Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Sunitha Nagrath"'
Autor:
Zeqi Niu, Molly Kozminsky, Kathleen C. Day, Luke J. Broses, Marian L. Henderson, Christopher Patsalis, Rebecca Tagett, Zhaoping Qin, Sarah Blumberg, Zachery R. Reichert, Sofia D. Merajver, Aaron M. Udager, Phillip L. Palmbos, Sunitha Nagrath, Mark L. Day
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 57, Iss , Pp 101036- (2024)
Assessing the molecular profiles of bladder cancer (BC) from patients with locally advanced or metastatic disease provides valuable insights, such as identification of invasive markers, to guide personalized treatment. Currently, most molecular profi
Externí odkaz:
https://doaj.org/article/2bf02dafe4674b49bd058a098275693d
Autor:
Emma Purcell, Zeqi Niu, Sarah Owen, Madeline Grzesik, Abigail Radomski, Anna Kaehr, Nna-Emeka Onukwugha, Heather Fairbairn Winkler, Nithya Ramnath, Theodore Lawrence, Shruti Jolly, Sunitha Nagrath
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113687- (2024)
Summary: Circulating tumor cells (CTCs) are early signs of metastasis and can be used to monitor disease progression well before radiological detection by imaging. Using an ultrasensitive graphene oxide microfluidic chip nanotechnology built with gra
Externí odkaz:
https://doaj.org/article/22edef97cc344077b92f9687d1846b85
Autor:
Bhumsoo Kim, Yoon‐Tae Kang, Faye E. Mendelson, John M. Hayes, Masha G. Savelieff, Sunitha Nagrath, Eva L. Feldman
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 11, Pp n/a-n/a (2023)
Abstract The metabolic syndrome (MetS) and Alzheimer's disease share several pathological features, including insulin resistance, abnormal protein processing, mitochondrial dysfunction and elevated inflammation and oxidative stress. The MetS constitu
Externí odkaz:
https://doaj.org/article/fdf9cf5f39e64e109131131091c0e1a5
Myeloid cell reprogramming alleviates immunosuppression and promotes clearance of metastatic lesions
Autor:
Ravi M. Raghani, Jeffrey A. Ma, Yining Zhang, Sophia M. Orbach, Jing Wang, Mina Zeinali, Sunitha Nagrath, Sandeep Kakade, Qichen Xu, Joseph R. Podojil, Tushar Murthy, Adam Elhofy, Jacqueline S. Jeruss, Lonnie D. Shea
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Suppressive myeloid cells, including monocyte and neutrophil populations, play a vital role in the metastatic cascade and can inhibit the anti-tumor function of cytotoxic T-cells. Cargo-free polymeric nanoparticles (NPs) have been shown to modulate i
Externí odkaz:
https://doaj.org/article/bbd23894292c4b84ad0eca87089a47a9
Autor:
Yoon-Tae Kang, Anusha Mutukuri, Thomas Hadlock, Heather Fairbairn, Taylor R. Carle, Shamileh Fouladdel, Vasudha Murlidhar, Aaron Kramer, Monica De Silva Reguera, Ebrahim Azizi, Alison Durham, Scott A. Mclean, Sunitha Nagrath
Publikováno v:
Advanced NanoBiomed Research, Vol 2, Iss 8, Pp n/a-n/a (2022)
Melanoma is one of the most aggressive skin cancers due to its potential to metastasize widely in the body. The risk of metastasis is increased with later detection and increased thickness of the primary lesion, thus early identification/surgical rem
Externí odkaz:
https://doaj.org/article/6ead52aedc5d4865a54a7d6db9e91e25
Autor:
Emma Purcell, Sarah Owen, Emily Prantzalos, Abigail Radomski, Nayri Carman, Ting-Wen Lo, Mina Zeinali, Chitra Subramanian, Nithya Ramnath, Sunitha Nagrath
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
In non-small cell lung cancer (NSCLC), identifying the presence of sensitizing and resistance epidermal growth factor receptor (EGFR) mutations dictates treatment plans. Extracellular vesicles (EVs) are emerging as abundant, stable potential liquid b
Externí odkaz:
https://doaj.org/article/f88f5036fc264c2a81eb9c63bb5ee78c
Autor:
Ting-wen Lo, Claudia Figueroa-Romero, Junguk Hur, Crystal Pacut, Evan Stoll, Calvin Spring, Rose Lewis, Athul Nair, Stephen A. Goutman, Stacey A. Sakowski, Sunitha Nagrath, Eva L. Feldman
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Amyotrophic lateral sclerosis (ALS) is a terminalneurodegenerative disease. Clinical and molecular observations suggest that ALS pathology originates at a single site and spreads in an organized and prion-like manner, possibly driven by extracellular
Externí odkaz:
https://doaj.org/article/096cc19ce0b6428abc876d39c85f314d
Autor:
Michael D Green, Lili Zhao, Dean E Brenner, Cindy Y Jiang, Zeqi Niu, Shelby Raupp, Brittany Pannecouk, Sunitha Nagrath, Nithya Ramnath
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Immunotherapy for cancer is now a standard pillar in the armamentarium of treatments for many cancers. Immune checkpoint inhibitors, in particular, have resulted in significant therapeutic benefit and prolongation of survival in solid organ cancers,
Externí odkaz:
https://doaj.org/article/a3e7592b2b7b405d94fe4e9945cc66b2
Autor:
Yu-Heng Cheng, Yu-Chih Chen, Eric Lin, Riley Brien, Seungwon Jung, Yu-Ting Chen, Woncheol Lee, Zhijian Hao, Saswat Sahoo, Hyun Min Kang, Jason Cong, Monika Burness, Sunitha Nagrath, Max S. Wicha, Euisik Yoon
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Transcriptome analysis of circulating tumor cells (CTCs) provides insights into monitoring target therapeutics and underlying tumor metastasis. Here the authors present Hydro-Seq, a contamination-free high-throughput hydrodynamic scRNA-seq barcoding
Externí odkaz:
https://doaj.org/article/8f568b6e3e6b49b99506d87fda212237
Autor:
Tae Hyun Kim, Yang Wang, C. Ryan Oliver, Douglas H. Thamm, Laura Cooling, Costanza Paoletti, Kaylee J. Smith, Sunitha Nagrath, Daniel F. Hayes
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Ex vivo methods of circulating tumor cell (CTC) isolation use small blood volumes, limiting sensitivity and introducing analytical inaccuracies. The authors describe a proof-of-concept study of an in vivo aphaeresis system that continuously collects
Externí odkaz:
https://doaj.org/article/5e6e1cbabb7f40a58693713234fb08b1