ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release

Autor: Piet Borst, Koen van de Wetering, Jon A. Otero, Sunny Sapthu, Marcel de Haas, Asli Kucukosmanoglu, Theo G. M. F. Gorgels, Robert S. Jansen, Arthur A.B. Bergen, Ilse E. M. Hegman

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 110(50), 20206-20211. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 110, 20206-20211. National Academy of Sciences
Jansen, R S, Küçükosmanoǧlu, A, De Haas, M, Sapthu, S, Otero, J A, Hegman, I E M, Bergen, A A B, Gorgels, T G M F, Borst, P & Van De Wetering, K 2013, ' ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release ', Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 50, pp. 20206-20211 . https://doi.org/10.1073/pnas.1319582110

Pseudoxanthoma elasticum (PXE) is an autosomal recessive disease characterized by progressive ectopic mineralization of the skin, eyes, and arteries, for which no effective treatment exists. PXE is caused by inactivating mutations in the gene encodin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b31be1682a2a3991d0f478d83613a89
https://doi.org/10.1073/pnas.1319582110