Post-mortem Findings of Inflammatory Cells and the Association of 4-Hydroxynonenal with Systemic Vascular and Oxidative Stress in Lethal COVID-19

Autor: Neven Zarkovic, Antonia Jakovcevic, Ana Mataic, Morana Jaganjac, Tea Vukovic, Georg Waeg, Kamelija Zarkovic

Publikováno v: Cells, Vol 11, Iss 444, p 444 (2022)
Cells
Cells; Volume 11; Issue 3; Pages: 444

A recent comparison of clinical and inflammatory parameters, together with biomarkers of oxidative stress, in patients who died from aggressive COVID-19 and survivors suggested that the lipid peroxidation product 4-hydroxynonenal (4-HNE) might be det

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21fe8e23b27d41c9e3b7e62e39a9caa8
https://doi.org/10.3390/cells11030444

Calorie Restriction in Adulthood Reduces Hepatic Disorders Induced by Transient Postnatal Overfeeding in Mice

Autor: Na Li, Dolores Mosig, Christian Juvet, Umberto Simeoni, Thibaud. Rolle, Benazir Siddeek, Anithan Krishnasamy, Eve Rigal, Catherine Yzydorczyk, Catherine Vergely, Eulalia Orozco, Hassib Chehade, Jean Baptiste Armengaud

Publikováno v: Nutrients
Nutrients, MDPI, 2019, 11, ⟨10.3390/nu11112796⟩
Volume 11
Issue 11
Nutrients, vol. 11, no. 11
Nutrients, Vol 11, Iss 11, p 2796 (2019)

International audience; Impaired early nutrition influences the risk of developing metabolic disorders in later life. We observed that transient postnatal overfeeding (OF) in mice induces long-term hepatic alterations, characterized by microsteatosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3857d329f348dbe81217e939a02709
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-03416923

Exercise Training Has Contrasting Effects in Myocardial Infarction and Pressure Overload Due to Divergent Endothelial Nitric Oxide Synthase Regulation

Autor: Dirk J. Duncker, Elza D. van Deel, Yanti Octavia, Monique C. de Waard, Martine de Boer

Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 7, p 1968 (2018)
International Journal of Molecular Sciences
International journal of molecular sciences, 19(7):1968. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 19
Issue 7
International Journal of Molecular Sciences, 19(7):1968. Multidisciplinary Digital Publishing Institute (MDPI)

The beneficial effects of exercise training (EX) on cardiac pathology are well recognized. Previously, we found that the effects of EX on cardiac dysfunction in mice critically depend on the underlying etiology. EX exerted beneficial effects after my

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995bd0fff58c81a51d74aa50a010e5b2
https://doi.org/10.3390/ijms19071968

Prevention of age-induced N(ε)-(carboxymethyl)lysine accumulation in the microvasculature

Autor: Zurab Kakabadze, Koba Kupreishvili, Elisa Meinster, Hans W. N. Niessen, Paul A.J. Krijnen, Ekatarina Berishvili, Hjalmar J. De Graaff, Wessel W. Fuijkschot, Casper G. Schalkwijk, Alexander B.A. Vonk, Yvo M. Smulders, Maaike Houtman, Amber van Broekhoven

Publikováno v: European Journal of Clinical Investigation, 46(4), 334-341
Fuijkschot, W W, de Graaff, H J, Berishvili, E, Kakabadze, Z, Kupreishvili, K, Meinster, E, Houtman, M, van Broekhoven, A, Schalkwijk, C G, Vonk, A B A, Krijnen, P A J, Smulders, Y M & Niessen, H W N 2016, ' Prevention of age-induced N(ε)-(carboxymethyl)lysine accumulation in the microvasculature ', European Journal of Clinical Investigation, vol. 46, no. 4, pp. 334-341 . https://doi.org/10.1111/eci.12599
European Journal of Clinical Investigation, Vol. 46, No 4 (2016) pp. 334-341
European Journal of Clinical Investigation, 46(4), 334-341. Wiley

OBJECTIVE: N(ε)-(carboxymethyl)lysine (CML) is one of the major advanced glycation end products in both diabetics and nondiabetics. CML depositions in the microvasculature have recently been linked to the aetiology of acute myocardial infarction and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5448192d4cb910f4db501fb447267b86
https://research.vumc.nl/en/publications/2c418ddc-8edf-42c7-b7d1-4a1796a065d6

Reduced expression of the NADPH oxidase NOX4 is a hallmark of adipocyte differentiation

Autor: C. Ronald Kahn, Masa Katic, Sanae Ben Mkaddem, Klaus Steger, Yu-Hua Tseng, Wei Wang, Stephanie Carnesecchi, Ildiko Szanto, Christoph A. Meier, Sarah Mouche, Eric Ogier-Denis, Patrick Muzzin, Michelangelo Foti

Publikováno v: Biochimica et Biophysica Acta, Vol. 1773, No 7 (2007) pp. 1015-27

Adipocyte differentiation is a complex process regulated among other factors by insulin and the production of reactive oxygen species (ROS). NOX4 is a ROS generating NADPH oxidase enzyme mediating insulin′s action in 3T3L1 adipocytes. In the presen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ca868b282e7476fbfc2becba61ef39
https://doi.org/10.1016/j.bbamcr.2007.03.003