Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Sunil J. Advani"'
Autor:
Dina V. Hingorani, Michael M. Allevato, Maria F. Camargo, Jacqueline Lesperance, Maryam A. Quraishi, Joseph Aguilera, Ida Franiak-Pietryga, Daniel J. Scanderbeg, Zhiyong Wang, Alfredo A. Molinolo, Diego Alvarado, Andrew B. Sharabi, Jack D. Bui, Ezra E. W. Cohen, Stephen R. Adams, J. Silvio Gutkind, Sunil J. Advani
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Monomethyl auristatin (MMAE), also known for its radiosensitizer properties, is a common antibody drug conjugate used for cancer therapy. Here the authors show that, in combination with radiotherapy, tumor-directed antibodies or peptides conjugated t
Externí odkaz:
https://doaj.org/article/72a567e57f8f44099d033840d2c36067
Publikováno v:
Pharmaceutics, Vol 13, Iss 3, p 365 (2021)
Recent advances in immunotherapy have revolutionized cancer therapy. Immunotherapies can engage the adaptive and innate arms of the immune system. Therapeutics targeting immune checkpoint inhibitors (i.e., CTLA-4; PD-1, and PD-L1) have shown efficacy
Externí odkaz:
https://doaj.org/article/e0910e6f97284d0b8db6239b45e3a1b6
Autor:
RaeAnna Wilson, Cristina Espinosa-Diez, Nathan Kanner, Namita Chatterjee, Rebecca Ruhl, Christina Hipfinger, Sunil J. Advani, Jie Li, Omar F. Khan, Aleksandra Franovic, Sara M. Weis, Sushil Kumar, Lisa M. Coussens, Daniel G. Anderson, Clark C. Chen, David A. Cheresh, Sudarshan Anand
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
The tumour microenvironment can be modulated to sensitize tumours to the effects of therapy. Here the authors show that radiation induced miR-103 downregulates TREX1 in endothelial cells, decreases angiogenesis and leads to the secretion of proinflam
Externí odkaz:
https://doaj.org/article/a01c9f15bea14236bb83264f01ebc409
Autor:
Stephen R. Adams, Howard C. Yang, Elamprakash N. Savariar, Joe Aguilera, Jessica L. Crisp, Karra A. Jones, Michael A. Whitney, Scott M. Lippman, Ezra E. W. Cohen, Roger Y. Tsien, Sunil J. Advani
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Drugs that sensitize tumour cells to ionizing radiation are prized because they can overcome resistance to radiotherapy. Here, the authors show that anti-tubulin drugs conjugated to cetuximab or trastuzumab can radiosensitize EGFR- or HER2-expressing
Externí odkaz:
https://doaj.org/article/68ca94c8c46f45f584cf14bf29ee56ae
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
Antibody conjugation to drug and Cy5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a179658065a55345f7cf28265177a8b
https://doi.org/10.1158/1535-7163.22510627.v1
https://doi.org/10.1158/1535-7163.22510627.v1
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
MMAF anti-HER2 antibody conjugates spatial localization in HER2 negative tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae83cc61940585a81d6fb8e38d575c3
https://doi.org/10.1158/1535-7163.22510618
https://doi.org/10.1158/1535-7163.22510618
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
Effect of auristatin antibody drug conjugates in combination with IR on mouse body weight.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bb299fd6b025e9e09dc22f7a1e311e
https://doi.org/10.1158/1535-7163.22510609
https://doi.org/10.1158/1535-7163.22510609
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
Statistical analysis of xenograft studies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a1fd44762e98c536c352fc441be0ea
https://doi.org/10.1158/1535-7163.22510606
https://doi.org/10.1158/1535-7163.22510606
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
The most successful therapeutic strategies for locally advanced cancers continue to combine decades-old classical radiosensitizing chemotherapies with radiotherapy. Molecular targeted radiosensitizers offer the potential to improve the therapeutic ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd3f628464365f0f590a2f3623f5545
https://doi.org/10.1158/1535-7163.c.6539665.v1
https://doi.org/10.1158/1535-7163.c.6539665.v1
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
Pertuzumab conjugated MMAE and IR tumor control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad88318303c9787d3c2aff057aa22641
https://doi.org/10.1158/1535-7163.22510612.v1
https://doi.org/10.1158/1535-7163.22510612.v1