Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sung Hae Lee Kang"'
Autor:
Carlos A. Bacino, Sung Hae Lee Kang, Oleg A. Shchelochkov, Roberto T. Zori, Fernando Scaglia, Ashley M. Holder, Daryl A. Scott, Amy M. Breman, Margaret J. Wat, Aditi I Dagli, Sau Wai Cheung
Publikováno v:
American Journal of Medical Genetics Part A. :1661-1677
Recurrent interstitial deletion of a region of 8p23.1 flanked by the low copy repeats 8p-OR-REPD and 8p-OR-REPP is associated with a spectrum of anomalies that can include congenital heart malformations and congenital diaphragmatic hernia (CDH). Hapl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47778bb6d779da12cb45b62622504edb
https://doi.org/10.1002/ajmg.a.32896
https://doi.org/10.1002/ajmg.a.32896
Autor:
Robert T. Zori, Jörg Bungert, Philip J. Laipis, Kenneth I. Berns, Sung-Hae Lee Kang, Padraic P. Levings, Felicie F. Andersen
Publikováno v:
Genes to Cells. 9:1043-1053
Expression constructs are subject to position-effects in transgenic assays unless they harbour elements that protect them from negative or positive influences exerted by chromatin at the site of integration. Locus control regions (LCRs) and boundary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316ab69a3f42ad8f7ea7c9dd8b3ba1a2
https://doi.org/10.1111/j.1365-2443.2004.00788.x
https://doi.org/10.1111/j.1365-2443.2004.00788.x
Autor:
Meredith A. Hill, Sung Hae Lee Kang, Jörg Bungert, James Douglas Engel, Padraic P. Levings, Valerie J. Crusselle, Karen F. Vieira
Publikováno v:
Journal of Biological Chemistry. 279:50350-50357
Erythroid-specific, high level expression of the beta-globin genes is regulated by the locus control region (LCR), composed of multiple DNase I-hypersensitive sites and located far upstream of the genes. Recent studies have shown that LCR core elemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0abaf98b8d24978a1a98bb3df3936c5
https://doi.org/10.1074/jbc.m408883200
https://doi.org/10.1074/jbc.m408883200
Publikováno v:
Molecular and Cellular Biology. 23:4150-4161
Establishment and maintenance of differential chromatin structure between transcriptionally competent and repressed genes are critical aspects of transcriptional regulation. The elements and mechanisms that mediate formation and maintenance of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a478376899f73eb09fcce19889ce169
https://doi.org/10.1128/mcb.23.12.4150-4161.2003
https://doi.org/10.1128/mcb.23.12.4150-4161.2003
Autor:
Karen F. Vieira, Robert G. Roeder, Ara Aslanian, Jörg Bungert, Sung-Hae Lee Kang, Martin Teichmann, Kelly M. Leach
Publikováno v:
Nucleic Acids Research. 31:1292-1301
The human beta-globin gene is abundantly expressed specifically in adult erythroid cells. Stage-specific transcription is regulated principally by promoter proximal cis-regulatory elements. The basal promoter contains a non-canonical TATA-like motif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7e833d9a967312e214446721f98803
https://doi.org/10.1093/nar/gkg209
https://doi.org/10.1093/nar/gkg209
Publikováno v:
American journal of medical genetics. Part A. (7)
Cardiac malformations are commonly seen in individuals with terminal and interstitial deletions involving chromosome band 7p22. Although these malformations represent a significant cause of morbidity, the dosage-sensitive gene(s) that underlie these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2321254b4415cad5deb1dc0ab2a6bc44
https://pubmed.ncbi.nlm.nih.gov/21671376
https://pubmed.ncbi.nlm.nih.gov/21671376
Autor:
James R. Lupski, Seema R. Lalani, Mai T. Phung, Xin Yan Lu, Carlos A. Bacino, Kim Pham, Pawel Stankiewicz, Chad A. Shaw, Arthur L. Beaudet, Trilochan Sahoo, Sau Wai Cheung, Sarah E. Neil, Sung Hae Lee Kang, A. Craig Chinault, Ankita Patel
Publikováno v:
Pediatrics. 122(6)
OBJECTIVES. Our aim was to determine the frequency of genomic imbalances in neonates with birth defects by using targeted array-based comparative genomic hybridization, also known as chromosomal microarray analysis. METHODS. Between March 2006 and Se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fef56ce0ab687b15856f2253d6af5c5
https://pubmed.ncbi.nlm.nih.gov/19047251
https://pubmed.ncbi.nlm.nih.gov/19047251
A variety of methods are available to analyze protein-DNA interactions in vivo. Two of the most prominent of these methods are chromatin immunoprecipitation (ChIP) and in vivo footprinting. Both of these procedures have specific limitations. For exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7c7b91a78e622bf2fdc23bb652df82
https://europepmc.org/articles/PMC115298/
https://europepmc.org/articles/PMC115298/
Autor:
Xin-Yan Lu, Phung, Mai T., Shaw, Chad A., Pham, Kim, Neil, Sarah E., Patel, Ankita, Sahoo, Tricholan, Bacino, Carlos A., Stankiewicz, Pawel, Sung-Hae Lee Kang, Lalani, Seema, Chinault, A. Craig, Lupski, James R., Cheung, Sau W., Beaudet, Arthur L.
Publikováno v:
Pediatrics; Dec2008, Vol. 122 Issue 6, p1310-1318, 9p, 2 Color Photographs, 2 Charts
Publikováno v:
Molecular & Cellular Biology; Jun2003, Vol. 23 Issue 12, p4150, 12p, 13 Diagrams, 1 Chart, 4 Graphs