Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Sung-Won Shin"'
Autor:
Sun Up Noh, Jinyeong Lim, Sung-Won Shin, Yeeun Kim, Woong-Yang Park, Ines Batinic-Haberle, Changhoon Choi, Won Park
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 477 (2024)
Manganese porphyrins reportedly exhibit synergic effects when combined with irradiation. However, an in-depth understanding of intratumoral heterogeneity and immune pathways, as affected by Mn porphyrins, remains limited. Here, we explored the mechan
Externí odkaz:
https://doaj.org/article/313101eaefc24be3a8dd5c5e871dac6f
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 35, Iss , Pp 100862- (2023)
Intrinsic or acquired radioresistance often limits the efficacy of radiation therapy (RT), thereby leading to local control failure. Cancerous cells have abnormal pH dynamics due to high metabolic demands, but it is unclear how pH dynamics contribute
Externí odkaz:
https://doaj.org/article/417343b4bec84bda8ffa875369fd7d4a
Autor:
Yeeun Kim, Kyunghee Park, Yeon Jeong Kim, Sung-Won Shin, Yeon Joo Kim, Changhoon Choi, Jae Myoung Noh
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15539 (2022)
Although the combination of radiotherapy and immunotherapy has proven to be effective in lung cancer treatment, it may not be sufficient to fully activate the antitumor immune response. Here, we investigated whether entinostat, a histone deacetylase
Externí odkaz:
https://doaj.org/article/c98f0496a8fc44eaa6632ca25f690637
Autor:
Yoo-Young Lee, Young-Jae Cho, Sung-won Shin, Changhoon Choi, Ji-Yoon Ryu, Hye-Kyung Jeon, Jung-Joo Choi, Jae Ryoung Hwang, Chel Hun Choi, Tae-Joong Kim, Byoung- Gie Kim, Duk-Soo Bae, Won Park, Jeong-Won Lee
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Although the concurrent use of a chemotherapeutic agent and radiotherapy improves survival in patients with locally advanced or recurrent cervical cancer, severe side effects related to chemotherapy are frequent and may result in a low quali
Externí odkaz:
https://doaj.org/article/37fc5faa39024327940cb72635355416
Autor:
Sung-Won Shin, Changhoon Choi, Hakyoung Kim, Yeeun Kim, Sohee Park, Shin-Yeong Kim, Ines Batinic-Haberle, Won Park
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1769 (2021)
Tumor migration and invasion induced by the epithelial-to-mesenchymal transition (EMT) are prerequisites for metastasis. Here, we investigated the inhibitory effect of a mimic of superoxide dismutase (SOD), cationic Mn(III) ortho-substituted N-n-hexy
Externí odkaz:
https://doaj.org/article/5b507cbe7fe8409d8046bef1324cff8d
Autor:
Jeong Il Yu, Changhoon Choi, Sung-Won Shin, Arang Son, Ga-Haeng Lee, Shin-Yeong Kim, Hee Chul Park
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Although efficacy of combined histone deacetylase (HDAC) inhibitors and conventional photon radiotherapy is being tested in clinical trials, their combined effect with proton beam radiotherapy has yet to be determined. Here, we compared comb
Externí odkaz:
https://doaj.org/article/4cec5c5dba794db6be2620d3f5dbff9f
Autor:
Kyungmi Yang, Changhoon Choi, Hayeong Cho, Won-Gyun Ahn, Shin-Yeong Kim, Sung-Won Shin, Yeeun Kim, Taekyu Jang, Nohyun Lee, Hee Chul Park
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1811 (2021)
Immunomodulation by radiotherapy (RT) is an emerging strategy for improving cancer immunotherapy. Nanomaterials have been employed as innovative tools for cancer therapy. This study aimed to investigate whether mesoporous silica nanoparticles (MSNs)
Externí odkaz:
https://doaj.org/article/ad7a455232484d50ab02c2fd50826ad4
Autor:
Changhoon Choi, Arang Son, Ga-Haeng Lee, Sung-Won Shin, Sohee Park, Sang Hee Ahn, Yoonsun Chung, Jeong Il Yu, Hee Chul Park
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218049 (2019)
Recent studies have highlighted the implications of genetic variations in the relative biological effectiveness (RBE) of proton beam irradiation over conventional X-ray irradiation. Proton beam radiotherapy is a reasonable radiotherapy option for hep
Externí odkaz:
https://doaj.org/article/c645d8303edc4e66a2c54dbac562295c
Autor:
Sung-Won Shin, Kyungmi Yang, Miso Lee, Jiyoung Moon, Arang Son, Yeeun Kim, Suha Choi, Do-hyung Kim, Changhoon Choi, Nohyun Lee, Hee Chul Park
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2637 (2021)
We evaluated the effect of manganese ferrite nanoparticles (MFN) on radiosensitization and immunologic responses using the murine hepatoma cell line Hepa1-6 and the syngeneic mouse model. The clonogenic survival of Hepa1-6 cells was increased by hypo
Externí odkaz:
https://doaj.org/article/1513a1817b414dd59959ad993447cf06
Publikováno v:
Marine Drugs, Vol 18, Iss 10, p 500 (2020)
Radiation therapy (RT) is an effective local treatment for unresectable hepatocellular carcinoma (HCC), but there are currently no predictive biomarkers to guide treatment decision for RT or adjuvant systemic drugs to be combined with RT for HCC pati
Externí odkaz:
https://doaj.org/article/24594c3aba17428689a6f339493871ac