Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sung-Yong Hwang"'
Autor:
Hanna Witwicka, Sung-Yong Hwang, Pablo Reyes-Gutierrez, Hong Jia, Paul E Odgren, Leah Rae Donahue, Mark J Birnbaum, Paul R Odgren
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128275 (2015)
The fusion of monocyte/macrophage lineage cells into fully active, multinucleated, bone resorbing osteoclasts is a complex cell biological phenomenon that utilizes specialized proteins. OC-STAMP, a multi-pass transmembrane protein, has been shown to
Externí odkaz:
https://doaj.org/article/73882b023b3642ad816a40ca46f87713
Autor:
Sung-Yong Hwang, James W. Putney
Publikováno v:
The FASEB Journal. 26:1484-1492
Bone diseases such as postmenopausal osteoporosis are primarily caused by excessive formation and activity of osteoclasts (OCLs). Receptor activator of nuclear factor-κB ligand (RANKL) is a key initiating cytokine for OCL differentiation and functio
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 39:1852-1862
Differential intracellular distribution of the three pharmacologically and biophysically distinct types of IP3Rs can lead to different subcellular Ca2+ transients each coupled to discrete intracellular functions. Here, we report the functional locali
Autor:
Paul E. Odgren, Hanna Witwicka, Pablo Reyes-Gutierrez, Paul R. Odgren, Leah Rae Donahue, Mark J. Birnbaum, Sung-Yong Hwang, Hong Jia
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128275 (2015)
PLoS ONE
PLoS ONE
The fusion of monocyte/macrophage lineage cells into fully active, multinucleated, bone resorbing osteoclasts is a complex cell biological phenomenon that utilizes specialized proteins. OC-STAMP, a multi-pass transmembrane protein, has been shown to
Autor:
Peter Koulen, Masahiko Tanaka, Kaoru Inokuchi, Jo-Ann S. Yannazzo, Nathalie McClung, Sung-Yong Hwang, Tohru Marunouchi, R. Scott Duncan
Publikováno v:
FEBS Letters. 580:6145-6150
Neurons expand, sustain or prune their dendritic trees during ontogenesis [Cline, H.T. (2001). Dendritic arbor development and synaptogenesis. Curr. Opin. Neurobiol. 11, 118–126; Wong, W.T. and Wong, R.O.L. (2000) Rapid dendritic movements during s
Autor:
Sung-Yong Hwang, Ji-yeon Hwang, Martha E. Stokely, Michael A. King, Kaoru Inokuchi, Peter Koulen, Betty Fan
Publikováno v:
Journal of Neuroscience Research. 84:1727-1737
Polycystin-1 (PC-1) has been identified as critical to development of the nervous system, but the significance of PC-1 expression in neurons remains undefined, and little is known of its roles outside the kidney, where mutation results in autosomal d
Publikováno v:
Bone Abstracts.
Autor:
James W. Putney, Julie F. Foley, Takuro Numaga-Tomita, John G. Petranka, Gary S. Bird, Sung-Yong Hwang
Publikováno v:
Cell calcium. 52(6)
Store-operated Ca(2+) entry (SOCE) is a major Ca(2+) influx pathway in most non-excitable cell types and Orai1 was recently identified as an essential pore-subunit of SOCE channels. Here we investigate the physiological role of Orai1 in bone homeosta
Autor:
Sung-Yong Hwang, James W. Putney
Publikováno v:
Biochimica et biophysica acta. 1813(5)
It has long been known that many bone diseases, including osteoporosis, involve abnormalities in osteoclastic bone resorption. As a result, there has been intense study of the mechanisms that regulate both the differentiation and bone resorbing funct