Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sunita, Sridhar"'
Autor:
Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin Hübner, Abhijit Chakraborty, Meghana Pagadala, Rosalind Bump, Sahaana Chandran, Katerina Kraft, Rocio Acuna-Hidalgo, Derek Reid, Kristin Sikkink, Monika Mauermann, Edwin F. Juarez, Anne Jenseit, James T. Robinson, Kristian W. Pajtler, Till Milde, Natalie Jäger, Petra Fiesel, Ling Morgan, Sunita Sridhar, Nicole G. Coufal, Michael Levy, Denise Malicki, Charlotte Hobbs, Stephen Kingsmore, Shareef Nahas, Matija Snuderl, John Crawford, Robert J. Wechsler-Reya, Tom Belle Davidson, Jennifer Cotter, George Michaiel, Gudrun Fleischhack, Stefan Mundlos, Anthony Schmitt, Hannah Carter, Kulandaimanuvel Antony Michealraj, Sachin A. Kumar, Michael D. Taylor, Jeremy Rich, Frank Buchholz, Jill P. Mesirov, Stefan M. Pfister, Ferhat Ay, Jesse R. Dixon, Marcel Kool, Lukas Chavez
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Ependymoma is a tumor of the brain or spinal cord. The two most common and aggressive molecular groups of ependymoma are the supratentorial ZFTA-fusion associated and the posterior fossa ependymoma group A. In both groups, tumors occur mainl
Externí odkaz:
https://doaj.org/article/7c75228f7b794031a963791639822393
Autor:
Sunita, Sridhar, Megan Rose, Paul, Lanipua, Yeh-Nayre, Paritosh C, Khanna, Jennifer, Elster, Paula, Aristizabal, John R, Crawford
Publikováno v:
Journal of Pediatric Hematology/Oncology. 45:e21-e25
Bevacizumab-based therapies have been utilized as single or combination therapy of refractory/recurrent pediatric low-grade gliomas. Its efficacy for symptomatic cervicomedullary low-grade gliomas (cmLGGs) in the upfront and the recurrent setting is
Publikováno v:
Pediatrics In Review. 42:514-518
1. Kathleen Lo, MD* 2. Sunita Sridhar, MD* 3. Sabina Ali, MD† 1. *Department of Pediatrics and 2. †Department of Pediatric Gastroenterology, University of California San Francisco Benioff Children’s Hospital Oakland, Oakland, CA An 18-month-old
Publikováno v:
Neuro-Oncology. 24:i121-i122
Extrachromosomal circular DNA (ecDNA) is an important driver of aggressive cancers, including medulloblastoma (MB), the most common malignant pediatric brain tumor. Our study’s aim is to better understand how ecDNA containing cells can potentiate m
Autor:
Robert J. Wechsler-Reya, Siavash R. Dehkordi, James T. Robinson, Meghana Pagadala, Miriam Adam, Jesse R. Dixon, Vineet Bafna, Joshua T. Lange, Edwin F. Juarez, Shanqing Wang, Hannah Carter, Ivy Tsz-Lo Wong, Michael J. Levy, Sunita Sridhar, Sameena Wani, Ashutosh Tiwari, Sahaana Chandran, Owen Chapman, Richard H. Scheuermann, John Robertson Crawford, Jens Luebeck, Ernest Fraenkel, Paul S. Mischel, Scott L. Pomeroy, Lukas Chavez, Jon D. Larson, Denise M. Malicki, Nicole G. Coufal, Yingxi Lin, Jeremy N. Rich, Jill P. Mesirov
SUMMARYExtrachromosomal circular DNA (ecDNA) is an important driver of aggressive tumor growth, promoting high oncogene copy number, intratumoral heterogeneity, accelerated evolution of drug resistance, enhancer rewiring, and poor outcome. ecDNA has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2151d0b16a9efd4796910338cc6de331
https://doi.org/10.1101/2021.10.18.464907
https://doi.org/10.1101/2021.10.18.464907
EPCO-45. EXTRACHROMOSOMAL DNA PROMOTES ONCOGENE AMPLIFICATION ACROSS MULTIPLE PEDIATRIC CANCER TYPES
Publikováno v:
Neuro-Oncology. 24:vii126-vii126
Extrachromosomal circular DNA (ecDNA) is an important driver of aggressive cancers. Its frequency and impact on pediatric cancers has yet to be fully described. To determine the ecDNA prevalence in various pediatric cancer types, we accessed whole ge
Publikováno v:
Neuro-Oncology. 24:vii157-vii157
Extrachromosomal circular DNA (ecDNA) is an important driver of aggressive cancers, including medulloblastoma (MB), the most common pediatric brain tumor. To assess the clinical importance of ecDNA in MB, we applied computational methods to detect ec
Autor:
Owen Chapman, Sunita Sridhar, Jon D. Larson, Robert J. Wechsler-Reya, Jill Mesirov, Lukas Chavez
Publikováno v:
Cancer Research. 82:6214-6214
Extrachromosomal circular DNA (ecDNA) is an important driver of aggressive cancers, including medulloblastoma (MB), the most common malignant pediatric brain tumor. To assess the clinical import of ecDNA in MB, we applied computational methods to det
Autor:
Owen Chapman, Sunita Sridhar, Shanqing Wang, Jon Larson, Robert Wechsler-Reya, Jill Mesirov, Lukas Chavez
Publikováno v:
Neuro-Oncology. 24:i112-i112
Extrachromosomal circular DNA (ecDNA) is an important driver of aggressive cancers, including medulloblastoma (MB), the most common malignant pediatric brain tumor. To assess the clinical importance of ecDNA in MB, we applied computational methods to
Publikováno v:
Open Forum Infectious Diseases
Background Levofloxacin prophylaxis in pediatric oncology patients with chemotherapy-induced severe prolonged neutropenia has been shown to reduce risk for febrile neutropenia and systemic infections. With increased use of prophylaxis there is concer