Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sungbo Hwang"'
Publikováno v:
ACS Omega, Vol 6, Iss 23, Pp 15361-15373 (2021)
Externí odkaz:
https://doaj.org/article/32b8d6968ac54907b533b4def88b088b
Publikováno v:
Journal of Cheminformatics, Vol 12, Iss 1, Pp 1-17 (2020)
Abstract Computer-aided research on the relationship between molecular structures of natural compounds (NC) and their biological activities have been carried out extensively because the molecular structures of new drug candidates are usually analogou
Externí odkaz:
https://doaj.org/article/e84d7d95739b437ba38ea19d73cae166
Investigation of Hot Spot Region in XIAP Inhibitor Binding Site by Fragment Molecular Orbital Method
Autor:
Hocheol Lim, Xuemei Jin, Jongwan Kim, Sungbo Hwang, Ki Beom Shin, Jiwon Choi, Ky-Youb Nam, Kyoung Tai No
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 1217-1225 (2019)
X-linked inhibitor of apoptosis protein (XIAP) is an important regulator of cancer cell survival whose BIR3 domain (XIAP-BIR3) recognizes the Smac N-terminal tetrapeptide sequence (AVPI), making it an attractive protein-protein interaction (PPI) targ
Externí odkaz:
https://doaj.org/article/8a0ad527699447c4abc973ae10dfc394
Autor:
Geum Seok Jeong, Prima F. Hillman, Myung-Gyun Kang, Sungbo Hwang, Jong-Eun Park, Sang-Jip Nam, Daeui Park, Hoon Kim
Publikováno v:
Journal of Fungi, Vol 7, Iss 10, p 876 (2021)
Using 126 endogenous lichen fungus (ELF) extracts, inhibitory activities against monoamine oxidases (MAOs) and cholinesterases (ChEs) were evaluated. Among them, extract ELF29 of the endogenous fungus Diaporthe mahothocarpus of the lichen Cladonia sy
Externí odkaz:
https://doaj.org/article/b4f90dabc95f46ed9c92dd3f69e7c495
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3659 (2021)
Six kuwanon derivatives (A/B/C/E/H/J) extracted from the roots of Morus alba L. were evaluated to determine their cyclooxygenase (COX)-1 and 2 inhibitory effects. Cyclooxygenase (COX) is known as the target enzyme of nonsteroidal anti-inflammatory dr
Externí odkaz:
https://doaj.org/article/6f47e17002b24c22a3d23cb19678479d
Publikováno v:
Molecular & Cellular Toxicology. 18:299-309
Background Dog-associated infections are related to more than 70 human diseases. Given that the health diagnosis of a dog requires expertise of the veterinarian, an artificial intelligence model for detecting dog diseases could significantly reduce t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4833565234e4b56e1b63b9c151e9d984
https://doi.org/10.1007/s13273-022-00249-7
https://doi.org/10.1007/s13273-022-00249-7
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 23, Pp 15361-15373 (2021)
ACS Omega, Vol 6, Iss 23, Pp 15361-15373 (2021)
The objective of this study was to develop a robust prediction model for the infinite dilution activity coefficients (γ∞) of organic molecules in diverse ionic liquid (IL) solvents. Electrostatic, hydrogen bond, polarizability, molecular structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a69890fadf347a0aa3eee1ce49780f
http://europepmc.org/articles/PMC8210453
http://europepmc.org/articles/PMC8210453
Autor:
Hyun Kil Shin, Hang-Suk Chun, Sangwoo Lee, Se-Myo Park, Daeui Park, Myung-Gyun Kang, Sungbo Hwang, Jung-Hwa Oh, Hyoung-Yun Han, Woo-Keun Kim, Seokjoo Yoon
Publikováno v:
Bioinformatics (Oxford, England). 38(18)
Summary Drug-induced liver injury (DILI) is a challenging endpoint in predictive toxicology because of the complex reactive metabolites that cause liver damage and the wide range of mechanisms involved in the development of the disease. ToxSTAR provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f02001f45ed4845fc117aacdf26aa2
https://pubmed.ncbi.nlm.nih.gov/35900148
https://pubmed.ncbi.nlm.nih.gov/35900148
Publikováno v:
Journal of chemical information and modeling. 62(7)
In the past 2 years, since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), multiple SARS-CoV-2 variants have emerged. Whenever a new variant emerges, considerable time is required to analyze the binding affinity of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c9815f4220fa55f5616dbee6bf976c
https://pubmed.ncbi.nlm.nih.gov/35312321
https://pubmed.ncbi.nlm.nih.gov/35312321
Investigation of Hot Spot Region in XIAP Inhibitor Binding Site by Fragment Molecular Orbital Method
Autor:
Ki Beom Shin, Hocheol Lim, Jongwan Kim, Ky Youb Nam, Jiwon Choi, Xuemei Jin, Kyoung Tai No, Sungbo Hwang
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1217-1225 (2019)
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1217-1225 (2019)
X-linked inhibitor of apoptosis protein (XIAP) is an important regulator of cancer cell survival whose BIR3 domain (XIAP-BIR3) recognizes the Smac N-terminal tetrapeptide sequence (AVPI), making it an attractive protein-protein interaction (PPI) targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846bf79946fc3f084b4f54bfe22d3220
https://doi.org/10.1016/j.csbj.2019.08.004
https://doi.org/10.1016/j.csbj.2019.08.004