Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sunghark Kwon"'
Autor:
Sunghark Kwon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The Janus kinase (JAK) family enzymes are non-receptor tyrosine kinases that phosphorylate cytokine receptors and signal transducer and activator of transcription (STAT) proteins in the JAK-STAT signaling pathway. Considering that JAK-STAT signal tra
Externí odkaz:
https://doaj.org/article/dd36002a5532477a97b54700372510b8
Autor:
Jisub Hwang, Sun-Ha Park, Chang Woo Lee, Hackwon Do, Seung Chul Shin, Han-Woo Kim, Sung Gu Lee, Hyun Ho Park, Sunghark Kwon, Jun Hyuck Lee
Publikováno v:
IUCrJ, Vol 8, Iss 5, Pp 842-852 (2021)
MarR family proteins regulate the transcription of multiple antibiotic-resistance genes and are widely found in bacteria and archaea. Recently, a new MarR family gene was identified by genome analysis of the psychrophilic bacterium Paenisporosarcina
Externí odkaz:
https://doaj.org/article/138b293da9254f87a2e0a52c60fff346
Publikováno v:
IUCrJ, Vol 8, Iss 4, Pp 574-583 (2021)
Lipid II, the main component of the bacterial cell wall, is synthesized by the addition of UDP-N-acetylglucosamine to the UDP-N-acetylmuramic acid pentapeptide catalyzed by the glycosyltransferase MurG. Owing to its critical role in cell-wall biosynt
Externí odkaz:
https://doaj.org/article/5dc32f691ca244c6b2ff522165f4bb31
Autor:
Sunghark Kwon, Hyun Ho Park
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 1031-1039 (2019)
Transaminases (TAs) reversibly catalyze the transfer reaction of an amino group between an amino group donor and an amino group acceptor, using pyridoxal 5′-phosphate (PLP) as a cofactor. TAs are categorized according to the amino group position of
Externí odkaz:
https://doaj.org/article/d07ecf0bb8bd4a99bed9a93f1c61f105
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251067 (2021)
During the glyoxylate cycle, isocitrate lyases (ICLs) catalyze the lysis of isocitrate to glyoxylate and succinate. Itaconate has been reported to inhibit an ICL from Mycobacterium tuberculosis (tbICL). To elucidate the molecular mechanism of ICL inh
Externí odkaz:
https://doaj.org/article/9c4e927bbb4e42e8914e0d36f6ee0848
Autor:
Hyun Ji Ha, Sunghark Kwon, Eui Man Jeong, Chang Min Kim, Ki Baek Lee, In-Gyu Kim, Hyun Ho Park
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204707 (2018)
Multi-functional transglutaminase 2 (TG2), which possesses protein cross-linking and GTP hydrolysis activities, is involved in various cellular processes, including apoptosis, angiogenesis, wound healing, and neuronal regeneration, and is associated
Externí odkaz:
https://doaj.org/article/d831a87bc7a04f549290e298e7da6853
Publikováno v:
Crystals, Vol 9, Iss 10, p 504 (2019)
Soluble fumarate reductase is essential for survival under anaerobic conditions. This enzyme can maintain the redox balance in the cell by catalyzing the reduction of fumarate to succinate. Although the overall reaction mechanism of soluble fumarate
Externí odkaz:
https://doaj.org/article/3fd6e05a29e04c6b911874bf31cd60f9
Autor:
Sunghark Kwon
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3121
Volume 24
Issue 4
Pages: 3121
Flavin adenine dinucleotide synthetases (FADSs) catalyze FAD biosynthesis through two consecutive catalytic reactions, riboflavin (RF) phosphorylation and flavin mononucleotide (FMN) adenylylation. Bacterial FADSs have RF kinase (RFK) and FMN adenyly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3957eaebe2d28bc1bfd558cbf8062e
Autor:
Jisub Hwang, Jun Hyuck Lee, Min Ju Lee, Hyun Ji Ha, Hyun Ho Park, Sunghark Kwon, Ji Hye Sung, Yong Jun Kang
Publikováno v:
Biochemical and Biophysical Research Communications. 585:48-54
Sugar isomerases (SIs) catalyze the reversible conversion of aldoses to ketoses. A novel putative SI gene has been identified from the genome sequence information on the psychrophilic bacterium Paenibacillus sp. R4. Here, we report the crystal struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635c7166e49c5119c3b1e5a8fc4840e1
https://doi.org/10.1016/j.bbrc.2021.11.026
https://doi.org/10.1016/j.bbrc.2021.11.026
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
The CIDE domain was initially identified in apoptotic nucleases and now forms a highly conserved family with diverse functions ranging from cell death to lipid metabolism. Based on structural determination of the DREP3 domain, it is suggested that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f483130178c14c9f09832d5e73dd48
https://doi.org/10.1107/s2059798321010767
https://doi.org/10.1107/s2059798321010767