Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Sunia A Trauger"'
Autor:
Aurora Alvarez-Buylla, Cheyenne Y Payne, Charles Vidoudez, Sunia A Trauger, Lauren A O'Connell
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0264540 (2022)
Poison frogs bioaccumulate alkaloids for chemical defense from their arthropod diet. Although many alkaloids are accumulated without modification, some poison frog species can metabolize pumiliotoxin (PTX 251D) into the more potent allopumiliotoxin (
Externí odkaz:
https://doaj.org/article/08a964d5666445bf915356dc16216438
Autor:
Nora A Moskowitz, Alexandre B Roland, Eva K Fischer, Ndimbintsoa Ranaivorazo, Charles Vidoudez, Marianne T Aguilar, Sophia M Caldera, Jacqueline Chea, Miruna G Cristus, Jett P Crowdis, Bluyé DeMessie, Caroline R desJardins-Park, Audrey H Effenberger, Felipe Flores, Michael Giles, Emma Y He, Nike S Izmaylov, ChangWon C Lee, Nicholas A Pagel, Krystal K Phu, Leah U Rosen, Danielle A Seda, Yong Shen, Santiago Vargas, Andrew W Murray, Eden Abebe, Sunia A Trauger, David A Donoso, Miguel Vences, Lauren A O'Connell
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0207940 (2018)
Poison frogs acquire chemical defenses from the environment for protection against potential predators. These defensive chemicals are lipophilic alkaloids that are sequestered by poison frogs from dietary arthropods and stored in skin glands. Despite
Externí odkaz:
https://doaj.org/article/46b30a198fb3489293183c6da339fab1
Autor:
Sanchari Bhattacharyya, Shimon Bershtein, Jin Yan, Tijda Argun, Amy I Gilson, Sunia A Trauger, Eugene I Shakhnovich
Publikováno v:
eLife, Vol 5 (2016)
Gene dosage toxicity (GDT) is an important factor that determines optimal levels of protein abundances, yet its molecular underpinnings remain unknown. Here, we demonstrate that overexpression of DHFR in E. coli causes a toxic metabolic imbalance tri
Externí odkaz:
https://doaj.org/article/3c5237d307ba4c0cb4d775dbc0e60882
Publikováno v:
eLife, Vol 5 (2016)
Phenotypic screens allow the identification of small molecules with promising anticancer activity, but the difficulty in characterizing the mechanism of action of these compounds in human cells often undermines their value as drug leads. Here, we use
Externí odkaz:
https://doaj.org/article/8362c83a8c974bbda3539dc7cbe4be25
Autor:
Kristopher J Koudelka, Giuseppe Destito, Emily M Plummer, Sunia A Trauger, Gary Siuzdak, Marianne Manchester
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000417 (2009)
Cowpea mosaic virus (CPMV) is a plant comovirus in the picornavirus superfamily, and is used for a wide variety of biomedical and material science applications. Although its replication is restricted to plants, CPMV binds to and enters mammalian cell
Externí odkaz:
https://doaj.org/article/18fba69130b0475ab1059b7011dfbee0
Autor:
Tejia Zhang, Ivy Alonzo, Chris Stubben, Yijie Geng, Chelsea Herdman, Nancy Chandler, Kim P. Doane, Brock R. Pluimer, Sunia A. Trauger, Randall T. Peterson
Publikováno v:
Disease Models & Mechanisms.
Sphingolipidoses are a subcategory of lysosomal storage diseases (LSDs) caused by mutations in enzymes of the sphingolipid catabolic pathway. Like many LSDs, neurological involvement in sphingolipidoses leads to early mortality with limited treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53d1b134bc38db0ef41254fecca2afa6
https://doi.org/10.1242/dmm.049995
https://doi.org/10.1242/dmm.049995
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09601bf6592d0cd2ee5b5d67de96f13d
https://doi.org/10.1096/fasebj.2022.36.s1.l7930
https://doi.org/10.1096/fasebj.2022.36.s1.l7930
Autor:
Cambridge Rindge, Charles Vidoudez, Eva K. Fischer, Olivia C. Nieves, Luis A. Coloma, Tammy Fay, Masconomet Biotechnology Class, Nora A. Moskowitz, Latin Biology Class, David A. Donoso, Sunia A. Trauger, Lauren A. O’Connell, Barbara Dorritie
Publikováno v:
Neotropical Biodiversity, Vol 6, Iss 1, Pp 75-87 (2020)
Much of the world’s biodiversity is held within tropical rainforests, which are increasingly fragmented by agricultural practices. In these threatened landscapes, there are many organisms that acquire chemical defenses from their diet and are there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea1ed0387d471e3f2e9b01fe6851bc1c
https://doi.org/10.1080/23766808.2020.1744957
https://doi.org/10.1080/23766808.2020.1744957
Autor:
Eugene Serebryany, Victor Y. Zhao, Kibum Park, Amir Bitran, Sunia A. Trauger, Bogdan Budnik, Eugene I. Shakhnovich
SummaryNon-native conformations drive protein misfolding diseases, complicate bioengineering efforts, and fuel molecular evolution. No current experimental technique is well-suited for elucidating them and their phenotypic effects. Especially intract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c85c77cc855eab75627517cf394198
Autor:
Aurora Alvarez-Buylla, Lauren A. O’Connell, Charles Vidoudez, Sunia A. Trauger, Cheyenne Payne
Publikováno v:
PloS one. 17(3)
Poison frogs bioaccumulate alkaloids for chemical defense from their arthropod diet. Although many alkaloids are accumulated without modification, some poison frog species can metabolize pumiliotoxin (PTX 251D) into the more potent allopumiliotoxin (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0bb8fec10c42b3277659292ff4f5fd
https://pubmed.ncbi.nlm.nih.gov/35275922
https://pubmed.ncbi.nlm.nih.gov/35275922