Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Sunil M Kurian"'
Autor:
Sunil M Kurian, Kevin Ferreri, Chia-Hao Wang, Ivan Todorov, Ismail H Al-Abdullah, Jeffrey Rawson, Yoko Mullen, Daniel R Salomon, Fouad Kandeel
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185331 (2017)
There is growing evidence that transplantation of cadaveric human islets is an effective therapy for type 1 diabetes. However, gauging the suitability of islet samples for clinical use remains a challenge. We hypothesized that islet quality is reflec
Externí odkaz:
https://doaj.org/article/660e691b568143b8911242dbfc74c4d5
Autor:
Sean E. DeWolf, Alana A. Hawkes, Sunil M. Kurian, Diana E. Gorial, Mark L. Hepokoski, Stephanie S. Almeida, Isabella R. Posner, Dianne B. McKay
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Acute kidney injury (AKI) causes distant organ dysfunction through yet unknown mechanisms, leading to multiorgan failure and death. The lungs are one of the most common extrarenal organs affected by AKI, and combined lung and kidney injury h
Externí odkaz:
https://doaj.org/article/189ac8530b42445abe063545e80ee44f
Autor:
Yevgeniy A Grigoryev, Sunil M Kurian, Zafi Avnur, Dominic Borie, Jun Deng, Daniel Campbell, Joanna Sung, Tania Nikolcheva, Anthony Quinn, Howard Schulman, Stanford L Peng, Randolph Schaffer, Jonathan Fisher, Tony Mondala, Steven Head, Stuart M Flechner, Aaron B Kantor, Christopher Marsh, Daniel R Salomon
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13358 (2010)
A major challenge for the field of transplantation is the lack of understanding of genomic and molecular drivers of early post-transplant immunity. The early immune response creates a complex milieu that determines the course of ensuing immune events
Externí odkaz:
https://doaj.org/article/2fea5ea758d448d288171a6b5a16dfe2
Autor:
Yevgeniy A Grigoryev, Sunil M Kurian, Aleksey A Nakorchevskiy, John P Burke, Daniel Campbell, Steve R Head, Jun Deng, Aaron B Kantor, John R Yates, Daniel R Salomon
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7906 (2009)
Alternative splicing of pre-mRNA is a mechanism that increases the protein diversity of a single gene by differential exon inclusion/exclusion during post-transcriptional processing. While alternative splicing is established to occur during lymphocyt
Externí odkaz:
https://doaj.org/article/a82f3247d986476b9fb3f6969cabfa2a
Autor:
Sunil M Kurian, Raymond Heilman, Tony S Mondala, Aleksey Nakorchevsky, Johannes A Hewel, Daniel Campbell, Elizabeth H Robison, Lin Wang, Wen Lin, Lillian Gaber, Kim Solez, Hamid Shidban, Robert Mendez, Randolph L Schaffer, Jonathan S Fisher, Stuart M Flechner, Steve R Head, Steve Horvath, John R Yates, Christopher L Marsh, Daniel R Salomon
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6212 (2009)
Despite significant improvements in life expectancy of kidney transplant patients due to advances in surgery and immunosuppression, Chronic Allograft Nephropathy (CAN) remains a daunting problem. A complex network of cellular mechanisms in both graft
Externí odkaz:
https://doaj.org/article/0c9f33ec60164b06bc9ee9841e64192e
Autor:
Mamatha Bhat, Elisa Pasini, Preya Patel, Jeffrey Yu, Cristina Baciu, Sunil M. Kurian, Josh Levitsky
Publikováno v:
Cancer Medicine, Vol 12, Iss 4, Pp 5150-5157 (2023)
Abstract Long‐term survival of transplant recipients is significantly impacted by malignancy. We aimed to determine whether calcineurin inhibitor (CNI)‐treated recipients converted to and weaned off molecular target of rapamycin inhibitor (mTOR
Externí odkaz:
https://doaj.org/article/a39e529b5db04c17b7d40c49e250da16
Autor:
Sunil M. Kurian, PhD, Darren E. Stewart, MS, Alice Toll, MS, Kyle Checchi, MD, Jamie Case, PhD, Christopher L. Marsh, MD
Publikováno v:
Transplantation Direct, Vol 8, Iss 12, p e1414 (2022)
Background. Delayed graft function (DGF) after kidney transplantation is associated with higher rates of acute rejection and poor graft survival and outcomes. Current DGF definitions based on posttransplant need for dialysis are not standardized and
Externí odkaz:
https://doaj.org/article/fa682e178e704f30bc03ea101e8b9c00
Autor:
Sean E. DeWolf, Sashi G. Kasimsetty, Alana A. Hawkes, Lisa M. Stocks, Sunil M. Kurian, Dianne B. McKay
Publikováno v:
Transplantation. 106(8)
Renal ischemia-reperfusion injury (IRI) predictably causes acute kidney injury after shock and major cardiovascular procedures in all kidneys procured for transplantation. The earliest events of IRI are triggered by molecules released from injured ce
Autor:
Christopher L. Marsh, John Holman, Michael Abecassis, Steve Kleiboeker, Sunil M. Kurian, Christabel Rebello, Susan S Brietigam, Lihui Zhao, Sookhyeon Park, David J. Taber, Emilio D. Poggio, John J. Friedewald, Kexin Guo, Juston C Weems, Raymond L. Heilman, Rohita Sinha
Publikováno v:
Clinical Journal of the American Society of Nephrology. 16:1539-1551
Background and objectives Subclinical acute rejection is associated with poor outcomes in kidney transplant recipients. As an alternative to surveillance biopsies, noninvasive screening has been established with a blood gene expression profile. Donor
Autor:
Sunil M. Kurian, Paul R Lewis, Jamie Case, Christopher L. Marsh, Randolph Schaffer, Steven Steuterman, Mary A. Decoteau, Jonathan S. Fisher
Publikováno v:
Journal of Radiological Protection. 41:N1-N11
Yttrium-90 (Y-90) radioembolization for the treatment of hepatocellular carcinoma can present safety challenges when transplanting recently treated Y-90 patients. To reduce surgeons' contact with radioactive tissue and remain within occupational dose