Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sunita Varsani-Brown"'
Autor:
Graham Duddy, Katherine Courtis, Juliette Horwood, Jessica Olsen, Helen Horsler, Tina Hodgson, Sunita Varsani-Brown, Abdullah Abdullah, Laura Denti, Hollie Lane, Fabio Delaqua, Julia Janzen, Molly Strom, Ian Rosewell, Katharine Crawley, Benjamin Davies
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background The ability of recombinant adeno-associated virus to transduce preimplantation mouse embryos has led to the use of this delivery method for the production of genetically altered knock-in mice via CRISPR-Cas9. The potential exists
Externí odkaz:
https://doaj.org/article/95b5ec7dd7854bb08b37eb55094b38d8
Autor:
Nicola Laura Diny, Barbora Schonfeldova, Michael Shapiro, Matthew L. Winder, Sunita Varsani-Brown, Brigitta Stockinger
Publikováno v:
The Journal of experimental medicine. 219(4)
Eosinophils are potent sources of inflammatory and toxic mediators, yet they reside in large numbers in the healthy intestine without causing tissue damage. We show here that intestinal eosinophils were specifically adapted to their environment and u
Autor:
Sunita Varsani-Brown, Natalia Moncaut, Michael D. Buck, Enzo Z. Poirier, Ana Cardoso, Stefano Sammicheli, Oliver Gordon, Probir Chakravarty, Naren Srinivasan, Johnathan Canton, Kok Haw Jonathan Lim, Oliver Schulz, Neil C. Rogers, Evangelos Giampazolias, Santiago Zelenay, Caetano Reis e Sousa, Ian Rosewell
Publikováno v:
Cell
Summary Cross-presentation of antigens from dead tumor cells by type 1 conventional dendritic cells (cDC1s) is thought to underlie priming of anti-cancer CD8+ T cells. cDC1 express high levels of DNGR-1 (a.k.a. CLEC9A), a receptor that binds to F-act
Autor:
Patrick H. Maxwell, Patrick J. Pollard, Deepa Shukla, Richard Poulsom, Ian Tomlinson, Bradley Spencer-Dene, Emma Nye, Ian Rosewell, Peter Igarashi, Alison Martin, Kimberley Howarth, Stuart McDonald, Mona El-Bahrawy, Maria Joannou, Maesha Deheragoda, Sunita Varsani-Brown, Gordon Stamp
Germline mutations in the fumarate hydratase (FH) tumor suppressor gene predispose to leiomyomatosis, renal cysts, and renal cell cancer (HLRCC). HLRCC tumors overexpress HIF1alpha and hypoxia pathway genes. We conditionally inactivated mouse Fh1 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a35eeeea4021dbe9437ddac10c6a27
https://doi.org/10.1016/j.ccr.2007.02.005
https://doi.org/10.1016/j.ccr.2007.02.005