Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sunil A. Agnihotri"'
Autor:
Amit K. Shah, Sunil A. Agnihotri
Publikováno v:
Journal of Controlled Release. 156:281-296
Preclinical profiling for a New Chemical Entity (NCE), if carried out carefully, can be a good predictor of human clinical outcome. Along with the pre-clinical study design a thorough understanding of the physico-chemical properties of the drug candi
Autor:
Vishwanath Venketaraman, Guru V. Betageri, Carlos Guerra, Jeffrey Wang, Krishna Muppidi, Andrew S. Pumerantz, Sunil A. Agnihotri
Publikováno v:
International Journal of Antimicrobial Agents. 37:140-144
Meticillin-resistant Staphylococcus aureus (MRSA) can persist in alveolar macrophages and contribute to clinical failure of intravenous vancomycin to cure pneumonia. In this study, it was shown that vancomycin in standard solution is unable to kill i
Autor:
Samia Daoud-Mahammed, Kawthar Bouchemal, Ruxandra Gref, Stefanie Kloters, Patrick Couvreur, Sunil A. Agnihotri
Publikováno v:
Current Nanoscience. 6:654-665
Publikováno v:
Drug Development and Industrial Pharmacy. 33:1254-1262
Timolol maleate-loaded chitosan (CS) nanoparticles were prepared by desolvation method. Experimental variables such as molecular weight of CS and amount of crosslinking agent were varied to study their effect on drug entrapment efficiency, size and r
Publikováno v:
International Journal of Pharmaceutics. 324:103-115
This paper describes the synthesis of capecitabine-loaded semi-interpenetrating network hydrogel microspheres of chitosan-poly(ethylene oxide-g-acrylamide) by emulsion crosslinking using glutaraldehyde. Poly(ethylene oxide) was grafted with polyacryl
Autor:
Sangamesh A. Patil, Sunil A. Agnihotri, Ajit P. Rokhade, N. N. Mallikarjuna, Padmakar V Kulkarni, Tejraj M. Aminabhavi
Publikováno v:
Carbohydrate Polymers. 65:243-252
Semi-interpenetrating polymer network (IPN) microspheres of natural polymers, viz., gelatin and sodium carboxymethyl cellulose (NaCMC) were prepared by using glutaraldehyde (GA) as a crosslinker. Ketorolac tromethamine (KT), an anti-inflammatory and
Publikováno v:
Journal of Applied Polymer Science. 102:3255-3258
Chitosan and chitosan-grafted-acrylamide were subjected to degradation in the presence and absence of a degrading agent at 37°C by measuring the viscosity of polymer solutions. Extracts from the fresh rat droppings were used as the degrading agent t
Graft copolymerization of methacrylic acid onto guar gum, using potassium persulfate as an initiator
Publikováno v:
Journal of Applied Polymer Science. 101:618-623
Graft copolymerization of methacrylic acid (MAA) onto guar gum (GG) was carried out by free radical initiation mechanism by using potassium persulfate (PPS) as an initiator. It was found that % grafting, grafting efficiency, and % conversion were all
Autor:
Tejraj M. Aminabhavi, Sunil A. Agnihotri, Kumaresh S. Soppimath, N. N. Mallikarjuna, Padmakar V. Kulkarni
Publikováno v:
Journal of Applied Polymer Science. 100:486-494
A gastro retentive drug-delivery system for nifedipine was developed by incorporating the drug in cellulose acetate hollow microspheres capable of floating on the gastric and intestinal fluid. The microspheres were prepared by solvent diffusion–eva
Autor:
Sunil A. Agnihotri, Raghavendra V. Kulkarni, Padmakar V Kulkarni, N. N. Mallikarjuna, Tejraj M. Aminabhavi
Publikováno v:
Journal of Applied Polymer Science. 96:301-311
The electrically modulated transdermal migration of diclofenac sodium (DS), diclofenac potassium (DP), and diclofenac diethylammonium (DD) drugs from the hydrogels of sodium alginate (NaAlg), carbopol (CP), and blends of NaAlg with CP prepared in 2:1