Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Sunjoo, Ahn"'
Autor:
Mihyun Bae, Junyeop Daniel Roh, Youjoung Kim, Seong Soon Kim, Hye Min Han, Esther Yang, Hyojin Kang, Suho Lee, Jin Yong Kim, Ryeonghwa Kang, Hwajin Jung, Taesun Yoo, Hyosang Kim, Doyoun Kim, Heejeong Oh, Sungwook Han, Dayeon Kim, Jinju Han, Yong Chul Bae, Hyun Kim, Sunjoo Ahn, Andrew M Chan, Daeyoup Lee, Jin Woo Kim, Eunjoon Kim
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2653-2653 (2024)
Externí odkaz:
https://doaj.org/article/2d03b1ed267d47f38fffedfba864727a
Publikováno v:
BMC Neuroscience, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Several phosphodiesterase 4 (PDE4) inhibitors have emerged as potential therapeutics for central nervous system (CNS) diseases. This study investigated the pharmacological effects of two selective PDE4 inhibitors, roflumilast and
Externí odkaz:
https://doaj.org/article/4b7d62c2fa5d4890b4ef50d769a9434b
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3532-3539 (2023)
Stability of compounds in the human plasma is crucial for maintaining sufficient systemic drug exposure and considered an essential factor in the early stages of drug discovery and development. The rapid degradation of compounds in the plasma can res
Externí odkaz:
https://doaj.org/article/bd4d78c3b6b540fa9bbc02740bd52450
Autor:
Hyosang Kim, Doyoun Kim, Yisul Cho, Kyungdeok Kim, Junyeop Daniel Roh, Yangsik Kim, Esther Yang, Seong Soon Kim, Sunjoo Ahn, Hyun Kim, Hyojin Kang, Yongchul Bae, Eunjoon Kim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
ARID1B is a chromatin remodeler associated with autism spectrum disorders. Here the authors demonstrate that early postnatal serotonin modulation prevents adult stage deficits in Arid1b-deficient mice through synaptic transcriptional reprogramming.
Externí odkaz:
https://doaj.org/article/4c33d5e79d574c718ca4713148f36998
Autor:
Mihyun Bae, Junyeop Daniel Roh, Youjoung Kim, Seong Soon Kim, Hye Min Han, Esther Yang, Hyojin Kang, Suho Lee, Jin Yong Kim, Ryeonghwa Kang, Hwajin Jung, Taesun Yoo, Hyosang Kim, Doyoun Kim, Heejeong Oh, Sungwook Han, Dayeon Kim, Jinju Han, Yong Chul Bae, Hyun Kim, Sunjoo Ahn, Andrew M Chan, Daeyoup Lee, Jin Woo Kim, Eunjoon Kim
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 2, Pp 1-27 (2021)
Abstract Glycine transporters (GlyT1 and GlyT2) that regulate levels of brain glycine, an inhibitory neurotransmitter with co‐agonist activity for NMDA receptors (NMDARs), have been considered to be important targets for the treatment of brain diso
Externí odkaz:
https://doaj.org/article/e7bd2f5e0b814f6d81ea04c17922113e
Autor:
Ha-Young Choi, Bo-Min Kim, Young-Rok Kim, Taehui Yang, Sunjoo Ahn, Dongeun Yong, Jin-Hwan Kwak, Won-Gon Kim
Publikováno v:
Antibiotics, Vol 11, Iss 7, p 902 (2022)
Coralmycins, such as coralmycin A and DH-coralmycin A, have novel molecular skeletons and have been reported to exhibit potent antibacterial activity against standard Gram-positive bacterial strains. Here, the in vitro antibacterial activity against
Externí odkaz:
https://doaj.org/article/b94d319610f647a1a357a99c69d6b892
Encapsulation and Enhanced Delivery of Topoisomerase I Inhibitors in Functionalized Carbon Nanotubes
Autor:
Sieun Chae, Dahee Kim, Kyung-jin Lee, Dasol Lee, Young-O Kim, Yong Chae Jung, Sang Dal Rhee, Kwang Rok Kim, Jeong-O Lee, Sunjoo Ahn, Byumseok Koh
Publikováno v:
ACS Omega, Vol 3, Iss 6, Pp 5938-5945 (2018)
Externí odkaz:
https://doaj.org/article/d00cad212f984af4a59c8b89270e9675
Autor:
Ji Hun, Lee, Sang Hee, Ji, Jong Seung, Lim, Sunjoo, Ahn, Hwi-Yeol, Yun, Seong Hwan, Kim, Jin Sook, Song
Publikováno v:
Neurochemical Research. 47:3829-3837
Selonsertib is a first-in-class apoptosis signal-regulating kinase 1 (ASK1) inhibitor in clinical trials for treating NASH and diabetic kidney disease due to its anti-inflammatory and anti-fibrotic activities. In the present study, we investigated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c390ce2f61929b94664e695fb0a70a
https://doi.org/10.1007/s11064-022-03777-9
https://doi.org/10.1007/s11064-022-03777-9
Autor:
Yoo-Kyung Song, Yun-Hwan Seol, Min Ju Kim, Jong-Woo Jeong, Hae-In Choi, Seung-Won Lee, Yoon-Jee Chae, Sunjoo Ahn, Young-Dae Gong, Kyeong-Ryoon Lee, Tae-Sung Koo
Publikováno v:
Pharmaceutics, Vol 13, Iss 3, p 373 (2021)
Supinoxin is a novel anticancer drug candidate targeting the Y593 phospho-p68 RNA helicase, by exhibiting antiproliferative activity and/or suppression of tumor growth. This study aimed to characterize the in vitro and in vivo pharmacokinetics of sup
Externí odkaz:
https://doaj.org/article/dcd06b6dbdef4d99bf9cab27fa2aa6dd
Autor:
Byungho Lim, Dabin Yoo, Younghwa Chun, Areum Go, Ji Yeon Kim, Ha Young Lee, Rebecca J. Boohaker, Kyung-Jin Cho, Sunjoo Ahn, Jin Soo Lee, DooYoung Jung, Gildon Choi
Publikováno v:
Cancers; Volume 15; Issue 6; Pages: 1737
Epigenetic dysregulation characterized by aberrant DNA hypermethylation is a hallmark of cancer, and it can be targeted by hypomethylating agents (HMAs). Recently, we described the superior therapeutic efficacy of a novel HMA, namely, NTX-301, when u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299d8f2ece4f475653328d9383d58895