Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Sunil K Shaw"'
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26581 (2011)
Sustained β-adrenergic receptors (βAR) activation leads to cardiac hypertrophy and prevents left ventricular (LV) atrophy during LV unloading. The immediate signaling pathways downstream from βAR stimulation, however, have not been well investigat
Externí odkaz:
https://doaj.org/article/baf59d98df444db68c04b49379b3c378
Publikováno v:
J Vis Exp
C. parapsilosis (Cp) is an emerging cause of bloodstream infections in certain populations. The Candida clade, including Cp, is increasingly developing resistance to the first and the second line of antifungals. Cp is frequently isolated from hands a
Autor:
Matthew N. Neale, Sunil K. Shaw, Alper Uzun, Abigail Cuevas, Joseph M. Bliss, Sarah J. Longley, George A. Tollefson
Publikováno v:
mSphere
mSphere, Vol 6, Iss 1 (2021)
mSphere, Vol 6, Iss 1 (2021)
Candida parapsilosis has emerged as a frequent cause of invasive candidiasis with increasing evidence of unique biological features relative to C. albicans. As it adapts to conditions within a mammalian host, rapid changes in gene expression are nece
Autor:
Yi-Tang Tseng, Chanika Phornphutkul, Yanchun Xu, Sunil K. Shaw, D. Grahame Hardie, Alexander Gray, James F. Padbury, Alper Uzun
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 313:H283-H292
PRKAG2 encodes the γ2-subunit isoform of 5′-AMP-activated protein kinase (AMPK), a heterotrimeric enzyme with major roles in the regulation of energy metabolism in response to cellular stress. Mutations in PRKAG2 have been implicated in a unique h
Autor:
Quanfu Mao, Claire Anne Therese M Hemedez, Sunil K. Shaw, Elizabeth Trail-Burns, Joseph M. Bliss, Sharon Chu, Monique E. De Paepe
Publikováno v:
Pediatr Dev Pathol
Introduction/ObjectivesNon- albicans Candida species such as Candida parapsilosis and Candida glabrata have emerged as prevalent pathogens in premature infants. The aim of this study was to systematically delineate the histopathologic findings in neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b882b2567953fa94528bafba831000c
https://europepmc.org/articles/PMC9620501/
https://europepmc.org/articles/PMC9620501/
Autor:
Sonia S. Laforce-Nesbitt, Kyle A. Glass, Sunil K. Shaw, Denny J. Kim, Sarah J. Longley, Matthew N. Neale, Joseph M. Bliss, Jeremy D. Wortzel
Publikováno v:
Infection and immunity. 86(4)
The yeast Candida parapsilosis is an increasingly common cause of systemic fungal infections among immunocompromised individuals, including premature infants. Adhesion to host surfaces is an important step in pathogenesis, but this process has not be
Autor:
Nicholi Vorsa, Preetpal S. Sidhu, Thilo S. Lange, Laurent Brard, N. Kawar, Russell Hopson, Timothy C. Horan, Shannon MacLaughlan, James F. Padbury, Richard G. Moore, Alper Uzun, Rakesh K. Singh, Ajay P. Singh, Kyle A. Glass, Sunil K. Shaw, Leggy A. Arnold, Kyu K. Kim
Publikováno v:
Genes & Cancer. 4:524-534
Hypercalcemia remains a major impediment to the clinical use of vitamin D in cancer treatment. Approaches to remove hypercalcemia and development of nonhypercalcemic agents can lead to the development of vitamin D-based therapies for treatment of var
Publikováno v:
Biochemical and Biophysical Research Communications. 400:661-666
The mammalian genome encodes multiple WASP1 (Wiskott-Aldrich Syndrome Protein)/WAVE (WASP-family Verprolin homologous) proteins. Members of this family interact with the Arp (actin related protein) 2/3 complex to promote growth of a branched actin ne
Publikováno v:
Gynecologic Oncology. 109:240-249
Objective A novel indole ethyl isothiocyanate derivative (7Me-IEITC) was defined as a potent growth-suppressing agent to cell lines derived from ovarian cancers. Key mechanisms of the cellular response in vitro were studied and suggest a potential of
Autor:
Juan Sanchez-Esteban, Hyeon-Soo Lee, Yulian Wang, Benjamin S. Maciejewski, Ophira Silbert, Sunil K. Shaw
Publikováno v:
Experimental Lung Research. 34:663-680
Mechanical forces are critical for normal fetal lung development. However, the signaling events that promote lung maturation are not fully understood. In this study, the authors analyzed the role of Rho family guanidine triphosphatases (GTPases) in i