Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Sunil R, Hingorani"'
Autor:
Andrés M. Arias-Lorza, James R. Costello, Sunil R. Hingorani, Daniel D. Von Hoff, Ronald L. Korn, Natarajan Raghunand
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Pre-clinical and clinical studies have shown that PEGPH20 depletes intratumoral hyaluronic acid (HA), which is linked to high interstitial fluid pressures and poor distribution of chemotherapies. 29 patients with metastatic advanced solid tu
Externí odkaz:
https://doaj.org/article/efc4f39a74d3420ca38b41a64d4c8737
Autor:
Philip D Greenberg, Patrick Bonson, Sunil R Hingorani, Ayaka Hulbert, Meagan R Rollins, Ryan S Basom, Jeffrey Delrow, Adam L Burrack
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background Achieving robust responses with adoptive cell therapy for the treatment of the highly lethal pancreatic ductal adenocarcinoma (PDA) has been elusive. We previously showed that T cells engineered to express a mesothelin-specific T cell rece
Externí odkaz:
https://doaj.org/article/0ce5efbe9025488eb29b3b4f114e582e
Autor:
Sunil R. Hingorani
Publikováno v:
Nature Reviews Cancer. 23:57-77
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::855097cfcb97a8e929916e613eb174df
https://doi.org/10.1038/s41568-022-00530-w
https://doi.org/10.1038/s41568-022-00530-w
Autor:
Nithya Kartha, Jessica E. Gianopulos, Zachary Schrank, Sarah M. Cavender, Stephanie Dobersch, Bryan D. Kynnap, Adrianne Wallace-Povirk, Cynthia L. Wladyka, Juan F. Santana, Jaeseung C. Kim, Angela Yu, Caroline M. Bridgwater, Kathrin Fuchs, Sarah Dysinger, Aaron E. Lampano, Faiyaz Notta, David H. Price, Andrew C. Hsieh, Sunil R. Hingorani, Sita Kugel
Publikováno v:
Science Translational Medicine. 15
Pancreatic ductal adenocarcinoma (PDAC) is classified into two key subtypes, classical and basal, with basal PDAC predicting worse survival. Using in vitro drug assays, genetic manipulation experiments, and in vivo drug studies in human patient-deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e91f327ee950b64d338872da3484619a
https://doi.org/10.1126/scitranslmed.abn9674
https://doi.org/10.1126/scitranslmed.abn9674
Autor:
Mara H. Sherman, Sunil R. Hingorani, Zheng Xia, David W. Dawson, Rosemary Makar, Ariana Sattler, Jennifer M. Finan, Wesley Horton, Hannah Sanford-Crane, Sohinee Bhattacharyya, Chet Oon, M. Kathrina Onate, Duanchen Sun, Christopher C. DuFort, R. Crystal Chaw, Mark W. Berry, Erin J. Helms
Figures S1-S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b112d10e84ebce7c91631d5ef2348c58
https://doi.org/10.1158/2159-8290.22541218.v1
https://doi.org/10.1158/2159-8290.22541218.v1
Autor:
Sunil R. Hingorani, Philip D. Greenberg, Robert H. Pierce, Ellen J. Spartz, Jackson F. Raynor, J. Scott Brockenbrough, Cheryl Black, Patrick Bonson, Ayaka Hulbert, Adam L. Burrack, Ingunn M. Stromnes
Supplementary Figures 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3889d98b8d31697f6a7b46d07e3a0c8
https://doi.org/10.1158/2326-6066.22542532
https://doi.org/10.1158/2326-6066.22542532
Autor:
Mara H. Sherman, Sunil R. Hingorani, Zheng Xia, David W. Dawson, Rosemary Makar, Ariana Sattler, Jennifer M. Finan, Wesley Horton, Hannah Sanford-Crane, Sohinee Bhattacharyya, Chet Oon, M. Kathrina Onate, Duanchen Sun, Christopher C. DuFort, R. Crystal Chaw, Mark W. Berry, Erin J. Helms
Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac7a9dea48b0cdc96253da662ba9a7c
https://doi.org/10.1158/2159-8290.22541209
https://doi.org/10.1158/2159-8290.22541209
Autor:
Mara H. Sherman, Sunil R. Hingorani, Zheng Xia, David W. Dawson, Rosemary Makar, Ariana Sattler, Jennifer M. Finan, Wesley Horton, Hannah Sanford-Crane, Sohinee Bhattacharyya, Chet Oon, M. Kathrina Onate, Duanchen Sun, Christopher C. DuFort, R. Crystal Chaw, Mark W. Berry, Erin J. Helms
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8dd46fbe44a5dc65d23631c94040de
https://doi.org/10.1158/2159-8290.22541215
https://doi.org/10.1158/2159-8290.22541215
Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy resistant to most therapies, including immune checkpoint blockade. To elucidate mechanisms of immunotherapy resistance, we assessed immune parameters in resected human PDA. We demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895178183e66c16663a21cacee18e29e
https://doi.org/10.1158/2326-6066.c.6548098
https://doi.org/10.1158/2326-6066.c.6548098
S1. TLS composition and immunological features of resected PDA. S2. Gating strategy for analyzing CD244 (2B4) and Tim3 expression on CD8 T cells in blood of normal individuals (Nl), in blood of PDA patients (PDA blood) and in tumors. S3. Representati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06975f8af564a22c70310cf51b1ed41f
https://doi.org/10.1158/2326-6066.22536277.v1
https://doi.org/10.1158/2326-6066.22536277.v1