1638
OBJECTIVES To investigate the role of polymorphism rs11200638 of high-temperature requirement factor A-1 (HtrA1) gene in the pathogenesis of age-related macular degeneration (AMD). METHODS Cultured adult retinal pigment epithelial cells (ARPE-19) exp
Publikováno v:
Autism Research. 14:265-275
Systematically describing the structural topological configuration of human brain during development is an essential task. Autism spectrum disorder (ASD) represents a powerful challenge for psychiatry and neuroscience researchers. In this study, we i
Publikováno v:
Schizophrenia Research. 216:213-221
The 5-hydroxytryptamine 2A receptor (5-HT2A) and dopamine D3 receptor (DRD3) have been extensively studied as promising candidate genes for schizophrenia. Magnetic resonance imaging studies have demonstrated that schizophrenia is associated with wide
Publikováno v:
European Journal of Neuroscience. 51:2134-2142
Negative symptoms in schizophrenia have been associated with functional changes in frontostriatal pathways. Dysregulation of the dopamine signal in frontostriatal pathways leads to the symptomology observed in schizophrenia. Although the catechol-O-m