Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sunita Midha"'
Autor:
Sunita Midha, Clifford B. Longley, Kiho Han, Helena R. Axelrod, Arthur A. Branstrom, Eugene R. Baizman
Publikováno v:
Analytical Biochemistry. 280:315-319
Bacterial peptidoglycan synthesis is a well-characterized system for targeting new antimicrobial drugs. Formation of the peptidoglycan precursors Lipid I and Lipid II is catalyzed by the gene products of mraY and murG, which are involved in the first
Autor:
Rui Liang, Chunguang Wang, Kiho Han, Nicole T. Hatzenbuhler, Buwen Huang, Muthoni G. Kamau, Helena R. Axelrod, Jan A. Anderson, Ramesh Kakarla, Neil Bristol, Anna Chen, Domingos J. Silva, Arthur Branstrom, Robert D. Goldman, Richard G. Dulina, Huiming Wang, Feng Chi, David Gange, Clifford B. Longley, Michael J. Sofia, Nigel M. Allanson, Dashan Liu, Rakesh K. Jain, Eugene R. Baizman, Natan A. Kogan, Sunita Midha
Publikováno v:
Journal of Medicinal Chemistry. 42:3193-3198
The increase in bacterial resistance to conventional chemotherapy has resulted in a resurgent interest in the discovery and development of antibacterial agents.1-4 The search for novel antibiotics active against resistant phenotypes is increasingly f
Autor:
Babu Suresh D, Leigh Wierichs, Suzanne Walker, Natan A. Kogan, Michael J. Sofia, Karen Bruker, Ramesh Kakarla, Helena R. Axelrod, Clifford B. Longley, Sunita Midha, Daniel Kahne
Publikováno v:
Proceedings of the National Academy of Sciences. 93:1585-1590
A promising class of compounds for DNA transfection have been designed by conjugating various polyamines to bile-acid-based amphiphiles. Formulations containing these compounds were tested for their ability to facilitate the uptake of a beta-galactos
Publikováno v:
Analytical biochemistry. 333(2)
A new protein affinity purification system has been developed. Recombinant tobacco mosaic virus (TMV) was used as an affinity matrix for isolation and purification of the given protein of interest. In model experiments, streptavidin-specific heptapep
Publikováno v:
FEMS microbiology letters. 191(2)
An in situ transglycosylase assay has been developed using endogenously synthesized lipid II. The assay involves the preferential synthesis and accumulation of lipid II in a reaction mixture containing the cell wall membrane material isolated from Es