Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Suneeta Paroly"'
Autor:
Karl R. Fath, Dibyendu Dana, Jeremy Garcia, Sanjai K. Pathak, Pratikkumar Rathod, Laura Joo, Daniel A. Novoa, Suneeta Paroly, Emmanuel J. Chang, Ashif I. Bhuiyan
Publikováno v:
Bioorganic Chemistry. 85:505-514
Human cathepsin L is a ubiquitously expressed endopeptidase and is known to play critical roles in a wide variety of cellular signaling events. Its overexpression has been implicated in numerous human diseases, including highly invasive forms of canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196198e6bb2c1b2fc560786f649308d7
https://doi.org/10.1016/j.bioorg.2019.02.032
https://doi.org/10.1016/j.bioorg.2019.02.032
Autor:
Faiza Rafi, Karl R. Fath, Anna A. Dickson, Tuhin Das, Guoshen Li, Gopal Subramaniam, Sarbani Ghoshal, Sanjai K. Pathak, Pratikkumar Rathod, Dibyendu Dana, Suneeta Paroly, Ashif I. Bhuiyan, Emmanuel J. Chang
Publikováno v:
Bioorganic Chemistry. 117:105463
Human cathepsin B is a cysteine-dependent protease whose roles in both normal and diseased cellular states remain yet to be fully delineated. This is primarily due to overlapping substrate specificities and lack of unambiguously annotated physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bef6f0f68d423d40501e60e4599276b
https://doi.org/10.1016/j.bioorg.2021.105463
https://doi.org/10.1016/j.bioorg.2021.105463
Autor:
Ranjith K. Gamage, Nisar Afzal, Sanjai Kumar, Anibal R. Davalos, Kevin J. Mark, Susan A. Rotenberg, Emmanuel J. Chang, Yuriy Zavlanov, Suneeta Paroly, Juliana Huestis, Shatarupa De, Gopal Subramaniam, Dibyendu Dana, Pratikkumar Rathod
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:2975-2987
Cysteine cathepsins are an important class of enzymes that coordinate a variety of important cellular processes, and are implicated in various types of human diseases. However, small molecule inhibitors that are cell-permeable and non-peptidyl in nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a477ab015c71279a2437c2d9995d6931
https://doi.org/10.1016/j.bmc.2013.03.062
https://doi.org/10.1016/j.bmc.2013.03.062
Autor:
Shatarupa De, Nisar Afzal, Dibyendu Dana, Sanjai Kumar, Gopal Subramaniam, Suneeta Paroly, Daniel A. Novoa, Ravi S. Lankalapalli, Susan A. Rotenberg, Emmanuel J. Chang, Anibal R. Davalos, Viviana M. Torres, Pratikkumar Rathod
Publikováno v:
Chemical communications (Cambridge, England). 50(74)
A hybrid-design approach is undertaken to develop a highly potent and selective inhibitor of human cathepsin L. Studies involving human breast carcinoma MDA-MB-231 cells establish that this inhibitor can successfully block intracellular cathepsin L a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5d718f21a931b599848aee0c9132fd
https://pubmed.ncbi.nlm.nih.gov/25089379
https://pubmed.ncbi.nlm.nih.gov/25089379