Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Sungyoul, Hong"'
Autor:
Jaebeom Cho, Hye-Young Min, Ho Jin Lee, Seung Yeob Hyun, Jeong Yeon Sim, Myungkyung Noh, Su Jung Hwang, Shin-Hyung Park, Hye-Jin Boo, Hyo-Jong Lee, Sungyoul Hong, Rang-Woon Park, Young Kee Shin, Mien-Chie Hung, Ho-Young Lee
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/b6b023cda3b74a22bcca808bf29b5323
Autor:
Chan Gyu Lee, TaeEun Kim, Sungyoul Hong, Jongwan Chu, Ju Eun Kang, Hee Geon Park, Jun Young Choi, Kyoung Song, Sun Young Rha, Soohyeon Lee, Joon-Seok Choi, Sun Min Kim, Hae Min Jeong, Young Kee Shin
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Type I interferon (IFN) has been approved as an anticancer agent to treat some malignancies. However, IFNs have a short in vivo half-life, systemic toxicity, and poor biophysical properties, which prevent it from being widely used for cancer therapy.
Externí odkaz:
https://doaj.org/article/6c9e811c8b6e4038a696676a57153737
Autor:
Nirmal Rajasekaran, Hun Soon Jung, Soo Hyeon Bae, Chaithanya Chelakkot, Sungyoul Hong, Jong-Sun Choi, Dong-Seok Yim, Yu-Kyoung Oh, Yoon-La Choi, Young Kee Shin
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 10, Pp 735-749 (2017)
Toxicity and resistance remain major challenges for advanced or recurrent cervical cancer therapies, as treatment requires high doses of chemotherapeutic agents. Restoration of TP53 and hypophosphorylated-retinoblastoma (pRB) proteins by human papill
Externí odkaz:
https://doaj.org/article/c2fa6c0b77124668958555288e269051
Autor:
Saehyung Lee, Woo Sung Son, Ho Bin Yang, Nirmal Rajasekaran, Sung-Su Kim, Sungyoul Hong, Joon-Seok Choi, Jun Young Choi, Kyoung Song, Young Kee Shin
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2019)
The glycoengineering approach is used to improve biophysical properties of protein-based drugs, but its direct impact on binding affinity and kinetic properties for the glycoengineered protein and its binding partner interaction is unclear. Type I in
Externí odkaz:
https://doaj.org/article/84282aa384e34d00b618008b96b0d5fb
Autor:
Su Jung Hwang, Hye-Young Min, Rang Woon Park, Jaebeom Cho, Ho-Young Lee, Mien Chie Hung, Hyo Jong Lee, Ho Jin Lee, Jeong Yeon Sim, Myungkyung Noh, Shin-Hyung Park, Seung Yeob Hyun, Hye-Jin Boo, Sungyoul Hong, Young Kee Shin
Publikováno v:
J Clin Invest
Slow-cycling/dormant cancer cells (SCCs) have pivotal roles in driving cancer relapse and drug resistance. A mechanistic explanation for cancer cell dormancy and therapeutic strategies targeting SCCs are necessary to improve patient prognosis, but ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0309eae1d7b827dd71a38c35cea44eab
https://doi.org/10.1172/jci171901
https://doi.org/10.1172/jci171901
Autor:
Kwang-Soo Baek, Young-Su Yi, Young-Jin Son, Sulgi Yoo, Nak Yoon Sung, Yong Kim, Sungyoul Hong, Adithan Aravinthan, Jong-Hoon Kim, Jae Youl Cho
Publikováno v:
Journal of Ginseng Research, Vol 40, Iss 4, Pp 437-444 (2016)
Background: Although Korean Red Ginseng (KRG) has been traditionally used for a long time, its anti-inflammatory role and underlying molecular and cellular mechanisms have been poorly understood. In this study, the anti-inflammatory roles of KRG-deri
Externí odkaz:
https://doaj.org/article/6f1e76bbb04c4343a146df9989c2813e
Autor:
Nam Ah Kim, Sungyoul Hong, Ki Hyun Kim, Du Hyung Choi, Joo Seok Kim, Kyung Eui Park, Jun Young Choi, Young Kee Shin, Seong Hoon Jeong
Publikováno v:
Pharmaceutics, Vol 12, Iss 2, p 121 (2020)
c-Met is a receptor tyrosine kinase with no commercially available product despite being a pivotal target in cancer progression. Unlike other c-Met inhibitors that fail clinically, ABN401 is a newly synthesized c-Met inhibitor that is not potentially
Externí odkaz:
https://doaj.org/article/d47a1325e7ed40efa896452cd874650d
Autor:
Yanyan Yang, Jongsung Lee, Man Hee Rhee, Tao Yu, Kwang-Soo Baek, Nak Yoon Sung, Yong Kim, Keejung Yoon, Ji Hye Kim, Yi-Seong Kwak, Sungyoul Hong, Jong-Hoon Kim, Jae Youl Cho
Publikováno v:
Journal of Ginseng Research, Vol 39, Iss 1, Pp 61-68 (2015)
Background: Korean Red Ginseng (KRG) is a representative traditional herbal medicine with many different pharmacological properties including anticancer, anti-atherosclerosis, anti-diabetes, and anti-inflammatory activities. Only a few studies have e
Externí odkaz:
https://doaj.org/article/60777c7a91b54d43b817e092d8f057d5
Autor:
Hobin Yang, Hayeon Park, Yong Jin Lee, Jun Young Choi, TaeEun Kim, Nirmal Rajasekaran, Saehyung Lee, Kyoung Song, Sungyoul Hong, Joon-Seok Choi, Hyunbo Shim, Young-Deug Kim, Soohyun Hwang, Yoon-La Choi, Young Kee Shin
Publikováno v:
Biomolecules, Vol 10, Iss 1, p 51 (2019)
Most malignant tumors originate from epithelial tissues in which tight junctions mediate cell−cell interactions. Tight junction proteins, especially claudin-3 (CLDN3), are overexpressed in various cancers. Claudin-3 is exposed externally during tum
Externí odkaz:
https://doaj.org/article/4c94c1650f514e20bb65a9d3a56fb328
Autor:
Chan Gyu Lee, Minkyung Park, Hyun Kyung Lee, Na Young Kim, Jun Young Choi, Sungyoul Hong, Young Kee Shin, Hae Min Jeong
Publikováno v:
Cancer Research. 83:1803-1803
Background: Trastuzumab deruxtecan (T-DXd) has been approved in various types cancer and recently expanded its indication to cancers with various HER2 expressions, such as HER2-low breast cancer. Since the effect of T-DXd is based on toxin payload, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13e7f13a1905c8a88b474dfd15d2df49
https://doi.org/10.1158/1538-7445.am2023-1803
https://doi.org/10.1158/1538-7445.am2023-1803