Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Suni G. Allen"'
Publikováno v:
American Journal of Physiology-Renal Physiology. 295:F1601-F1612
The epithelial tight junction (TJ) was first described ultrastructurally as a fusion of the outer lipid leaflets of the adjoining cell membrane bilayers (hemifusion). The discovery of an increasing number of integral TJ and TJ-associated proteins has
Publikováno v:
Neuroscience. 141:77-86
When excitotoxic mechanisms are blocked, severe or prolonged hypoxia and hypoxia-ischemia can still kill neurons, by a mechanism which is poorly understood. We studied this "non-excitotoxic hypoxic death" in primary cultures of rat dentate gyrus neur
Publikováno v:
American Journal of Physiology-Renal Physiology. 287:F481-F491
The tight junction has been characterized as a domain of focal fusions of the exoplasmic leaflets of the lipid bilayers from adjacent epithelial cells. Approximating membranes to within fusion distance is a thermodynamically unfavorable process and r
Publikováno v:
Digestive Diseases and Sciences. 45:1472-1479
The in vivo immunological events in dextran sulfate sodium (DSS) -induced colitis were evaluated. Rats were fed water (control) or 5% DSS. Colonic sections were assessed by light microscopy, Gram stain, immunohistochemistry, and electron microscopy.
Publikováno v:
Journal of Investigative Dermatology. 98:73-78
The distribution of various glycoprotein molecules on the surface of follicular keratinocytes was studied with a panel of lectins with specificity for various sugar moieties on biopsy specimens from both bald/balding scalp and normal occipital scalp,
Publikováno v:
Neurobiology of Disease, Vol 37, Iss 2, Pp 394-402 (2010)
The mechanism of status epilepticus-induced neuronal death in the immature brain is not fully understood. In the present study, we examined the contribution of caspases in our lithium–pilocarpine model of status epilepticus in 14 days old rat pups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68731fc45f2b15a447421879556e7547
https://europepmc.org/articles/PMC2818381/
https://europepmc.org/articles/PMC2818381/
Mild as well as severe insults produce necrotic, not apoptotic, cells: evidence from 60-min seizures
Publikováno v:
Neuroscience letters. 469(3)
We tested the hypothesis that mild insults produce apoptotic, and severe insults necrotic, cells by subjecting adult Wistar rats to 60-min instead of 3-h generalized seizures. Rats’ brains were evaluated 6 and 24 h later for evidence of neuronal ne
Publikováno v:
Journal of neuroscience research. 87(9)
It is traditionally thought that excitotoxic necrosis is a passive mechanism that does not require the activation of a cell death program. In this study, we examined the contribution of the cytochrome c-dependent mitochondrial death pathway to excito
Publikováno v:
Australasian Journal of Dermatology. 32:151-157
SUMMARY Skin lesions associated with alpha1-antitrypsin deficiency are becoming better defined and understood. Deficiency in this major antiproteinase, which neutralizes multiple proteolytic enzymes ranging from collagenases and elastases to trypsin
Autor:
Madalene C.Y. Heng, Suni G. Allen
Publikováno v:
Journal of the American Academy of Dermatology. 25:778-786
In this article we describe the immunocytochemical and electron microscopic findings in five patients with toxic epidermal necrolysis. They indicate the occurrence of necrotic keratinocytes with nuclear disintegration associated with apposed dendriti