Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Sunil, Nagpal"'
Autor:
Sunil Nagpal, Sarvesh Kumar Srivastava
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Ingestible microdevices represent a breakthrough in non-invasive sampling of the human gastrointestinal (GI) tract. By capturing the native spatiotemporal microbiome and intricate biochemical gradients, these devices allow a non-invasive mul
Externí odkaz:
https://doaj.org/article/3dd8a51bc93949aa9997be4f1d81a9cb
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Bacterial communities are often concomitantly present with numerous microorganisms in the human body and other natural environments. Amplicon-based microbiome studies have generally paid skewed attention, that too at a rather shallow genus l
Externí odkaz:
https://doaj.org/article/bc3d5ddda4d949679b2d7507c05f1c9c
Autor:
Sunil Nagpal, Sharmila S. Mande
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Tumor microenvironment has recently been ascribed a new hallmark—the polymorphic microbiome. Accumulating evidence regarding the tissue specific territories of tumor-microbiome have opened new and interesting avenues. A pertinent question
Externí odkaz:
https://doaj.org/article/dca98e2412074d2f9b0e066a538bf8fd
Autor:
Katie Lowe, Annabelle Small, Qingxuan Song, Ling-Yang Hao, William Murray-Brown, Susanna Proudman, Malcolm D. Smith, Sunil Nagpal, Mihir D. Wechalekar
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Programmed cell death protein 1 (PD-1)-expressing T cells are expanded in individuals with established rheumatoid arthritis (RA). However, little is known about their functional role in the pathogenesis of early RA. To address this, we inves
Externí odkaz:
https://doaj.org/article/c8beaac6c2f84d4dbdb177179193cb1d
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Natural language processing (NLP) algorithms process linguistic data in order to discover the associated word semantics and develop models that can describe or even predict the latent meanings of the data. The applications of NLP become mult
Externí odkaz:
https://doaj.org/article/f591dd1577af468e982ec4a70d1c53a1
Autor:
Susanna M Proudman, Ling-Yang Hao, William Murray-Brown, Helen Weedon, Malcolm D Smith, Mihir D Wechalekar, Susan E Lester, Sunil Nagpal, Yanxia Guo, Annabelle Small, Katie Lowe, Navin L Rao
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Objectives Programmed cell death protein 1 (PD-1)-expressing T cells are implicated in the pathogenesis of autoimmune inflammatory diseases such as rheumatoid arthritis. A subset of CXCR5− T cells, termed T peripheral helper (Tph) cells, which driv
Externí odkaz:
https://doaj.org/article/f7fc10303c3b466ab3977cd24072ecdf
Autor:
Nitin Bayal, Sunil Nagpal, Mohammed Monzoorul Haque, Milind S. Patole, Yogesh Shouche, Shekhar C. Mande, Sharmila S. Mande
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Although skin is the primary affected organ in Leprosy, the role of the skin microbiome in its pathogenesis is not well understood. Recent reports have shown that skin of leprosy patients (LP) harbours perturbed microbiota which grants infla
Externí odkaz:
https://doaj.org/article/0210b6b4b58d4191b4181edecd189966
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Most biological experiments are inherently designed to compare changes or transitions of state between conditions of interest. The advancements in data intensive research have in particular elevated the need for resources and tool
Externí odkaz:
https://doaj.org/article/2c1c323443734e5191c2e28dce26236f
Autor:
Mary Canavan, Viviana Marzaioli, Vipul Bhargava, Sunil Nagpal, Phil Gallagher, Conor Hurson, Ronan Mullan, Douglas J. Veale, Ursula Fearon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
ObjectiveTo examine the role of synovial CD1c+DCs in patients with Inflammatory Arthritis (IA) with a specific focus on the transcriptional and maturation signatures that govern their function.MethodsRNA sequencing was performed on healthy control (H
Externí odkaz:
https://doaj.org/article/71c0a64c744d457b9582855f3937bb8d
Autor:
Achilleas Floudas, Nuno Neto, Viviana Marzaioli, Kieran Murray, Barry Moran, Michael G. Monaghan, Candice Low, Ronan H. Mullan, Navin Rao, Vinod Krishna, Sunil Nagpal, Douglas J. Veale, Ursula Fearon
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
While autoantibodies are used in the diagnosis of rheumatoid arthritis (RA), the function of B cells in the inflamed joint remains elusive. Extensive flow cytometric characterization and SPICE algorithm analyses of single-cell synovial tissue from pa
Externí odkaz:
https://doaj.org/article/84eac101717343a58bf6b2f685169e06