Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sunil Bhurtel"'
Autor:
Ji Geng, Shuangxi Li, Yu Li, Zhihao Wu, Sunil Bhurtel, Suman Rimal, Danish Khan, Rani Ohja, Onn Brandman, Bingwei Lu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Translational control exerts immediate effect on the composition, abundance, and integrity of the proteome. Ribosome-associated quality control (RQC) handles ribosomes stalled at the elongation and termination steps of translation, with ZNF5
Externí odkaz:
https://doaj.org/article/992df18d0d6e406991eea85200ad04af
Reverse electron transfer is activated during aging and contributes to aging and age‐related disease
Autor:
Suman Rimal, Ishaq Tantray, Yu Li, Tejinder Pal Khaket, Yanping Li, Sunil Bhurtel, Wen Li, Cici Zeng, Bingwei Lu
Publikováno v:
EMBO reports. 24
Autor:
Nikita Katila, Ramesh Duwa, Sunil Bhurtel, Shristi Khanal, Srijan Maharjan, Jee-Heon Jeong, Sooyeun Lee, Dong-Young Choi, Simmyung Yook
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 346
Parkinson's disease (PD) is a debilitating neurodegenerative condition characterized by the loss of dopaminergic neurons within the substantia nigra. The specific molecular mechanisms through which PD-associated neuronal loss occurs remain unclear, a
Publikováno v:
Biochemical pharmacology. 192
The neuropathological hallmark of Parkinson's disease (PD) is the preferential loss of dopaminergic neurons in the substantia nigra and presence of Lewy bodies in the dying neurons. Though specific molecular mechanisms for the neurodegeneration remai
Autor:
Gulam Muhammad Khan, Raj Kumar Thapa, Amrita Khakurel, Gita Shrestha, Nikita Katila, Sunil Bhurtel
Publikováno v:
Journal of Health and Allied Sciences. 3:64-67
Hypertension is a chronic medical condition which remains inadequately managed everywhere. Medication adherence (MA) is a critical parameter for achieving strict blood pressure (BP) control in patients undergoing antihypertensive therapy (AHT). Good
Autor:
Jin Tae Hong, Hyukjae Choi, Nikita Katila, Sunil Bhurtel, Sunil Srivastav, Dong-Young Choi, Sailesh Maharjan, Sabita Neupane
Publikováno v:
The Journal of Nutritional Biochemistry. 69:73-86
Microbiota in the gut affect brain physiology via various pathways, and dysbiosis seems to play a role in the pathogenesis of Parkinson's disease (PD). Probiotics showed pleiotropic effects on functions of the central nervous system via microbiota-gu
Autor:
Nikita Katila, Sunil Bhurtel, Dong-Young Choi, Sabita Neupane, Pil-Hoon Park, Sunil Srivastav, Sina Shadfar, Jin Tae Hong
Publikováno v:
Journal of Chemical Neuroanatomy. 94:173-182
IL-32 is a proinflammatory cytokine, and involved in various diseases including infection, inflammation, and cancer. However, effects of IL-32 on neuroinflammation remain obscure. Herein, we examined the effects of IL-32β on systemic LPS-induced neu
Publikováno v:
Neurochemistry International. 148:105120
Oxidative stress and mitochondrial dysfunction are now widely accepted as the major factors involved in the pathogenesis of Parkinson's disease (PD). Rotenone, a commonly used environmental toxin also reproduces these principle pathological features
Autor:
Dong-Young Choi, Uttam Ojha, Sina Shadfar, Jin Tae Hong, Sunil Bhurtel, Do Young Yoon, Sunil Srivastav, Pil-Hoon Park, Yu Yeon Jung, Nikita Katila, Dong Ju Son, Sabita Neupane
Publikováno v:
Neurochemistry International. 102:79-88
Parkinson's disease (PD) is a neurodegenerative disorder characterized by prominent loss of the nigral dopaminergic neurons and motor symptoms, such as resting tremor and bradykinesia. Evidence suggests that neuroinflammation may play a critical role
Autor:
Sunil Bhurtel, Sina Shadfar, Yu-Gyeong Kim, Nikita Katila, Sunil Srivastav, Jin Tae Hong, Uttam Ojha, Gil-Saeng Jeong, Pil-Hoon Park, Sabita Neupane, Dong-Young Choi
Publikováno v:
Molecular Neurobiology. 55:554-566
Neurotrophic factors are essential for neuronal survival, plasticity, and development and have been implicated in the action mechanism of antidepressants. In this study, we assessed the neurotrophic factor-inducing and neuroprotective properties of a