Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Sunil V, Sharma"'
Autor:
Sunil V. Sharma, Xiaoxue Tong, Cristina Pubill-Ulldemolins, Christopher Cartmell, Emma J. A. Bogosyan, Emma J. Rackham, Enrico Marelli, Refaat B. Hamed, Rebecca J. M. Goss
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Coupling synthetic biology and chemical reactions in cells is a challenging task. The authors engineer bacteria capable of generating bromo-metabolites, develop a mild Suzuki-Miyaura cross-coupling reaction compatible with cell growth and carry out t
Externí odkaz:
https://doaj.org/article/345055a2bdf74d8e90c9a96c8f5dc70e
Autor:
Jennifer Hiras, Sunil V. Sharma, Vidhyavathi Raman, Ryan A. J. Tinson, Miriam Arbach, Dominic F. Rodrigues, Javiera Norambuena, Chris J. Hamilton, Thomas E. Hanson
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT Low-molecular-weight (LMW) thiols mediate redox homeostasis and the detoxification of chemical stressors. Despite their essential functions, the distribution of LMW thiols across cellular life has not yet been defined. LMW thiols are also th
Externí odkaz:
https://doaj.org/article/d36b29d461834c37bfe7f6803e0f1170
The authors would like to acknowledge the financial assistance of the UEA (CHE43.3.60), the EU Interreg Manche/Channel cross-border projects Innovative Synthesis: Chemistry and Entrepreneurship (IS:CE-chem: ref. 4061) and ‘Academy-Industry chemistr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a163952edc01121a5821c27e18ada0e7
https://ueaeprints.uea.ac.uk/id/eprint/91644/
https://ueaeprints.uea.ac.uk/id/eprint/91644/
Autor:
Archana Sharma, Diksha Sharma, Neha Saini, Sunil V. Sharma, Vijay Kumar Thakur, Ramesh K. Goyal, Prabodh Chander Sharma
Funding: SERB-DST (Science and Engineering Research Board-Department of Science and Technology), Govt. of India, is duly acknowledged for financial assistance under Fast Track Scheme For Young Scientist (to Dr. Prabodh Chander Sharma) video file No.:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e1c90c1abccb68407db946e991daef
https://hdl.handle.net/10023/27728
https://hdl.handle.net/10023/27728
Autor:
Rebecca J. M. Goss, Samuel Molyneux, Helen Connaris, Ying Zhang, Charlotte Crowe, Danai S. Gkotsi, Sunil V. Sharma
Publikováno v:
Chemical Society Reviews
The enzymatic generation of carbon–halogen bonds is a powerful strategy used by both nature and synthetic chemists to tune the bioactivity, bioavailability and reactivity of compounds, opening up the opportunity for selective C–H functionalisatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7faf77d8994fbff639479937968612
http://europepmc.org/articles/PMC8407142
http://europepmc.org/articles/PMC8407142
Publikováno v:
Organic Chemistry Frontiers
The development of mild, aqueous conditions for the cross-coupling of highly functionalized (hetero)aryl chlorides or bromides is attractive, enabling their functionalization and diversification. Herein, we report a general method for Suzuki–Miyaur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3379fd5eed156a7577d68835aeeb9377
https://doi.org/10.1039/d1qo00919b
https://doi.org/10.1039/d1qo00919b
Autor:
Simon J. Moore, Rosemary Lynch, Rebecca J. M. Goss, Soo Mei Chee, Rhodri M. L. Morgan, Hung-En Lai, Karen M. Polizzi, Paul S. Freemont, Sunil V. Sharma, Alan M. C. Obled
Publikováno v:
ACS Chemical Biology
H.E.L. was supported by an Imperial College President’s Ph.D. Scholarship. We thank UKRI EPSRC (EP/K038648/1, EP/L011573/1 to P.S.F.) and the European Union’s Seventh Framework Programme (FP7/2007–2013/ERC grant agreement no. 614779 GenoChemeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d3ed9c93b06e2c411d47e6ff52b851
https://pubmed.ncbi.nlm.nih.gov/34648268
https://pubmed.ncbi.nlm.nih.gov/34648268
Autor:
Rosemary Lynch, Sunil V. Sharma, Bertolt Gust, Antoine Abou Fayad, Christopher Cartmell, Rebecca J. M. Goss, Nils Hauck
Publikováno v:
Chembiochem
A nonenzymatic Pictet‐Spengler reaction has been postulated to give rise to a subset of naturally occurring uridyl peptide antibiotics (UPAs). Here, using a combination of strain engineering and synthetic chemistry, we demonstrate that Pictet‐Spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9008f67123c6bc0ab6b338bf37a1dc40
https://hdl.handle.net/10023/21275
https://hdl.handle.net/10023/21275
Autor:
Alexandra M. Z. Slawin, Rebecca J. M. Goss, Freideriki Michailidou, Murray J. B. Brown, Sunil V. Sharma, Tomas Lebl
Publikováno v:
Molecules
Volume 25
Issue 23
Molecules, Vol 25, Iss 5513, p 5513 (2020)
Volume 25
Issue 23
Molecules, Vol 25, Iss 5513, p 5513 (2020)
Fluorinated nucleoside analogues have attracted much attention as anticancer and antiviral agents and as probes for enzymatic function. However, the lack of direct synthetic methods, especially for 2&prime
3&prime
dideoxy-2&prime
diflu
3&prime
dideoxy-2&prime
diflu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a6437e9a552d4d8de87ed0b1d3112c
Autor:
Sunil V. Sharma, Steven G. Van Lanen, Rebecca J. M. Goss, David Burnett, Freideriki Michailidou
The uridyl peptide antibiotics are a class of structurally and biologically diverse series of pyrimidine containing natural products, that have attracted considerable interest due to their powerful and varied bioactivities; and potential for exploita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f8cff1c76ebd16ebd6e67ac123ba4ad
https://doi.org/10.1016/b978-0-12-409547-2.14797-3
https://doi.org/10.1016/b978-0-12-409547-2.14797-3