Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Suneeta Chimalapati"'
Autor:
Karan Gautam Kaval, Suneeta Chimalapati, Sara D. Siegel, Nalleli Garcia, Jananee Jaishankar, Ankur B. Dalia, Kim Orth
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
It has been proposed that bacterial membrane proteins may be produced via ‘transertion’, or concurrent transcription, translation and membrane insertion from membrane-associated genes. Here, Kaval et al. provide evidence supporting that Vibrio pa
Externí odkaz:
https://doaj.org/article/ab789b966c7846f580d137892bf90145
Autor:
Alexander E. Lafrance, Suneeta Chimalapati, Nalleli Garcia Rodriguez, Lisa N. Kinch, Karan Gautam Kaval, Kim Orth
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Vibrio parahaemolyticus is among the leading causes of bacterial seafood-borne acute gastroenteritis. Like many intracellular pathogens, V. parahaemolyticus invades host cells during infection by deamidating host small Rho GTPases. The Rho G
Externí odkaz:
https://doaj.org/article/48911f898fd940b3aeaccce76c12c63a
Autor:
Suneeta Chimalapati, Marcela de Souza Santos, Alexander E Lafrance, Ann Ray, Wan-Ru Lee, Giomar Rivera-Cancel, Gonçalo Vale, Krzysztof Pawlowski, Matthew A Mitsche, Jeffrey G McDonald, Jen Liou, Kim Orth
Publikováno v:
eLife, Vol 9 (2020)
Pathogens find diverse niches for survival including inside a host cell where replication occurs in a relatively protective environment. Vibrio parahaemolyticus is a facultative intracellular pathogen that uses its type 3 secretion system 2 (T3SS2) t
Externí odkaz:
https://doaj.org/article/a8424b4b04004c88957a624611019e5f
Autor:
Claire Durmort, Giuseppe Ercoli, Elisa Ramos-Sevillano, Suneeta Chimalapati, Richard D. Haigh, Megan De Ste Croix, Katherine Gould, Jason Hinds, Yann Guerardel, Thierry Vernet, Marco Oggioni, Jeremy S. Brown
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The capsule is the dominant Streptococcus pneumoniae virulence factor, yet how variation in capsule thickness is regulated is poorly understood. Here, we describe an unexpected relationship between mutation of adcAII, which encodes a zinc up
Externí odkaz:
https://doaj.org/article/3c6b97acfd444f4693bf02410dff2bee
Autor:
Hyungjun Yang, Marcela de Souza Santos, Julia Lee, Hong T. Law, Suneeta Chimalapati, Elena F. Verdu, Kim Orth, Bruce A. Vallance
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT The Gram-negative marine bacterium Vibrio parahaemolyticus is a common cause of infectious gastroenteritis due to the ingestion of contaminated seafood. Most virulent V. parahaemolyticus strains encode two type III secretion systems (T3SS1 a
Externí odkaz:
https://doaj.org/article/7b754ce794bd415581ef5d7587332ed1
Autor:
Jimstan Periselneris, Giuseppe Ercoli, Tracey Pollard, Suneeta Chimalapati, Emilie Camberlein, Gabriella Szylar, Catherine Hyams, Gillian Tomlinson, Fernanda C. Petersen, R. Andres Floto, Mahdad Noursadeghi, Jeremy S. Brown
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT Both intracellular immune sensing and extracellular innate immune sensing have been implicated in initiating macrophage proinflammatory cytokine responses to Streptococcus pneumoniae. The S. pneumoniae capsule, a major virulence determinant,
Externí odkaz:
https://doaj.org/article/d089ef97c70043238d89741d49e77722
Autor:
Karoliina Stefanius, Kelly Servage, Marcela de Souza Santos, Hillery Fields Gray, Jason E Toombs, Suneeta Chimalapati, Min S Kim, Venkat S Malladi, Rolf Brekken, Kim Orth
Publikováno v:
eLife, Vol 8 (2019)
Cancer evolves through a multistep process that occurs by the temporal accumulation of genetic mutations. Tumor-derived exosomes are emerging contributors to tumorigenesis. To understand how exosomes might contribute to cell transformation, we utiliz
Externí odkaz:
https://doaj.org/article/d1922c4d232445f49f2061be196cfa8a
Autor:
Shilpa Basavanna, Suneeta Chimalapati, Abbas Maqbool, Bruna Rubbo, Jose Yuste, Robert J Wilson, Arthur Hosie, Abiodun D Ogunniyi, James C Paton, Gavin Thomas, Jeremy S Brown
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e49638 (2013)
Bacterial pathogens need to acquire nutrients from the host, but for many nutrients their importance during infection remain poorly understood. We have investigated the importance of methionine acquisition and synthesis for Streptococcus pneumoniae g
Externí odkaz:
https://doaj.org/article/e3b51fee0b7442328286094bf02a3649
Autor:
Suneeta Chimalapati, Jonathan M Cohen, Emilie Camberlein, Nathanael MacDonald, Claire Durmort, Thierry Vernet, Peter W M Hermans, Timothy Mitchell, Jeremy S Brown
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41393 (2012)
Lipoproteins are an important class of surface associated proteins that have diverse roles and frequently are involved in the virulence of bacterial pathogens. As prolipoproteins are attached to the cell membrane by a single enzyme, prolipoprotein di
Externí odkaz:
https://doaj.org/article/90d2cf2efffe44b5a68cc5e87c9f0763
Autor:
Amanda K. Casey, Hillery F. Gray, Suneeta Chimalapati, Genaro Hernandez, Andrew T. Moehlman, Nathan Stewart, Hazel A. Fields, Burak Gulen, Kelly A. Servage, Karoliina Stefanius, Aubrie Blevins, Bret M. Evers, Helmut Krämer, Kim Orth
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The proper balance of synthesis, folding, modification, and degradation of proteins, also known as protein homeostasis, is vital to cellular health and function. The unfolded protein response (UPR) is activated when the mechanisms maintaining protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a7572e9a56427de8aab757ba238a25
https://doi.org/10.1073/pnas.2208317119
https://doi.org/10.1073/pnas.2208317119