Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Sungpil Han"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 689 (2024)
Zolpidem is a widely prescribed hypnotic Z-drug used to treat short-term insomnia. However, a growing number of individuals intentionally overdose on these drugs. This study aimed to develop a predictive tool for physicians to assess patients with zo
Externí odkaz:
https://doaj.org/article/8ce2226814d243f596bef5c76b42b9e0
Autor:
Sungpil Han, Hee Youn Choi, Yo Han Kim, SeungChan Choi, Seokuee Kim, Ji Yeon Nam, Bongtae Kim, Geun Seog Song, Hyeong-Seok Lim, Kyun-Seop Bae
Publikováno v:
Gut and Liver, Vol 17, Iss 1, Pp 92-99 (2023)
Background/Aims: Tegoprazan, a novel potassium-competitive acid blocker, is expected to overcome the limitations of proton pump inhibitors and effectively control nocturnal acid breakthrough. To evaluate the pharmacodynamics of tegoprazan versus dexl
Externí odkaz:
https://doaj.org/article/031c5badeb3d4a6fa541965019b9a495
Autor:
Suji Kim, Suein Choi, Min Seo Lee, Mingyu Kim, Maria Park, Sungpil Han, Seunghoon Han, Hye Suk Lee, Sooyeun Lee
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Gamma-hydroxybutyric acid (GHB), used as a therapeutic and an illegal anesthetic, is a human neurotransmitter produced during gamma-aminobutyric acid (GABA) biosynthesis and metabolism. Potential biomarker metabolites of GHB intoxication have been id
Externí odkaz:
https://doaj.org/article/7b3c83fd0ad8462fbf7900a818817d35
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The Comprehensive in vitro Proarrhythmia Assay (CiPA) project suggested the torsade metric score (TMS) which requires substantial computing resources as a useful biomarker to predict proarrhythmic risk from human ether-à-go-go–related gene (hERG)
Externí odkaz:
https://doaj.org/article/576fa38fe6a0420b8072ddc77811208b
Autor:
Moon Hee Lee, Seok-Kyu Yoon, Hyungsub Kim, Yong-Soon Cho, Sungpil Han, Shi Hyang Lee, Kyun-Seop Bae, Jina Jung, Sung Hee Hong, Hyeong-Seok Lim
Publikováno v:
Drug Design, Development and Therapy. 17:1107-1114
Moon Hee Lee,1 Seok-Kyu Yoon,1 Hyungsub Kim,2 Yong-Soon Cho,3 Sungpil Han,4 Shi Hyang Lee,1 Kyun-Seop Bae,1 Jina Jung,5 Sung Hee Hong,5 Hyeong-Seok Lim1 1Department of Clinical Pharmacology and Therapeutics, Asan Medical Center, University of Ulsan,
Autor:
Park, Maria, Suein Choi, Sungpil Han, Wonsuk Shin, Anhye Kim, Seunghoon Han, Bomin Kim, Yeji Lim, Hyounggyoon Yoo
Publikováno v:
Translational & Clinical Pharmacology; Dec2023, Vol. 31 Issue 4, p226-237, 12p
Publikováno v:
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
Fixed-dose combinations development requires pharmacokinetic drug-drug interaction (DDI) studies between active ingredients. For some drugs, pharmacokinetic properties such as long half-life or delayed distribution, make it difficult to conduct such
Autor:
Sungpil Han, Hee Youn Choi, Yo Han Kim, SeungChan Choi, Seokuee Kim, Ji Yeon Nam, Bongtae Kim, Geun Seog Song, Hyeong-Seok Lim, Kyun-Seop Bae
Publikováno v:
Gut and liver.
Tegoprazan, a novel potassium-competitive acid blocker, is expected to overcome the limitations of proton pump inhibitors and effectively control nocturnal acid breakthrough. To evaluate the pharmacodynamics of tegoprazan versus dexlansoprazole regar
Autor:
Hyeong-Seok Lim, Hee Youn Choi, Kyun-Seop Bae, Kim Jongwoo, Yo Han Kim, Kim Jeongmin, Joonwoo Nam, Sungpil Han, Dong-Jun Soh
Publikováno v:
Drug Design, Development and Therapy
Background Poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor has therapeutic potential for acute ischemic stroke by suppressing microglial activation and facilitating neuroprotection. In this first-in-human study, we investigate the safety, tolerabil
Publikováno v:
International journal of stem cells.
Despite long-term research achievements, the development of cell therapy (CT) products remains challenging. This is because the risks experienced by the subject and therapeutic effects in the clinical trial stage are unclear due to the various uncert