Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sunny Sun-Kin Chan"'
Autor:
Sunny Sun-Kin Chan, Hannah R. Hagen, Scott A. Swanson, Ron Stewart, Karly A. Boll, Joy Aho, James A. Thomson, Michael Kyba
Publikováno v:
Stem Cell Reports, Vol 6, Iss 1, Pp 26-34 (2016)
The branchiomeric skeletal muscles co-evolved with new chambers of the heart to enable predatory feeding in chordates. These co-evolved tissues develop from a common population in anterior splanchnic mesoderm, referred to as cardiopharyngeal mesoderm
Externí odkaz:
https://doaj.org/article/97e2ae48153c4964bdc8513f92684a80
Autor:
Sunny Sun-Kin Chan, Hui-Jing Li, Ying-Chang Hsueh, Desy S Lee, Jyh-Hong Chen, Shiaw-Min Hwang, Chen-Yun Chen, Emily Shih, Patrick C H Hsieh
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14414 (2010)
BACKGROUND: The fibroblast growth factor (FGF) family is essential to normal heart development. Yet, its contribution to cardiomyocyte differentiation from stem cells has not been systemically studied. In this study, we examined the mechanisms and ch
Externí odkaz:
https://doaj.org/article/703a457db3394fbfbe46407deeb5b360
Autor:
Sunny Sun Kin Chan, Lindsay N. Peifer, Michael Kyba, Karim Azzag, Sabrina N. Chu, Rita C.R. Perlingeiro, Ning Xie, Cassandra B. Schultz
Publikováno v:
Stem Cell Reports
Summary One major challenge in realizing cell-based therapy for treating muscle-wasting disorders is the difficulty in obtaining therapeutically meaningful amounts of engraftable cells. We have previously described a method to generate skeletal myoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e2c02901edf996ee566231bf417274
https://doi.org/10.1016/j.stemcr.2021.10.014
https://doi.org/10.1016/j.stemcr.2021.10.014
Publikováno v:
Biochemical and Biophysical Research Communications. 520:284-290
The Mesp1 lineage contributes to cardiac, hematopoietic and skeletal myogenic development. Interestingly, muscle stem cells residing in craniofacial skeletal muscles primarily arise from Mesp1+ progenitors, but those in trunk and limb skeletal muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38b8060249b654824a41e6fa6eb2d3b
https://doi.org/10.1016/j.bbrc.2019.09.140
https://doi.org/10.1016/j.bbrc.2019.09.140
Autor:
Andrew D. Hoffmann, Jessica Jacobs-Li, Alexander Guzzetta, Ariel B. Rydeen, Ivan P. Moskowitz, Sonja Lazarevic, Sunny Sun Kin Chan, Michael Kyba, Daniel J. Garry, Chul Kim, Perez-Cervantes Carlos, Megan Rowton, Emery Lu, Jeffrey D. Steimle, Mervenaz Koska, Shuhan Yu, Kohta Ikegami, Nikita Deng, Xinan Yang, Erika Hanson
Publikováno v:
Circulation Research. 127
The first heart field (FHF) and the second heart field (SHF) comprise the major progenitor pools for the developing vertebrate heart. We investigated the delayed differentiation of the SHF relative to the FHF, a major distinguishing feature of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d10a942ef329367dc8570a9e2ad657a
https://doi.org/10.1161/res.127.suppl_1.541
https://doi.org/10.1161/res.127.suppl_1.541
Publikováno v:
Development, growthdifferentiationREFERENCES. 62(7-8)
Efficient derivation of cardiomyocytes from mouse pluripotent stem cells has proven challenging, and existing approaches rely on expensive supplementation or extensive manipulation. Mesp1 is a transcription factor that regulates cardiovascular specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae716cc2fa700cbb004a687adeccfd6f
https://pubmed.ncbi.nlm.nih.gov/33048365
https://pubmed.ncbi.nlm.nih.gov/33048365
Autor:
Sarah M. Greising, Gordon L. Warren, Dawn A. Lowe, Tara L. Mader, Sunny Sun Kin Chan, Gengyun Le, Michael Kyba, Susan A. Novotny
Publikováno v:
The Journal of Physiology. 596:4665-4680
Key points The female hormone oestrogen may protect muscle from injury by reducing inflammation but this is debatable. In this study, the inflammatory response of injured muscle from oestrogen-replete mice was comprehensively compared to that from oe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::721380f4be67bdfd3472710d3323751b
https://doi.org/10.1113/jp276432
https://doi.org/10.1113/jp276432
Autor:
Lynn M. Hartweck, Olivia O. Recht, Collin J Gustafson, Dawn A. Lowe, Laura L. Athman, Sunny Sun Kin Chan, Michael Kyba, Darko Bosnakovski
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Facioscapulohumeral muscular dystrophy is a slowly progressive but devastating myopathy caused by loss of repression of the transcription factor DUX4; however, DUX4 expression is very low, and protein has not been detected directly in patient biopsie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0fc654700e289a29bc217dfa79634a3
http://link.springer.com/article/10.1038/s41467-017-00730-1
http://link.springer.com/article/10.1038/s41467-017-00730-1
Autor:
Alessandro Magli, Michael Kyba, Jianbo Wu, Vanessa K.P. Oliveira, Radbod Darabi, Rita C.R. Perlingeiro, Jaemin Kim, Sunny Sun Kin Chan
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 9, Iss 1, Pp 12-22 (2017)
Stem Cell Reports, Vol 9, Iss 1, Pp 12-22 (2017)
Summary Recent reports have documented the differentiation of human pluripotent stem cells toward the skeletal myogenic lineage using transgene- and cell purification-free approaches. Although these protocols generate myocytes, they have not demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23bcaf78be952cdff2c62f29d08668e
https://doi.org/10.1016/j.stemcr.2017.04.022
https://doi.org/10.1016/j.stemcr.2017.04.022
Autor:
Michael Kyba, Bhairab N. Singh, Pruthvi Shah, Mary G. Garry, Sunny Sun Kin Chan, Wuming Gong, Joshua W.M. Theisen, Satyabrata Das, Demetris Yannopoulos, Wei Pan, Daniel J. Garry
Single cell RNA-seq (scRNA-seq) over specified time periods has been widely used to dissect the cell populations during mammalian embryogenesis. Integrating such scRNA-seq data from different developmental stages and from different laboratories is cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3955d85a9168a89155ab4a5db25d49a0
