Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Sung-Hack Lee"'
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 10, Iss 4 (2007)
Purpose. To investigate the role of intestinal breast cancer resistant protein (BCRP) in the absorption and disposition of topotecan (TPT) using novobiocin (NOV) as a specific inhibitor. Methods. Transporter inhibition specificity of NOV was assessed
Externí odkaz:
https://doaj.org/article/47d17b595b2a4fd6ab1c082f04624561
Analysis of Rainfall Quantile Based on Shared Socioeconomic Pathways (SSPs) Scenarios in South Korea
Publikováno v:
Proceedings of the 39th IAHR World Congress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcb84d86c29df9253ec1d35ea9ede222
https://doi.org/10.3850/iahr-39wc252171192022160
https://doi.org/10.3850/iahr-39wc252171192022160
Publikováno v:
Journal of The Korean Society of Agricultural Engineers. 59:31-43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e757f75d44758a7d07c4bdc92837fd0a
https://doi.org/10.5389/ksae.2017.59.1.031
https://doi.org/10.5389/ksae.2017.59.1.031
Autor:
Aeri Kim, Kyungha Chung, Kim Tae-Hun, Sun-Hwa Lee, Sung-Hack Lee, Suk-Kyoon Yoon, Hee Dong Park, Jihye Lee, Seungyup Paek, Bongchan Kim, Eunice EunKyeong Kim
Publikováno v:
Molecular Pharmaceutics. 13:1197-1205
LB30870, a new direct thrombin inhibitor, showed 80% reduction in oral bioavailability in fed state. The present study aims to propose trypsin binding as a mechanism for such negative food effect and demonstrate a prodrug approach to mitigate food ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c229aa382fe2de7f1eb5e3d44ec9bcf
https://doi.org/10.1021/acs.molpharmaceut.5b00637
https://doi.org/10.1021/acs.molpharmaceut.5b00637
Autor:
Sung-Hack Lee, Sandra García-Medina, Ignacio Conde-Carmona, Juan Manuel Jiménez-Vargas, Alberto Martínez-Muñoz
Publikováno v:
Clinical therapeutics. 40(10)
Purpose The aim of this study was to assess the pharmacokinetic interactions between a newly developed dipeptidyl peptidase (DPP)-4 inhibitor, gemigliptin, and metformin in healthy Mexican male volunteers, and the differences in the pharmacokinetic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be20c8167ddb973f8909462112b2c7a5
https://pubmed.ncbi.nlm.nih.gov/30249366
https://pubmed.ncbi.nlm.nih.gov/30249366
Publikováno v:
Journal of The Korean Society of Agricultural Engineers. 57:173-183
The aim of this study was to develop a soil moisture simulation model equipped with meteorological data enhanced by WRF (Weather Research and Forecast) model, and this soil moisture model was applied for quantifying soil moisture content and irrigati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::349c6462f7b4146bc93e76eba4fa1bdb
https://doi.org/10.5389/ksae.2015.57.6.173
https://doi.org/10.5389/ksae.2015.57.6.173
Publikováno v:
Journal of The Korean Society of Agricultural Engineers. 56:55-64
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b5e8ff6904c946ee7bcfad6d2b21b3b
https://doi.org/10.5389/ksae.2014.56.3.055
https://doi.org/10.5389/ksae.2014.56.3.055
Publikováno v:
Xenobiotica. 44:627-634
1. The absorption, distribution, metabolism and excretion of a novel dipeptidyl peptidase IV inhibitor, gemigliptin, were examined following single oral administration of 14C-labeled gemigliptin to rats.2. The 14C-labeled gemigliptin was rapidly abso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e35f001d55870f7fea502e33ceab62
https://doi.org/10.3109/00498254.2013.873156
https://doi.org/10.3109/00498254.2013.873156
Publikováno v:
Xenobiotica. 44:522-530
1. Gemigliptin (formerly known as LC15-0444) is a newly developed dipeptidyl peptidase 4 inhibitor for the treatment of type 2 diabetes. Following oral administration of 50 mg (5.4 MBq) [(14)C]gemigliptin to healthy male subjects, absorption, metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348a16a311573125abccbdfd122d981a
https://doi.org/10.3109/00498254.2013.865856
https://doi.org/10.3109/00498254.2013.865856
Publikováno v:
Journal of Pharmaceutical Investigation. 43:197-203
This study was to examine the pharmacokinetics of LB30870, a thrombin inhibitor, after IV and oral administration to rats, dogs, and monkeys. In rats and dogs, LB30870 showed linear pharmacokinetics after IV and oral administration. The oral bioavail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b70b79a0f183eaf160754b89566eac3a
https://doi.org/10.1007/s40005-013-0066-3
https://doi.org/10.1007/s40005-013-0066-3