Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sunita Nehra"'
Publikováno v:
Stem Cell Research, Vol 67, Iss , Pp 103041- (2023)
A pair of Down syndrome (DS) human iPSCs (hiPSCs) and isogenic euploid hiPSCs generated by using an integration-free Sendai viral vector system showed trisomy 21 (47; XY) and typical (46; XY) karyotype respectively. Pluripotency of both hiPSC lines w
Externí odkaz:
https://doaj.org/article/0c6cef5290cd4564b202b4a674f6cc15
Autor:
Vishi Sharma, Sunita Nehra, Long H. Do, Anwesha Ghosh, Aniruddha J. Deshpande, Nishant Singhal
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Impaired neurogenesis in Down syndrome (DS) is characterized by reduced neurons, increased glial cells, and delayed cortical lamination. However, the underlying cause for impaired neurogenesis in DS is not clear. Using both human and mouse iPSCs, we
Externí odkaz:
https://doaj.org/article/5fc1e41d38dd486bb2101ef0df8c8705
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102890- (2022)
Human mouse chimeric models are valuable tools to develop in-vivo disease models. However, in-vivo detection of human cells limits their analysis. To facilitate in-vivo modeling of Down syndrome (DS), we generated a stable AAVS1-EGFP isogenic pair of
Externí odkaz:
https://doaj.org/article/a4a16b0d66524ffaba7f2f4f12e47c26
Publikováno v:
Stem Cell Research, Vol 61, Iss , Pp 102771- (2022)
Human-induced pluripotent stem cells (hiPSCs) clones NSi001-A, NSi001-B, and NSi001-C were generated from a female individual of Indian origin having Robertsonian translocation down syndrome (DS) by reprogramming peripheral blood mononuclear cells (P
Externí odkaz:
https://doaj.org/article/805c3e82041d4910a6d796bd8baca472