Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Sungwoo, Jo"'
Autor:
So-Hyeon Park, Yunkyung Heo, Il Kwon, Sungwoo Jo, Hyejin Jeon, Yechan Lee, Jieun Kim, Ji Hoe Heo, Wan Namkung
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Protease-activated receptor 1 (PAR1) is expressed in human platelets and can be activated by low concentrations of thrombin. Vorapaxar, a selective antagonist of PAR1, inhibits thrombin-induced calcium mobilization in human platelet, whic
Externí odkaz:
https://doaj.org/article/67672e0af5c44d6fa1c35245e93b5e99
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Sugammadex reverses neuromuscular blockade by encapsulating steroidal neuromuscular blockers; therefore, it does not pharmacologically affect sedation levels. However, some clinicians avoid using it because of sudden unwanted acting out or p
Externí odkaz:
https://doaj.org/article/9f50a6a9362f4849b5f31172f7eaebbf
Autor:
Jinsei Jung, Shin Hye Noh, Sungwoo Jo, Doona Song, Min Jin Kang, Mi Hwa Shin, Hyun Jae Lee, Jae-Chul Pyun, Wan Namkung, Gyoonhee Han, Min Goo Lee, Jae Young Choi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115445- (2023)
Variants in SLC26A4 (pendrin) are the most common reasons for genetic hearing loss and vestibular dysfunction in East Asians. In patients with Pendred syndrome and DFNB4 (autosomal recessive type of genetic hearing loss 4), caused by variants in SLC2
Externí odkaz:
https://doaj.org/article/4959a1ba140a46e0a84a1435d1f205d7
Autor:
Sung Baek Jeong, Raju Das, Dong-Hyun Kim, Sion Lee, Hye In Oh, Sungwoo Jo, Yechan Lee, Jeongdong Kim, SeonJu Park, Dong Kyu Choi, Uk Yeol Moon, Oh-bin Kwon, Wan Namkung, Sungwoo Lee, Byoung Chul Cho, Joohan Woo, Yohan Seo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113373- (2022)
Anoctamin 1 (ANO1) is a calcium-activated chloride channel found in various cell types and is overexpressed in non-small cell lung cancer (NSCLC), a major cause of cancer-related mortality. With the rising interest in development of druggable compoun
Externí odkaz:
https://doaj.org/article/0d7d8a2863c942b9a4c38ca89e6a8cbc
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5168 (2022)
Volume-regulated anion channel (VRAC) is ubiquitously expressed and plays a pivotal role in vertebrate cell volume regulation. A heterologous complex of leucine-rich repeat containing 8A (LRRC8A) and LRRC8B-E constitutes the VRAC, which is involved i
Externí odkaz:
https://doaj.org/article/72e8d196559143d9a289d5276fa97472
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 12037 (2021)
Anoctamin1 (ANO1), a calcium-activated chloride channel, is frequently overexpressed in several cancers, including oral squamous cell carcinoma (OSCC). OSCC is a highly aggressive cancer and the most common oral malignancy. ANO1 has been proposed as
Externí odkaz:
https://doaj.org/article/3f56d5d5de6e42b3bc4e09e851a5a533
Publikováno v:
Energies, Vol 14, Iss 21, p 7206 (2021)
Because lithium-ion batteries are widely used for various purposes, it is important to estimate their state of health (SOH) to ensure their efficiency and safety. Despite the usefulness of model-based methods for SOH estimation, the difficulties of b
Externí odkaz:
https://doaj.org/article/85d0be4c45ce4c6ba53a4f5fc0b08fa5
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10847 (2021)
Calcium signaling plays a vital role in the regulation of various cellular processes, including activation, proliferation, and differentiation of T-lymphocytes, which is mediated by ORAI1 and potassium (K+) channels. These channels have also been ide
Externí odkaz:
https://doaj.org/article/6513992a01684abc89ce5122edf5c556
Autor:
Yohan Seo, Sung Baek Jeong, Joo Han Woo, Oh-Bin Kwon, Sion Lee, Hye In Oh, Sungwoo Jo, Seon Ju Park, Wan Namkung, Uk Yeol Moon, Sungwoo Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7100 (2021)
Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer-related mortality; thus, therapeutic targets continue to be developed. Anoctamin1 (ANO1), a novel drug target considered for the treatment of NSCLC, is a Ca2+-activated chlorid
Externí odkaz:
https://doaj.org/article/5ab6197f920e4700b1f2c35c6e81ca4b
Autor:
Yohan Seo, Nguyen Hoang Anh, Yunkyung Heo, So-Hyeon Park, Phan Van Kiem, Yechan Lee, Duong Thi Hai Yen, Sungwoo Jo, Dongkyu Jeon, Bui Huu Tai, Nguyen Hoai Nam, Chau Van Minh, Seung Hyun Kim, Nguyen Xuan Nhiem, Wan Namkung
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6470 (2020)
Anoctamin1 (ANO1), a calcium-activated chloride channel, is frequently overexpressed in several cancers, including human prostate cancer and oral squamous cell carcinomas. ANO1 plays a critical role in tumor growth and maintenance of these cancers. I
Externí odkaz:
https://doaj.org/article/f2e9b3dc15cc4b7e8380a2f2f017f401