Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Sunil S, Raikar"'
Autor:
Hope L. Mumme, Sunil S. Raikar, Swati S. Bhasin, Beena E. Thomas, Taylor Lawrence, Elizabeth P. Weinzierl, Yakun Pang, Deborah DeRyckere, Chuck Gawad, Daniel S. Wechsler, Christopher C. Porter, Sharon M. Castellino, Douglas K. Graham, Manoj Bhasin
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)
Abstract Background Mixed phenotype acute leukemia (MPAL), a rare subgroup of leukemia characterized by blast cells with myeloid and lymphoid lineage features, is difficult to diagnose and treat. A better characterization of MPAL is essential to unde
Externí odkaz:
https://doaj.org/article/27b0d44d90b644919eac2539e49cde72
Autor:
Hope Mumme, Beena E. Thomas, Swati S. Bhasin, Upaasana Krishnan, Bhakti Dwivedi, Pruthvi Perumalla, Debasree Sarkar, Gulay B. Ulukaya, Himalee S. Sabnis, Sunita I. Park, Deborah DeRyckere, Sunil S. Raikar, Melinda Pauly, Ryan J. Summers, Sharon M. Castellino, Daniel S. Wechsler, Christopher C. Porter, Douglas K. Graham, Manoj Bhasin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Acute myeloid leukemia (AML) microenvironment exhibits cellular and molecular differences among various subtypes. Here, we utilize single-cell RNA sequencing (scRNA-seq) to analyze pediatric AML bone marrow (BM) samples from diagnosis (Dx),
Externí odkaz:
https://doaj.org/article/a3787863b5cb43ff9dcb50ae8a436b4d
Autor:
Swati S. Bhasin, Beena E. Thomas, Ryan J. Summers, Debasree Sarkar, Hope Mumme, William Pilcher, Mohamed Emam, Sunil S. Raikar, Sunita I. Park, Sharon M. Castellino, Douglas K. Graham, Manoj K. Bhasin, Deborah DeRyckere
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Different driver mutations and/or chromosomal aberrations and dysregulated signaling interactions between leukemia cells and the immune microenvironment have been implicated in the development of T-cell acute lymphoblastic leukemia (T-ALL).
Externí odkaz:
https://doaj.org/article/bad7ef4e0fc14a73bb94f1c5d3d5576c
Autor:
Scott A. Becker, Brian G. Petrich, Bing Yu, Kristopher A. Knight, Harrison C. Brown, Sunil S. Raikar, Christopher B. Doering, H. Trent Spencer
Publikováno v:
Molecular Therapy: Oncolytics, Vol 29, Iss , Pp 145-157 (2023)
Adoptive cell therapy (ACT) utilizing γδ T cells is becoming a promising option for the treatment of cancer, because it offers an off-the-shelf allogeneic product that is safe, potent, and clinically effective. Approaches to engineer or enhance imm
Externí odkaz:
https://doaj.org/article/53f3291d08774bab9a7136bad26a24d2
Autor:
Navdeep Jhita, Sunil S. Raikar
Publikováno v:
Exploration of Immunology, Vol 2, Iss 3, Pp 334-350 (2022)
Cancer immunotherapy, especially T-cell driven targeting, has significantly evolved and improved over the past decade, paving the way to treat previously refractory cancers. Hematologic malignancies, given their direct tumor accessibility and less im
Externí odkaz:
https://doaj.org/article/4b2caa6ee8644724a0a2928e275eb891
Autor:
Miyoung Lee, Jamie A. G. Hamilton, Ganesh R. Talekar, Anthony J. Ross, Langston Michael, Manali Rupji, Bhakti Dwivedi, Sunil S. Raikar, Jeremy Boss, Christopher D. Scharer, Douglas K. Graham, Deborah DeRyckere, Christopher C. Porter, Curtis J. Henry
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Obesity has been reported to promote tumourigenesis and chemoresistance but the underlying mechanisms are not completely understood. Here, the authors show that adipocytes induce Galectin-9 (GAL-9) expression in B-acute lymphoblastic leukaemia (B-ALL
Externí odkaz:
https://doaj.org/article/2dbae7c4d3ee43d79487bfe5ab1bc1e6
Autor:
Shireen S. Ganapathi, Sunil S. Raikar, Svetlana A. Yatsenko, Miroslav Djokic, Andrew Bukowinski
Publikováno v:
Cancer Reports, Vol 4, Iss 4, Pp n/a-n/a (2021)
Abstract Background Mixed phenotype acute leukemia (MPAL) is a rare subset of acute leukemia in the pediatric population associated with genetic alterations seen in both acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Case We des
Externí odkaz:
https://doaj.org/article/f6d38d946bf246e8a2fc2f35f194fb88
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-21 (2019)
Abstract Chimeric antigen receptor (CAR) T cell therapy has been successful in treating B cell malignancies in clinical trials; however, fewer studies have evaluated CAR T cell therapy for the treatment of T cell malignancies. There are many challeng
Externí odkaz:
https://doaj.org/article/ca5ec1be84d64cb4b135e517193402cd
Autor:
Lacey A. Birnbaum, Emily C. Sullivan, Priscilla Do, Biaggio Uricoli, Sunil S. Raikar, Christopher C. Porter, Curtis J. Henry, Erik C. Dreaden
Publikováno v:
Biomacromolecules. 24:1164-1172
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a0d44aca3f76a716e4dc6296cee88d5
https://doi.org/10.1021/acs.biomac.2c01207
https://doi.org/10.1021/acs.biomac.2c01207
Autor:
Juhi Jain, Elizabeth P. Weinzierl, Debra Saxe, John Bergsagel, Jason Gotlib, Andreas Reiter, Sunil S. Raikar
Publikováno v:
HemaSphere, Vol 4, Iss 6, p e486 (2020)
Externí odkaz:
https://doaj.org/article/7a74b3d6d388425389e9f07b567c3247