Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Sunita, Sinha"'
Autor:
Marcia Smiti Jude, Chen Xi Yang, Fernando Studart Leitao Filho, Ana I. Hernandez Cordero, Julia Yang, Tawimas Shaipanich, Xuan Li, David Lin, Julie MacIsaac, Michael S. Kobor, Sunita Sinha, Corey Nislow, Amrit Singh, Wan Lam, Stephen Lam, Silvia Guillemi, Marianne Harris, Julio Montaner, Raymond T. Ng, Christopher Carlsten, S. F. Paul Man, Don D. Sin, Janice M. Leung
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background People living with HIV (PLWH) are at increased risk of developing Chronic Obstructive Pulmonary Disease (COPD) independent of cigarette smoking. We hypothesized that dysbiosis in PLWH is associated with epigenetic and transcriptom
Externí odkaz:
https://doaj.org/article/3bbc99c6afb9461b8675959190300c9f
Autor:
Davide Tortora, Morgan E. Roberts, Gunjan Kumar, Sudha S. Kotapalli, Elie Ritch, Joshua M. Scurll, Brian McConeghy, Sunita Sinha, Alexander W. Wyatt, Peter C. Black, Mads Daugaard
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106525- (2023)
Summary: Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor central in the regulation of key cellular processes including cell metabolism, tissue differentiation, and regulation of the immune system. PPARγ is required fo
Externí odkaz:
https://doaj.org/article/f77ff7431c4342bdb81350390eef33b5
Autor:
Søs Skovsø, Evgeniy Panzhinskiy, Jelena Kolic, Haoning Howard Cen, Derek A. Dionne, Xiao-Qing Dai, Rohit B. Sharma, Lynda Elghazi, Cara E. Ellis, Katharine Faulkner, Stephanie A. M. Marcil, Peter Overby, Nilou Noursadeghi, Daria Hutchinson, Xiaoke Hu, Hong Li, Honey Modi, Jennifer S. Wildi, J. Diego Botezelli, Hye Lim Noh, Sujin Suk, Brian Gablaski, Austin Bautista, Ryekjang Kim, Corentin Cras-Méneur, Stephane Flibotte, Sunita Sinha, Dan S. Luciani, Corey Nislow, Elizabeth J. Rideout, Eric N. Cytrynbaum, Jason K. Kim, Ernesto Bernal-Mizrachi, Laura C. Alonso, Patrick E. MacDonald, James D. Johnson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Insulin receptor protein is present in pancreatic β-cells, but the consequences of β-cell insulin resistance are incompletely understood. Here the authors use a combination of mouse studies and mathematical modelling to show that loss of beta-cell
Externí odkaz:
https://doaj.org/article/34fcff15f65143fa8ca0bab84b4cd93e
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-12 (2021)
Abstract Melanoma originates from melanin-producing cells called melanocytes. Melanoma poses a great risk because of its rapid ability to spread and invade new organs. Cellular metastasis involves alteration in the gene expression profile and their t
Externí odkaz:
https://doaj.org/article/1234a88590d64b19b0ce66a8ef193429
Autor:
Adam Doelman, Seth Tigchelaar, Brian McConeghy, Sunita Sinha, Martin S. Keung, Neda Manouchehri, Megan Webster, Shera Fisk, Charlotte Morrison, Femke Streijger, Corey Nislow, Brian K. Kwon
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract Background The gut microbiome is a diverse network of bacteria which inhabit our digestive tract and is crucial for efficient cellular metabolism, nutrient absorption, and immune system development. Spinal cord injury (SCI) disrupts autonomi
Externí odkaz:
https://doaj.org/article/f9383aabaec847a3b3a54c825046071c
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Receptor for advanced glycation end products (RAGE) is a multi-ligand transmembrane receptor of the immunoglobulin superfamily. Lysophosphatidic acid (LPA) is a ligand for RAGE and is involved in physiological and pathophysiologic
Externí odkaz:
https://doaj.org/article/6d6c3bf9a23643629c03ed1ace61a4c6
Autor:
Stella Xu, Amy Tsai, Marc A. Sze, Emily A. Vucic, Tawimas Shaipanich, Marianne Harris, Silvia Guillemi, Julia Yang, Sunita Sinha, Corey Nislow, Julio Montaner, Wan Lam, Stephen Lam, Don D. Sin, S. F. Paul Man, Janice M. Leung
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Persons living with human immunodeficiency virus (PLWH) face an increased burden of chronic obstructive pulmonary disease (COPD). Repeated pulmonary infections, antibiotic exposures, and immunosuppression may contribute to an alte
Externí odkaz:
https://doaj.org/article/966d15fb74fc49cf8f5994bc41c6ca86
Autor:
Adam Doelman, Seth Tigchelaar, Brian McConeghy, Sunita Sinha, Martin S. Keung, Neda Manouchehri, Megan Webster, Shera Fisk, Charlotte Morrison, Femke Streijger, Corey Nislow, Brian K. Kwon
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/f6e9df9bf36c43e08264597fbffc9427
Autor:
Cene Gostinčar, Jason E. Stajich, Anja Kejžar, Sunita Sinha, Corey Nislow, Metka Lenassi, Nina Gunde-Cimerman
Publikováno v:
Journal of Fungi, Vol 7, Iss 9, p 723 (2021)
The experimental evolution of microorganisms exposed to extreme conditions can provide insight into cellular adaptation to stress. Typically, stress-sensitive species are exposed to stress over many generations and then examined for improvements in t
Externí odkaz:
https://doaj.org/article/17444f9fcdf241119cd04223325a430d
Autor:
Sunita Sinha, Stephane Flibotte, Mauricio Neira, Sean Formby, Ana Plemenitaš, Nina Gunde Cimerman, Metka Lenassi, Cene Gostinčar, Jason E. Stajich, Corey Nislow
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 7, Pp 2015-2022 (2017)
Extremophilic organisms demonstrate the flexibility and adaptability of basic biological processes by highlighting how cell physiology adapts to environmental extremes. Few eukaryotic extremophiles have been well studied and only a small number are a
Externí odkaz:
https://doaj.org/article/c8e6274e51d14267999ad6b5c8a670b4