Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Sungpil Cho"'
Autor:
Seungbin Cha, Sun Hwa Lee, Sung Hun Kang, Mohammad Nazmul Hasan, Young Jun Kim, Sungpil Cho, Yong-Kyu Lee
Publikováno v:
Biomaterials Research, Vol 22, Iss 1, Pp 1-12 (2018)
Abstract Background Diabetes mellitus (DM) is a chronic progressive metabolic disease that involves uncontrolled elevation of blood glucose levels. Among various therapeutic approaches, GLP-1 prevents type 2 diabetes mellitus (T2DM) patients from exp
Externí odkaz:
https://doaj.org/article/9f4b707a145748b7b256c660bc0dbcd3
Publikováno v:
Polymers, Vol 10, Iss 9, p 948 (2018)
Most currently available commercial vaccines are delivered by systemic injection. However, needle-free oral vaccine delivery is currently of great interest for several reasons, including the ability to elicit mucosal immune responses, ease of adminis
Externí odkaz:
https://doaj.org/article/6f2de83a7c60405186c28b9604bb40d1
Autor:
Sungpil Cho, Hongsuk Park, Elke A Jarboe, C Matthew Peterson, You Han Bae, Margit M Janát-Amsbury
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141172 (2015)
Cancer stem cells (CSCs) are a small subset of cancer cells responsible for maintenance and progression of several types of cancer. Isolation, propagation, and the differentiation of CSCs in the proper stem niches expose the intrinsic difficulties fo
Externí odkaz:
https://doaj.org/article/427b683983404797b6740707f21f4503
Autor:
S. M.Shatil Shahriar, Dong Yun Lee, Sachin S. Surwase, Yong-kyu Lee, Jeong Man An, Sungpil Cho, Mohammad Nazmul Hasan, Yeu-Chun Kim
Publikováno v:
Nano Letters. 21:4666-4675
Herein, a bile acid-inspired triple padlock oral gene delivery platform is developed, facilitating the protection of the therapeutic gene from gastrointestinal degradation, selective intestinal accumulation through a bile acid-specific transporter, a
Autor:
Seung Rim Hwang, Dong Yun Lee, Jeong Man An, Yong Hwa Hwang, Sungpil Cho, Yong-kyu Lee, S. M.Shatil Shahriar
Publikováno v:
ACS Applied Materials & Interfaces. 13:23314-23327
Intermittent subcutaneous (S.C.) injection of teriparatide [PTH (1-34)] is one of the effective therapies to cure osteoporosis. However, a long-term repeated administration of teriparatide by S.C. to the patients is highly challenging. Herein, a trip
Autor:
Yong Hwa Hwang, Sungpil Cho, Jeong Man An, Yong-kyu Lee, Mohammad Nazmul Hasan, S. M.Shatil Shahriar
Publikováno v:
ACS Applied Materials & Interfaces. 12:38925-38935
Type 2 diabetes mellitus (T2DM) is a chronic and progressive hyperglycemic condition. Glucagon-like peptide-1 (GLP1) is an incretin secreted from pancreatic β-cells and helps to produce insulin to balance the blood glucose level without the risk of
Oral siRNA delivery using dual transporting systems to efficiently treat colorectal liver metastasis
Publikováno v:
International Journal of Pharmaceutics. 555:250-258
Oral siRNA delivery is an ideal way to translate siRNA therapeutic effects in the clinic due to its ability to be administered in convenient and multiple dosages. However, an effective oral delivery system requires overcoming both a hostile gastroint
Publikováno v:
ACS applied materialsinterfaces. 13(14)
Pharmacological-based treatment approaches have been used over time to prevent postlaparotomy adhesion. However, the rapid elimination of therapeutics from the peritoneum, and their unwanted side effects, easy flow from the wound site by gravity, and
Autor:
Jeong Man, An, S M Shatil, Shahriar, Yong Hwa, Hwang, Seung Rim, Hwang, Dong Yun, Lee, Sungpil, Cho, Yong-Kyu, Lee
Publikováno v:
ACS applied materialsinterfaces. 13(20)
Intermittent subcutaneous (S.C.) injection of teriparatide [PTH (1-34)] is one of the effective therapies to cure osteoporosis. However, a long-term repeated administration of teriparatide by S.C. to the patients is highly challenging. Herein, a trip
Autor:
Nafiujjaman, Zehedina Khatun, Sungpil Cho, Kang Moo Huh, Vishnu Revuri, Yong-kyu Lee, Nurunnabi, Seungbin Cha
Publikováno v:
RSC Advances. 6:73986-74002
Bioinspired materials have received substantial attention across biomedical, biological, and drug delivery research because of their high biocompatibility and lower toxicity compared with synthetic materials. Bile acids, well-established biomimetic b