Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sunyoung Chae"'
Autor:
Ho-Soo Lee, Sunwoo Min, Ye-Eun Jung, Sunyoung Chae, June Heo, Jae-Ho Lee, TaeSoo Kim, Ho-Chul Kang, Makoto Nakanish, Sun-Shin Cha, Hyeseong Cho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
During cell division, chromosome alignment is engendered by connection of microtubules to kinetochores, coordinated by Aurora B and PLK1. Here, the authors show that the RSF1-PLK1 axis creates an activating phosphorylation on T236 in the GT motif of
Externí odkaz:
https://doaj.org/article/85496129839748b6b42b54a47eb01f4f
Autor:
Geun-Hyoung Ha, Jae-Hoon Ji, Sunyoung Chae, Jihyun Park, Suhyeon Kim, Jin-Kwan Lee, Yonghyeon Kim, Sunwoo Min, Jeong-Min Park, Tae-Hong Kang, Ho Lee, Hyeseong Cho, Chang-Woo Lee
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Occurrence of DNA double-strand break (DSB) repair is important for genome integrity. Here, the authors reveal that Pellino1 is a DSB-responsive ubiquitin ligase required for promoting the accumulation of ATM and MRN complex at DSB sites via NBS1 ubi
Externí odkaz:
https://doaj.org/article/ee92c7e083594457b9d565bc9efb1942
Autor:
Ho-Soo Lee, Zhonghui Lin, Sunyoung Chae, Young-Suk Yoo, Byung-Gyu Kim, Youngsoo Lee, Jared L. Johnson, You-Sun Kim, Lewis C. Cantley, Chang-Woo Lee, Hongtao Yu, Hyeseong Cho
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The chromatin remodeler RSF1 is enriched at mitotic centromeres but its function there is poorly understood. Here, the authors show that RSF1 regulates H2A phosphorylation and acetylation at mitotic centromeres and contributes to chromosome stability
Externí odkaz:
https://doaj.org/article/0bf89570019f4e5fb76ec6c3b0d31610
Autor:
June Heo, Sunyoung Chae, Jae-Ho Lee, Ho-Soo Lee, Sun Shin Cha, Kang Hy, TaeSoo Kim, Ye-Eun Jung, Makoto Nakanish, Sunwoo Min, Hyeseong Cho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
The chromatin remodeler RSF1 enriched at mitotic centromeres is essential for proper chromosome alignment and segregation and underlying mechanisms remain to be disclosed. We here show that PLK1 recruitment by RSF1 at centromeres creates an activatin
Autor:
Yiseul Hwang, Chan Gil Kim, Junghyun Yoon, Hongtae Kim, Ho Chul Kang, Valina L. Dawson, Soyeon Kim, Sangwook Park, Jee Min Chung, Ted M. Dawson, Jae-Hoon Ji, Hansol Yun, Sunyoung Chae, Hyeseong Cho, Seo Yun Lee, Jae Jin Kim
Publikováno v:
Nucleic Acids Research
Mutual crosstalk among poly(ADP-ribose) (PAR), activated PAR polymerase 1 (PARP1) metabolites, and DNA repair machinery has emerged as a key regulatory mechanism of the DNA damage response (DDR). However, there is no conclusive evidence of how PAR pr
Autor:
Sunyoung Chae, Sunwoo Min, Y. C. Kim, Jae-Hoon Ji, Chang-Woo Lee, Hyeseong Cho, Geun-Hyoung Ha, Yeon Ji Park
Publikováno v:
Nucleic Acids Research
Histone H2AX undergoes a phosphorylation switch from pTyr142 (H2AX-pY142) to pSer139 (γH2AX) in the DNA damage response (DDR); however, the functional role of H2AX-pY142 remains elusive. Here, we report a new layer of regulation involving transcript
Autor:
Chanmi Cho, Jin Sil Lee, Hyeryeon Oh, Li‐Jung Kang, Yiseul Hwang, Sunyoung Chae, In‐Jeong Lee, Seok Jung Kim, Hyunmin Woo, Seong‐il Eyun, Ho Chul Kang, Won Il Choi, Siyoung Yang
Publikováno v:
Small. 18:2202146
Autor:
Lewis C. Cantley, Youngsoo Lee, Chang-Woo Lee, Sunyoung Chae, Young Suk Yoo, You-Sun Kim, Ho Soo Lee, Jared L. Johnson, Byung-Gyu Kim, Hyeseong Cho, Hongtao Yu, Zhonghui Lin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Chromatin remodelers regulate the nucleosome barrier during transcription, DNA replication, and DNA repair. The chromatin remodeler RSF1 is enriched at mitotic centromeres, but the functional consequences of this enrichment are not completely underst
Autor:
Ho Lee, Chang-Woo Lee, Jeong-Min Park, Sunyoung Chae, Hyeseong Cho, Tae-Hong Kang, Sunwoo Min, Jihyun Park, Jae-Hoon Ji, Suhyeon Kim, Jin-Kwan Lee, Geun-Hyoung Ha, Y. C. Kim
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
DNA double-strand break (DSB) signaling and repair are critical for genome integrity. They rely on highly coordinated processes including posttranslational modifications of proteins. Here we show that Pellino1 (Peli1) is a DSB-responsive ubiquitin li
Publikováno v:
Cell Cycle. 13:666-677
As a member of imitation switch (ISWI) family in ATP-dependent chromatin remodeling factors, RSF complex consists of SNF2h ATPase and Rsf-1. Although it has been reported that SNF2h ATPase is recruited to DNA damage sites (DSBs) in a poly(ADP-ribosyl