Metabolic Engineering of Corynebacterium glutamicum for High‐Level Ectoine Production: Design, Combinatorial Assembly, and Implementation of a Transcriptionally Balanced Heterologous Ectoine Pathway

Autor: Timo Mühlhaus, Sung S Yim, David Zimmer, Michael Schroda, Lukas Jungmann, Gideon Gießelmann, Eun Jung Jeon, Ki Jun Jeong, Michael Kohlstedt, Frederik Sommer, Demian Dietrich, Judith Becker, Christoph Wittmann

Publikováno v: Biotechnology Journal. 14:1800417

Ectoine is formed in various bacteria as cell protectant against all kinds of stress. Its preservative and protective effects have enabled various applications in medicine, cosmetics, and biotechnology, and ectoine therefore has high commercial value

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d9c5687b71602d0753e617cf033ec0
https://doi.org/10.1002/biot.201800417

Quantitative muscle ultrasound detects disease progression in Duchenne muscular dystrophy.

Autor: Zaidman CM; Department of Neurology, Washington University in St Louis, St Louis, MO., Wu JS; Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA., Kapur K; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA., Pasternak A; Department of Physical Therapy Services and Occupational Therapy Services, Boston Children's Hospital, Boston, MA., Madabusi L; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA., Yim S; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA., Pacheck A; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA., Szelag H; Department of Neurology, Washington University in St Louis, St Louis, MO., Harrington T; Department of Neurology, Washington University in St Louis, St Louis, MO., Darras BT; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA., Rutkove SB; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA.

Publikováno v: Annals of neurology [Ann Neurol] 2017 May; Vol. 81 (5), pp. 633-640. Date of Electronic Publication: 2017 May 04.

Loss of electrical anisotropy is an unrecognized feature of dystrophic muscle that may serve as a convenient index of disease status.

Autor: Rutkove SB; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA. Electronic address: srutkove@bidmc.harvard.edu., Wu JS; Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA., Zaidman C; Department of Neurology, Washington University in St. Louis, 660 S Euclid Ave, St. Louis, MO 63110, USA., Kapur K; Department of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA., Yim S; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA., Pasternak A; Department of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA., Madabusi L; Department of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA., Szelag H; Department of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA., Harrington T; Department of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA., Li J; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA., Pacheck A; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA., Darras BT; Department of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.

Publikováno v: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology [Clin Neurophysiol] 2016 Dec; Vol. 127 (12), pp. 3546-3551. Date of Electronic Publication: 2016 Oct 13.

Tongue electrical impedance in amyotrophic lateral sclerosis modeled using the finite element method.

Autor: Pacheck A; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Mijailovic A; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Yim S; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Li J; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Green JR; MGH Institute of Health Professions, Boston, MA 02129, USA., McIlduff CE; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Rutkove SB; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address: srutkove@bidmc.harvard.edu.

Publikováno v: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology [Clin Neurophysiol] 2016 Mar; Vol. 127 (3), pp. 1886-90. Date of Electronic Publication: 2015 Dec 11.

Evaluation of Electrical Impedance as a Biomarker of Myostatin Inhibition in Wild Type and Muscular Dystrophy Mice.

Autor: Sanchez B; Department of Neurology, Division of Neuromuscular Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215-5491, United States of America., Li J; Department of Neurology, Division of Neuromuscular Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215-5491, United States of America., Yim S; Department of Neurology, Division of Neuromuscular Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215-5491, United States of America., Pacheck A; Department of Neurology, Division of Neuromuscular Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215-5491, United States of America., Widrick JJ; Division of Genetics and Genomics, Boston Children's Hospital, Harvard Medical School, Boston, MA 02215-5491, United States of America., Rutkove SB; Department of Neurology, Division of Neuromuscular Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215-5491, United States of America.

Publikováno v: PloS one [PLoS One] 2015 Oct 20; Vol. 10 (10), pp. e0140521. Date of Electronic Publication: 2015 Oct 20 (Print Publication: 2015).