Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Sung‐Liang Yu"'
Autor:
Shun-Chun Yu, Tzung–Jeng Hwang, Chih-Min Liu, Hung-Yu Chan, Chian-Jue Kuo, Tsung-Tsair Yang, Jen-Pang Wang, Chen-Chung Liu, Ming H. Hsieh, Yi-Ting Lin, Yi-Ling Chien, Po-Hsiu Kuo, Ya-Wen Shih, Sung-Liang Yu, Hsuan-Yu Chen, Wei J. Chen
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Examining patients with first-episode psychosis (FEP) provides opportunities to better understand the mechanism underlying these illnesses. By incorporating quantitative measures in FEP patients, we aimed to (1) determine the base
Externí odkaz:
https://doaj.org/article/766491c4ceec42eb9ea179a0a76189b8
Autor:
Jia-Jun Wu, Jeng-Sen Tseng, Zhe-Rong Zheng, Cheng-Hsiang Chu, Kun-Chieh Chen, Mong-Wei Lin, Yen-Hsiang Huang, Kuo-Hsuan Hsu, Tsung-Ying Yang, Sung-Liang Yu, Jin-Shing Chen, Chao-Chi Ho, Gee-Chen Chang
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Patients with advanced epidermal growth factor receptor ( EGFR )-mutant lung adenocarcinoma (LAD) inevitably experience drug resistance following treatment with EGFR-tyrosine kinase inhibitors (TKIs). Objectives: We aimed to analyze the e
Externí odkaz:
https://doaj.org/article/6317e05ebe794654ab42f2e9299df02d
Autor:
Jung-Hsuan Chang, Chia-Hua Chou, Jui-Ching Wu, Keng-Mao Liao, Wei-Jia Luo, Wei-Lun Hsu, Xuan-Ren Chen, Sung-Liang Yu, Szu-Hua Pan, Pan-Chyr Yang, Kang-Yi Su
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Long-form collapsin response mediator protein-1 (LCRMP-1) belongs to the CRMP family which comprises brain-enriched proteins responsible for axon guidance. However, its role in spermatogenesis remains unclear. Here we find that LCRMP-1 is ab
Externí odkaz:
https://doaj.org/article/00a2c279cbcf45a98307696afbe0f2ab
Autor:
Keng-Mao Liao, Chih-Jung Chen, Wei-Jia Luo, Chen-Wei Hsu, Sung-Liang Yu, Pan-Chyr Yang, Kang-Yi Su
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114616- (2023)
With an aging population and the numerous health impacts associated with old age, the identification of anti-aging drugs has become an important new research direction. Although mitochondria have been recognized to affect aging, anti-aging drugs spec
Externí odkaz:
https://doaj.org/article/8b0cc430aead4eed84001df25ff600e8
Autor:
Kuo-Hsuan Hsu, Jeng-Sen Tseng, Tsung-Ying Yang, Kun-Chieh Chen, Kang-Yi Su, Sung-Liang Yu, Jeremy J. W. Chen, Yen-Hsiang Huang, Gee-Chen Chang
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The impact of strong Programmed Death-ligand 1 (PD-L1) expression on the clinical outcomes of osimertinib in treatment naïve advanced Epidermal Growth Factor Receptor (EGFR)-mutant Non-small Cell Lung Cancer (NSCLC) patients remains uncerta
Externí odkaz:
https://doaj.org/article/5efc8d5ccfbc4fecba454f08d8eff97f
Autor:
Hsien-Yu Fan, Wan-Yu Lin, Tzu-Pin Lu, Yun-Yu Chen, Justin BoKai Hsu, Sung-Liang Yu, Ta-Chen Su, Hung-Ju Lin, Yang-Ching Chen, Kuo-Liong Chien
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Background: Left ventricular mass is a highly heritable disease. Previous studies have suggested common genetic variants to be associated with left ventricular mass; however, the roles of rare variants are still unknown. We performed targeted next-ge
Externí odkaz:
https://doaj.org/article/3bc1016bddeb475b84743300bb5ebe8a
Autor:
Ya-Ling Chang, Yu-Wen Liao, Min-Hsuan Chen, Sui-Yuan Chang, Yao-Ting Huang, Bing-Ching Ho, Sung-Liang Yu
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Chang et al. show that Enterovirus 71 (EV71) infection upregulates IKKε isoform 2 (IKKε v2), which in turn activates interferon regulatory factor 7 (IRF7). This study suggests that host cells trigger IKKε isoform switching to increase the producti
Externí odkaz:
https://doaj.org/article/cf0a06bd1056452785cc2fdda4a477a3
Autor:
Yen-Hsiang Huang, Jeng-Sen Tseng, Kuo-Hsuan Hsu, Kun-Chieh Chen, Kang-Yi Su, Sung-Liang Yu, Jeremy J. W. Chen, Tsung-Ying Yang, Gee-Chen Chang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The impact of different first-line epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)s to the clinical efficacy of osimertinib in EGFR-mutant non-small-cell lung cancer (NSCLC) patients with acquired T790M was still uncl
Externí odkaz:
https://doaj.org/article/4f433cf6fdce431dbf4471b897e379b4
Autor:
Wei-Jia Luo, Sung-Liang Yu, Chia-Ching Chang, Min-Hui Chien, Ya-Ling Chang, Keng-Mao Liao, Pei-Chun Lin, Kuei-Pin Chung, Ya-Hui Chuang, Jeremy JW Chen, Pan-Chyr Yang, Kang-Yi Su
Publikováno v:
eLife, Vol 11 (2022)
Heat shock protein (HSP) 40 has emerged as a key factor in both innate and adaptive immunity, whereas the role of HLJ1, a molecular chaperone in HSP40 family, in modulating endotoxin-induced sepsis severity is still unclear. During lipopolysaccharide
Externí odkaz:
https://doaj.org/article/62ce2a444744439cad55e31b4e2ff09b
Autor:
Jia-Jun Wu, MD, Po-Hsin Lee, MD, Zhe-Rong Zheng, MD, Yen-Hsiang Huang, MD, Jeng-Sen Tseng, MD, PhD, Kuo-Hsuan Hsu, MD, Tsung-Ying Yang, MD, PhD, Sung-Liang Yu, PhD, Kun-Chieh Chen, MD, PhD, Gee-Chen Chang, MD, PhD
Publikováno v:
Medicine, Vol 101, Iss 24, p e29381 (2022)
Abstract. Kirsten rat sarcoma (KRAS) mutation (KRASm) is associated with poor prognosis in non-small cell lung cancer (NSCLC) patients. We have aimed to survey NSCLC patients harboring KRASm in Taiwan, where never-smoking lung adenocarcinoma predomin
Externí odkaz:
https://doaj.org/article/a56029aa8b94409bbb6bb1f17c32aa25