Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Supinder Bedi"'
Autor:
Assaf Gottlieb, Naama Toledano-Furman, Karthik S. Prabhakara, Akshita Kumar, Henry W. Caplan, Supinder Bedi, Charles S. Cox, Scott D. Olson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Traumatic brain injury (TBI) results in a cascade of cellular responses, which produce neuroinflammation, partly due to the activation of microglia. Accurate identification of microglial populations is key to understanding therapeutic approa
Externí odkaz:
https://doaj.org/article/23b474813678411bab4e7276522ecb56
Autor:
Zhanglong Peng, Supinder Bedi, Vivek Mann, Alamelu Sundaresan, Kohei Homma, Gregory Gaskey, Minoru Kowada, Shahid Umar, Anil D. Kulkarni, Holger K. Eltzschig, Marie-Francoise Doursout
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
To mimic Alzheimer’s disease, transgenic mice overexpressing the amyloid precursor protein (APP) were used in this study. We hypothesize that the neuroprotective effects of ETAS®50, a standardized extract of Asparagus officinalis stem produced by
Externí odkaz:
https://doaj.org/article/4fb0b1a81adf419c886cd5eb9b536d91
Autor:
Margaret L. Jackson, Katherine A. Ruppert, Daniel J. Kota, Karthik S. Prabhakara, Robert A. Hetz, Benjamin M. Aertker, Supinder Bedi, Robert W. Mays, Scott D. Olson, Charles S. Cox, Jr.
Publikováno v:
Heliyon, Vol 5, Iss 10, Pp e02532- (2019)
Background: Human multipotent adult progenitor cells (MAPC®) are an emerging therapy for traumatic brain injury (TBI); however, clinically translating a therapy involves overcoming many factors in vivo which are not present in pre-clinical testing.
Externí odkaz:
https://doaj.org/article/e6983ac4ad914b2bb0937e6c8ba04969
Autor:
Henry Caplan, Scott D. Olson, Akshita Kumar, Mitchell George, Karthik S. Prabhakara, Pamela Wenzel, Supinder Bedi, Naama E. Toledano-Furman, Fabio Triolo, Julian Kamhieh-Milz, Guido Moll, Charles S. Cox
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
For several decades, multipotent mesenchymal stromal cells (MSCs) have been extensively studied for their therapeutic potential across a wide range of diseases. In the preclinical setting, MSCs demonstrate consistent ability to promote tissue healing
Externí odkaz:
https://doaj.org/article/7dc7bc6adfe844da8ceba9381f2461fe
Autor:
George P. Liao, Benjamin M. Aertker, Daniel J. Kota, Karthik S. Prabhakara, Philipp Smith, Robert A. Hetz, Hasen Xue, Supinder Bedi, Scott D. Olson, Charles S. Cox
Publikováno v:
ADMET and DMPK, Vol 3, Iss 3, Pp 182-189 (2015)
The blood brain barrier plays an important role in traumatic brain injury, serving at the crossroads of secondary injury and potential therapies. In regards to trauma, this barrier contains an array of cellular and molecular components that protect t
Externí odkaz:
https://doaj.org/article/b8bb097843cf4017ad11c3a8874f2bf8
Autor:
Junling Gao, Raymond J. Grill, Tiffany J. Dunn, Supinder Bedi, Javier Allende Labastida, Robert A. Hetz, Hasen Xue, Jason R. Thonhoff, Douglas S. DeWitt, Donald S. Prough, Charles S. Cox M.D., Ping Wu M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Neural stem cells (NSCs) promote recovery from brain trauma, but neuronal replacement is unlikely the sole underlying mechanism. We hypothesize that grafted NSCs enhance neural repair at least partially through modulating the host immune response aft
Externí odkaz:
https://doaj.org/article/7b3bf25a8f5b48fab8f6150528fa5b1b
Autor:
Supinder Bedi, Minoru Kowada, Vivek Mann, Alamelu Sundaresan, Kohei Homma, Gregory Gaskey, Zhanglong Peng, Holger K. Eltzschig, Shahid Umar, Anil D. Kulkarni, Marie-Francoise Doursout
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
To mimic Alzheimer’s disease, transgenic mice overexpressing the amyloid precursor protein (APP) were used in this study. We hypothesize that the neuroprotective effects of ETAS®50, a standardized extract of Asparagus officinalis stem produced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436c997a118027f0e2914eeccf011478
Autor:
Benjamin m Aertker, Akshita Kumar, Henry W Caplan, Fanni B Cardenas, Charles S Cox, Supinder Bedi
Background: Traumatic brain injury (TBI) disrupts the complex arrangement of neuronal and glial cells. As a result of TBI there is activation of microglia. Activated microglia after injury can be measured in vivo by using positron emission topography
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86c51529d91504c60157ef318630149a
https://doi.org/10.21203/rs.3.rs-66205/v1
https://doi.org/10.21203/rs.3.rs-66205/v1
Autor:
Zhanglong, Peng, Supinder, Bedi, Vivek, Mann, Alamelu, Sundaresan, Kohei, Homma, Gregory, Gaskey, Minoru, Kowada, Shahid, Umar, Anil D, Kulkarni, Holger K, Eltzschig, Marie-Francoise, Doursout
Publikováno v:
Journal of Immunology Research
To mimic Alzheimer's disease, transgenic mice overexpressing the amyloid precursor protein (APP) were used in this study. We hypothesize that the neuroprotective effects of ETAS®50, a standardized extract of Asparagus officinalis stem produced by Am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7849ff9fc6d64b3f515781e3a08f5006
https://pubmed.ncbi.nlm.nih.gov/34046506
https://pubmed.ncbi.nlm.nih.gov/34046506
Publikováno v:
Transfusion. 59(S1)
Clinical trials for traumatic brain injury (TBI) have not successfully produced a new therapeutic for neuroprotection or neurorestoration, despite multiple attempts. Stem cell-based therapies and/or cellular therapies have been developed over the pas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b88154e03da5d78c8cbdef1625587dba
https://pubmed.ncbi.nlm.nih.gov/30737818
https://pubmed.ncbi.nlm.nih.gov/30737818