Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sungshin Y. Choi"'
Autor:
Xiaoman Hong, Anamika Ratri, Sungshin Y. Choi, Joseph S. Tash, April E. Ronca, Joshua S. Alwood, Lane K. Christenson
Publikováno v:
npj Microgravity, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Ovarian steroids dramatically impact normal homeostatic and metabolic processes of most tissues within the body, including muscle, bone, neural, immune, cardiovascular, and reproductive systems. Determining the effects of spaceflight on the
Externí odkaz:
https://doaj.org/article/4fdd39a8dc864f128470ff20d63eda80
Autor:
Sung-Joon Lee, Sujata Kadambi, Kenneth C-W. Yu, Christopher David, Salman Azhar, Allen D. Cooper, Sungshin Y. Choi
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 1, Pp 27-35 (2005)
The LDL receptor and the LDL receptor-related protein (LRP) mediate the removal of chylomicron remnants. The LRP pathway involves sequestration of particles in the space of Disse. It has been proposed that either alone or in combination with other fa
Externí odkaz:
https://doaj.org/article/79ecc5a8309f4c51bc56472b92684940
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 12, Pp 2199-2210 (2004)
Apolipoprotein E2 (apoE2) and apoE3-Leiden cause chylomicron remnant accumulation (type III hyperlipidemia). However, the degree of dyslipidemia and its penetrance are different in humans and mice. Remnant uptake by isolated liver from apoE−/− mi
Externí odkaz:
https://doaj.org/article/51665064985b4d8f8185ad094f2a21f8
Autor:
Kenneth C-W. Yu, Christopher David, Sujata Kadambi, Andreas Stahl, Ken-Ichi Hirata, Tatsuro Ishida, Thomas Quertermous, Allen D. Cooper, Sungshin Y. Choi
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 9, Pp 1614-1623 (2004)
Both LPL and HL are synthesized in parenchymal cells, are secreted, and bind to endothelial cells. To learn where endothelial lipase (EL) is synthesized in adult animals, the localization of EL in mouse and rat liver was studied by immunohistochemica
Externí odkaz:
https://doaj.org/article/9cdf21377a3a4abca351ffbffee8eaa2
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 7, Pp 1266-1271 (2004)
HL is synthesized in hepatocytes and functions while bound to heparan sulfate proteoglycans (HSPGs) in sinusoidal endothelial cells. The HL-mediated uptake of lipoprotein requires cell-surface HSPG. The present study tested whether HL plays a role in
Externí odkaz:
https://doaj.org/article/77c8006e535447ae93a896dc2cbba8e2
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 11, Pp 1763-1769 (2002)
Endothelial lipase (EL) is a newly described member of the triglyceride lipase gene family. It has a considerable molecular homology with lipoprotein lipase (LPL) (44%) and hepatic lipase (HL) (41%). Unlike LPL and HL, this enzyme is synthesized by e
Externí odkaz:
https://doaj.org/article/1e837ec0273e44d8abb911fe0d470b73
Autor:
Sungshin Y. Choi, Samuel M. Cadena, Yasaman Shirazi-Fard, Stephanie Solis, Louis S. Stodieck, Ruth K. Globus, Amanda M. Saravia-Butler, Dennis Leveson-Gower, April E. Ronca, J. Beegle
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Animal models are useful for exploring the health consequences of prolonged spaceflight. Capabilities were developed to perform experiments in low earth orbit with on-board sample recovery, thereby avoiding complications caused by return to Earth. Fo
Autor:
Yasaman Shirazi-Fard, Cynthia-May S. Gong, Sungshin Y. Choi, David C. Scofield, David J. Olivos, Jonathan S. Harris, Paul Childress, Todd O. McKinley, Rasha Hammamieh, Alexander Brinker, Carolynn L. Conley, Tien-Min G. Chu, Melissa A. Kacena, Nabarun Chakraborty, Jeffrey D. Rytlewski
Publikováno v:
Life Sciences in Space Research. 16:52-62
Segmental bone defects (SBDs) secondary to trauma invariably result in a prolonged recovery with an extended period of limited weight bearing on the affected limb. Soldiers sustaining blast injuries and civilians sustaining high energy trauma typify
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 12, Pp 2199-2210 (2004)
Apolipoprotein E2 (apoE2) and apoE3-Leiden cause chylomicron remnant accumulation (type III hyperlip- idemia). However, the degree of dyslipidemia and its pene- trance are different in humans and mice. Remnant uptake by isolated liver from apoE � /
Very Low Density Lipoprotein (VLDL) Receptor-deficient Mice Have Reduced Lipoprotein Lipase Activity
Autor:
Hiroaki Yagyu, Yuko Kako, Ira J. Goldberg, Yunying Hu, Sungshin Y. Choi, E. Peer Lutz, André Bensadoun, Steven A. Marks
Publikováno v:
Journal of Biological Chemistry. 277:10037-10043
Although very low density lipoprotein (VLDL) receptor (VLDLr) knockout mice have been reported to have no lipoprotein abnormalities, they develop less adipose tissue than control mice when fed a high calorie diet. Mice that are deficient in adipose t