Zobrazeno 1 - 10
of 309
pro vyhledávání: '"Sunny H, Wong"'
Autor:
Wenye Xu, Yuchen Zhang, Dongjiao Chen, Dan Huang, Yang Zhao, Wei Hu, Ling Lin, Yingzhi Liu, Shilan Wang, Judeng Zeng, Chuan Xie, Hung Chan, Qing Li, Huarong Chen, Xiaodong Liu, Sunny H. Wong, Jun Yu, Francis K. L. Chan, Matthew T. V. Chan, Siew C. Ng, William K. K. Wu, Lin Zhang
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Fusobacterium nucleatum (F. nucleatum) is one of the key tumorigenic bacteria in colorectal cancer (CRC), yet how F. nucleatum is involved in colorectal cancer carcinogenesis remains unknown. Results In the present study, we carri
Externí odkaz:
https://doaj.org/article/b61bd6e59fff42d584fb0a93eec26fe1
Autor:
Wilson Sim, Jason Timothy Pan, Cheryl Wan Xuan Chua, Khi Yung Fong, Sunny H Wong, Bernett Lee, Hazel H Oon
Publikováno v:
Annals, Academy of Medicine, Singapore, Vol 53, Iss 7, Pp 420-434 (2024)
Introduction: Alcohol flushing syndrome (AFS) is experienced by up to 46% of East Asians. This study aimed to review the risk of cancers in AFS patients, elucidate an exposure-response relationship, and understand risk associated with alcohol intake
Externí odkaz:
https://doaj.org/article/389f1401f4a84e4481adb80eb07db08d
Autor:
Md Nannur Rahman, Nilakshi Barua, Martha C.F. Tin, Priyanga Dharmaratne, Sunny H. Wong, Margaret Ip
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTRepeated exposure to antibiotics and changes in the diet and environment shift the gut microbial diversity and composition, making the host susceptible to pathogenic infection. The emergence and ongoing spread of AMR pathogens is a challengin
Externí odkaz:
https://doaj.org/article/62e6f77d9d6e4f759989d44186931244
Autor:
Judeng Zeng, Chuan Xie, Ziheng Huang, Chi H. Cho, Hung Chan, Qing Li, Hassan Ashktorab, Duane T. Smoot, Sunny H. Wong, Jun Yu, Wei Gong, Cong Liang, Hongzhi Xu, Huarong Chen, Xiaodong Liu, Justin C. Y. Wu, Margaret Ip, Tony Gin, Lin Zhang, Matthew T. V. Chan, Wei Hu, William K. K. Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The role of N6-methyladenosine (m6A) modification of host mRNA during bacterial infection is unclear. Here, we show that Helicobacter pylori infection upregulates host m6A methylases and increases m6A levels in gastric epithelial cells. Redu
Externí odkaz:
https://doaj.org/article/faf3d02f8eca48d192ffb1a37c4210da
Publikováno v:
Intestinal Research, Vol 22, Iss 1, Pp 15-43 (2024)
Inflammatory bowel disease (IBD) is a multifactorial disease, which is thought to be an interplay between genetic, environment, microbiota, and immune-mediated factors. Dysbiosis in the gut microbial composition, caused by antibiotics and diet, is cl
Externí odkaz:
https://doaj.org/article/8809c4cfbe394648b05e67bde1cfc78f
Publikováno v:
Clinical and Molecular Hepatology, Vol 30, Iss 1, Pp 118-120 (2024)
Externí odkaz:
https://doaj.org/article/31e69abaaec24dd08cfde086671896cd
Autor:
Xing Kang, Siu-Kin Ng, Changan Liu, Yufeng Lin, Yunfei Zhou, Thomas N.Y. Kwong, Yunbi Ni, Thomas Y.T. Lam, William K.K. Wu, Hong Wei, Joseph J.Y. Sung, Jun Yu, Sunny H. Wong
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104670- (2023)
Summary: Background: Obesity is a risk factor for colorectal cancer (CRC). The role of gut microbiota in mediating the cancer-promoting effect of obesity is unknown. Methods: Azoxymethane (AOM)-treated, ApcMin/+ and germ-free mice were gavaged with f
Externí odkaz:
https://doaj.org/article/6eff480801eb40048ceea1cc3ee5cdd7
Autor:
Cosmos L.T. Guo, Thomas N.Y. Kwong, Joyce W.Y. Mak, Lin Zhang, Grace C.Y. Lui, Grace L.H. Wong, Margaret Ip, Jun Yu, Joseph J.Y. Sung, William K.K. Wu, Sunny H. Wong
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 12, Pp 3036-3044 (2021)
We conducted a territorywide survey to investigate the epidemiology, risk factors, and clinical outcomes of Clostridioides difficile infection (CDI) among hospitalized patients in Hong Kong. A total of 17,105 cases of CDI were identified, of which 15
Externí odkaz:
https://doaj.org/article/7b3b80364d4f489c88ddb93f61ac8ab3
Autor:
Carmen C. Y. Poon, Yuqi Jiang, Ruikai Zhang, Winnie W. Y. Lo, Maggie S. H. Cheung, Ruoxi Yu, Yali Zheng, John C. T. Wong, Qing Liu, Sunny H. Wong, Tony W. C. Mak, James Y. W. Lau
Publikováno v:
npj Digital Medicine, Vol 3, Iss 1, Pp 1-8 (2020)
Abstract We have designed a deep-learning model, an “Artificial Intelligent Endoscopist (a.k.a. AI-doscopist)”, to localise colonic neoplasia during colonoscopy. This study aims to evaluate the agreement between endoscopists and AI-doscopist for
Externí odkaz:
https://doaj.org/article/770504c377534cd0bd60f862a5912cdc
Autor:
Jeffery Ho, Hung Chan, Yonghao Liang, Xiaodong Liu, Lin Zhang, Qing Li, Yuchen Zhang, Judeng Zeng, Felix N. Ugwu, Idy H. T. Ho, Wei Hu, Johnny C. W. Yau, Sunny H. Wong, Wai Tat Wong, Lowell Ling, Chi H. Cho, Richard L. Gallo, Tony Gin, Gary Tse, Jun Yu, Matthew T. V. Chan, Czarina C. H. Leung, William K. K. Wu
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-16 (2020)
Abstract Objectives The intestinal epithelium compartmentalizes the sterile bloodstream and the commensal bacteria in the gut. Accumulating evidence suggests that this barrier is impaired in sepsis, aggravating systemic inflammation. Previous studies
Externí odkaz:
https://doaj.org/article/7d62813e15f84a7bb7e67e903aed1b8b