Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sunil Muthusami"'
Autor:
Shraddha Mittal, Sunil Muthusami, Lauren Marlowe, Sheila Knerr, Julianne Prasto, Tiffany Anise Cooke, Jacek Bochenski, Michael A. Horst
Publikováno v:
Pediatric Emergency Care. 38:43-47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e32ab05129c9374e5e44141a3baa1023
https://doi.org/10.1097/pec.0000000000002601
https://doi.org/10.1097/pec.0000000000002601
Autor:
Glenn Dorsam, Meixian Xiang, Hisham Abdel-Azim, Yali Ding, Olivia L. Francis, Liangxue Lai, Sunil Muthusami, Hongsheng Ouyang, Zheng Ge, Sinisa Dovat, Xiaokang Pan, Kimberly J. Payne, Haijun Wang, Mansi Sachdev, Chunhua Song, Bi-Hua Tan, Chandrika Gowda, Christopher L. Morris
Publikováno v:
Journal of Biological Chemistry. 291:4004-4018
Impaired function of the Ikaros (IKZF1) protein is associated with the development of high-risk B-cell precursor acute lymphoblastic leukemia (B-ALL). The mechanisms of Ikaros tumor suppressor activity in leukemia are unknown. Ikaros binds to the ups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4763796e90d64ad694c42abe0388905
https://doi.org/10.1074/jbc.m115.679332
https://doi.org/10.1074/jbc.m115.679332
Autor:
Mansi Sachdev, Dhimant Desai, Sinisa Dovat, Krishne Gowda, Chunhua Song, Raghavendra Gowda, Kimberly J. Payne, Markus Müschen, Zheng Ge, Xiaokang Pan, Chandrika Gowda, Sunil Muthusami, Gavin P. Robertson, Hilde Schjerven, Yongqing Tong, Shantu Amin, Yali Ding, Haijun Wang, Bi-Hua Tan
Publikováno v:
Blood. 126:1813-1822
Ikaros (IKZF1) is a tumor suppressor that binds DNA and regulates expression of its target genes. The mechanism of Ikaros activity as a tumor suppressor and the regulation of Ikaros function in leukemia are unknown. Here, we demonstrate that Ikaros c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60e39ccc13d3d8610cb701c7426b194
https://doi.org/10.1182/blood-2015-06-651505
https://doi.org/10.1182/blood-2015-06-651505
Autor:
Sinisa Dovat, Jonathon L. Payne, Chandrika Gowda, Malika Kapadia, Sunil Muthusami, Bi-Hua Tan, Melanie Hartman, Lidija Petrovic-Dovat, Mansi Sachdev, Yali Ding, Chunhua Song
Publikováno v:
Current Pharmaceutical Design. 22:1-1
BACKGROUND Casein kinase II (CK2) is a pro-oncogenic protein, which is emerging as a promising therapeutic target in cancer. Recent studies have revealed an important role for CK2 in tumorigenesis. High levels of CK2 are noted in many malignancies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a742516ff04b88bb364af21ea199793
https://doi.org/10.2174/1381612822666161006154311
https://doi.org/10.2174/1381612822666161006154311
Autor:
Sinisa Dovat, Chandrika Gowda, Kimberly J. Payne, Chunhua Song, Sunil Muthusami, Zheng Ge, Yali Ding
Publikováno v:
Blood. 126:4800-4800
IKZF1 (Ikaros) encodes a DNA-binding protein that acts as a tumor suppressor in acute lymphoblastic leukemia. Deletion of one Ikaros allele results in the development of high-risk B-cell acute lymphoblastic leukemia (B-ALL) with a high incidence of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::628309d449b2734726e73f1a3a84669b
https://doi.org/10.1182/blood.v126.23.4800.4800
https://doi.org/10.1182/blood.v126.23.4800.4800
Publikováno v:
Indian pediatrics. 47(11)
We conducted this study to observe evidence of portal hypertension in children with visceral leishmaniasis (VL). Eighty-eight consecutive cases (50 male) of VL were subjected to ultrasonography. Those with evidence of portal hypertension also underwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c81acf3769f136c4586341bda18555
https://pubmed.ncbi.nlm.nih.gov/20453266
https://pubmed.ncbi.nlm.nih.gov/20453266
Publikováno v:
Indian journal of pediatrics. 76(8)
We report 3 cases of Visceral leishmaniasis, who presented with unusual clinical manifestations. One child was diagnosed as hemophagocytic syndrome; another masqueraded with features of leukemoid changes alongwith hemophagocytosis and trilineage myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7952c8cf4385db6fa104efe29cf8a287
https://pubmed.ncbi.nlm.nih.gov/19475352
https://pubmed.ncbi.nlm.nih.gov/19475352
Publikováno v:
Neuroscience letters. 432(3)
Objective To demonstrate the accelerated postnatal maturation/myelination in growth retarded babies compensating the deficit suffered by them during intrauterine life. Methods We studied 16 babies within the first 3 days of birth. These included 6 fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00ce630164a82c2a14b9f74c42eebe3
https://pubmed.ncbi.nlm.nih.gov/18206308
https://pubmed.ncbi.nlm.nih.gov/18206308
Autor:
Xiaokang Pan, Shantu Amin, Chunhua Song, Yali Ding, Kimberly J. Payne, Sunil Muthusami, Dhimant Desai, Sinisa Dovat, Chandrika Gowda
Publikováno v:
Cancer Research. 75:2159-2159
Ikaros (IKZF1) is a tumor suppressor whose function is impaired in high-risk pediatric B-cell acute lymphoblastic leukemia (B-ALL). IKZF1 encodes a DNA-binding, zinc finger protein that regulates expression of genes involved in important biological p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d8dfa140584b3562d9df47eabc8366e
https://doi.org/10.1158/1538-7445.am2015-2159
https://doi.org/10.1158/1538-7445.am2015-2159
Autor:
Sinisa Dovat, Xiaokang Pan, Chunhua Song, Kimberly J. Payne, Sunil Muthusami, Chandrika Gowda
Publikováno v:
Blood. 124:3571-3571
B-cell acute lymphoblastic leukemia (B-ALL) is the most common childhood leukemia. Expression profiling has identified IKZF1 (Ikaros) as a major tumor suppressor in B-ALL and established reduced Ikaros function as a poor prognostic marker for this di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e343ea6e5f55acb88f4aa0f0889de305
https://doi.org/10.1182/blood.v124.21.3571.3571
https://doi.org/10.1182/blood.v124.21.3571.3571