Macrophages and inflammatory mediators in pulmonary injury induced by mustard vesicants

Autor: Malaviya, R, Sunil, Vr, Venosa, A, Vayas, Kn, Businaro, Rita, Heck, De, Laskin, Jd, Laskin, D. l.

Publikováno v: Annals of the New York Academy of Sciences. 1374(1)

Sulfur mustard (SM) and nitrogen mustard (NM) are cytotoxic alkylating agents that cause severe and progressive injury to the respiratory tract, resulting in significant morbidity and mortality. Evidence suggests that macrophages and the inflammatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::817bbb74df0ab59a3a68345567299da6
https://pubmed.ncbi.nlm.nih.gov/27351588

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Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats.

Autor: Cary CM; Department of Pharmacology and Toxicology Ernest Mario School of Pharmacy, Environmental and Occupational Health Sciences Institute, Rutgers University, 170 Frelinghuysen Road, 08854, Piscataway, NJ, USA., Seymore TN; Department of Pharmacology and Toxicology Ernest Mario School of Pharmacy, Environmental and Occupational Health Sciences Institute, Rutgers University, 170 Frelinghuysen Road, 08854, Piscataway, NJ, USA., Singh D; Center for Nanotechnology and Nanotoxicology, Department of Environmental Health, Harvard T. H. Chan School of Public Health, Harvard University, 02115, Boston, MA, USA.; Environmental and Occupational Health Sciences Institute (EOHSI), 08854, Piscataway, NJ, USA., Vayas KN; Department of Pharmacology and Toxicology Ernest Mario School of Pharmacy, Environmental and Occupational Health Sciences Institute, Rutgers University, 170 Frelinghuysen Road, 08854, Piscataway, NJ, USA., Goedken MJ; Research Pathology Services, Rutgers University, 08854, Piscataway, NJ, USA., Adams S; Department of Pharmacology and Toxicology Ernest Mario School of Pharmacy, Environmental and Occupational Health Sciences Institute, Rutgers University, 170 Frelinghuysen Road, 08854, Piscataway, NJ, USA., Polunas M; Research Pathology Services, Rutgers University, 08854, Piscataway, NJ, USA., Sunil VR; Department of Pharmacology and Toxicology Ernest Mario School of Pharmacy, Environmental and Occupational Health Sciences Institute, Rutgers University, 170 Frelinghuysen Road, 08854, Piscataway, NJ, USA., Laskin DL; Department of Pharmacology and Toxicology Ernest Mario School of Pharmacy, Environmental and Occupational Health Sciences Institute, Rutgers University, 170 Frelinghuysen Road, 08854, Piscataway, NJ, USA.; Environmental and Occupational Health Sciences Institute (EOHSI), 08854, Piscataway, NJ, USA., Demokritou P; Center for Nanotechnology and Nanotoxicology, Department of Environmental Health, Harvard T. H. Chan School of Public Health, Harvard University, 02115, Boston, MA, USA.; Environmental and Occupational Health Sciences Institute (EOHSI), 08854, Piscataway, NJ, USA.; Department of Environmental and Occupational Health and Justice, Rutgers School of Public Health, Rutgers University, 08854, Piscataway, NJ, USA., Stapleton PA; Department of Pharmacology and Toxicology Ernest Mario School of Pharmacy, Environmental and Occupational Health Sciences Institute, Rutgers University, 170 Frelinghuysen Road, 08854, Piscataway, NJ, USA. stapleton@eohsi.rutgers.edu.; Environmental and Occupational Health Sciences Institute (EOHSI), 08854, Piscataway, NJ, USA. stapleton@eohsi.rutgers.edu.

Publikováno v: Particle and fibre toxicology [Part Fibre Toxicol] 2023 Apr 23; Vol. 20 (1), pp. 16. Date of Electronic Publication: 2023 Apr 23.

Microvesicle-Derived miRNAs Regulate Proinflammatory Macrophage Activation in the Lung Following Ozone Exposure.

Autor: Carnino JM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, School of Medicine, Boston University, Boston, Massachusetts 02118, USA., Lee H; Division of Pulmonary and Critical Care Medicine, Department of Medicine, School of Medicine, Boston University, Boston, Massachusetts 02118, USA., Smith LC; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey 08854, USA., Sunil VR; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey 08854, USA., Rancourt RC; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey 08854, USA., Vayas K; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey 08854, USA., Cervelli J; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey 08854, USA., Kwok ZH; Division of Pulmonary and Critical Care Medicine, Department of Medicine, School of Medicine, Boston University, Boston, Massachusetts 02118, USA., Ni K; Division of Pulmonary and Critical Care Medicine, Department of Medicine, School of Medicine, Boston University, Boston, Massachusetts 02118, USA., Laskin JD; Department of Environmental and Occupational Health and Justice, School of Public Health, Rutgers University, Piscataway, New Jersey 08854, USA., Jin Y; Division of Pulmonary and Critical Care Medicine, Department of Medicine, School of Medicine, Boston University, Boston, Massachusetts 02118, USA., Laskin DL; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey 08854, USA.

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2022 Apr 26; Vol. 187 (1), pp. 162-174.