Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Sung Kweon Cho"'
Autor:
Chamlee Cho, Beomsu Kim, Dan Say Kim, Mi Yeong Hwang, Injeong Shim, Minku Song, Yeong Chan Lee, Sang-Hyuk Jung, Sung Kweon Cho, Woong-Yang Park, Woojae Myung, Bong-Jo Kim, Ron Do, Hyon K. Choi, Tony R. Merriman, Young Jin Kim, Hong-Hee Won
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Hyperuricemia is an essential causal risk factor for gout and is associated with cardiometabolic diseases. Given the limited contribution of East Asian ancestry to genome-wide association studies of serum urate, the genetic architecture of s
Externí odkaz:
https://doaj.org/article/c397e0e4e3324b75a714a797657f8e2d
Autor:
Yu Toyoda, Sung Kweon Cho, Velibor Tasic, Kateřina Pavelcová, Jana Bohatá, Hiroshi Suzuki, Victor A. David, Jaeho Yoon, Anna Pallaiova, Jana Šaligová, Darryl Nousome, Raul Cachau, Cheryl A. Winkler, Tappei Takada, Blanka Stibůrková
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Renal hypouricemia (RHUC) is a pathological condition characterized by extremely low serum urate and overexcretion of urate in the kidney; this inheritable disorder is classified into type 1 and type 2 based on causative genes encoding physiologicall
Externí odkaz:
https://doaj.org/article/ecdfaf66f7f345c7b069c74d26b40df9
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
We reviewed all currently available ULT, as well as any medications in development using following databases: United States Food and Drug Administration (FDA), European Medicines Agency (EMA), Japanese Pharmaceutical and Medical Devices Agency (PMDA)
Externí odkaz:
https://doaj.org/article/04ad5a141790479fa67e845851f7debe
Autor:
Do Hyeon Cha, Heon Yung Gee, Raul Cachau, Jong Mun Choi, Daeui Park, Sun Ha Jee, Seungho Ryu, Kyeong Kyu Kim, Hong-Hee Won, Sophie Limou, Woojae Myung, Cheryl A. Winkler, Sung Kweon Cho
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract Differentiating between inherited renal hypouricemia and transient hypouricemic status is challenging. Here, we aimed to describe the genetic background of hypouricemia patients using whole-exome sequencing (WES) and assess the feasibility f
Externí odkaz:
https://doaj.org/article/439031d527bb4924b5f4d7dc8ff62cb2
Autor:
Yoojin Lee, Jennifer Hwang, Shaan H. Desai, Xiaobai Li, Christopher Jenkins, Jeffrey B. Kopp, Cheryl A. Winkler, Sung Kweon Cho
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 9, p 2468 (2022)
Objective: Current guidelines for gout recommend a treat-to-target approach with serum uric acid (SUA). However, there is little evidence for the dose-dependent effects of urate-lowering therapy (ULT). Herein, we analyzed the reported SUA-lowering ef
Externí odkaz:
https://doaj.org/article/3c71ff1f2fb54317aef83f468a9677de
Autor:
Kiwon Kim, Soyeon Kim, Woojae Myung, Injeong Shim, Hyewon Lee, Beomsu Kim, Sung Kweon Cho, Joohyun Yoon, Doh Kwan Kim, Hong-Hee Won
Publikováno v:
Brain Sciences, Vol 11, Iss 8, p 1042 (2021)
Background and objectives: Parkinson’s disease (PD) and schizophrenia often share symptomatology. Psychotic symptoms are prevalent in patients with PD, and similar motor symptoms with extrapyramidal signs are frequently observed in antipsychotic-na
Externí odkaz:
https://doaj.org/article/5d8e330a73d44730af7a01dfdae53efa
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 3, p 296 (2019)
The impact of menopausal transition on change of serum uric acid level remains unknown. The present study evaluated the relationship of menopausal stages with prevalent hyperuricemia in middle-aged women. This cross-sectional study included 58,870 mi
Externí odkaz:
https://doaj.org/article/6a4f494929634ab5a8f10c60ece3b3b3
BACKGROUND It is widely accepted that metabolic syndrome is associated with hyperuricemia. However, factors affecting this association remain unclear. OBJECTIVE To explore the secular trend of hyperuricemia and investigate associations between compon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::152ea859d146fd623298223211143ddd
https://doi.org/10.2196/preprints.47727
https://doi.org/10.2196/preprints.47727
Publikováno v:
Chemico-Biological Interactions. 373:110378
Autor:
Hong-Hee Won, Woojae Myung, Hyung Lae Kim, Han Na Kim, Yoosoo Chang, Sung Kweon Cho, Cheryl A. Winkler, Seungho Ryu, Beomsu Kim, Po-Hsiu Kuo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Increased serum uric acid (SUA) levels cause gout and are associated with multiple diseases, including chronic kidney disease. Previous genome-wide association studies (GWAS) have identified more than 180 loci that contribute to SUA levels. Here, we