Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Suneela Prodduturi"'
Autor:
Venkat S. Tumuluri, Ian R. Lewis, Suneela Prodduturi, Mark S. Kemper, Bonnie A. Avery, Soumyajit Majumdar, Michael A. Repka
Publikováno v:
International Journal of Pharmaceutics. 357:77-84
The objective of this study was to investigate the use of Raman spectroscopy for the quantitative and qualitative analysis of an active ingredient in hot-melt extruded film formulations. Clotrimazole and ketoprofen were used as the active pharmaceuti
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 64:1-8
Transdermal drug delivery systems (TDDS), also known as "patches," are dosage forms designed to deliver a therapeutically effective amount of drug across a patient's skin. The adhesive of the transdermal drug delivery system is critical to the safety
Autor:
Michael A. Repka, Suneela Prodduturi, Steven P. Stodghill, William M. Kolling, Rahul V. Manek
Publikováno v:
Journal of Pharmaceutical Sciences. 94:2232-2245
Poly(ethylene oxide) (PEO) was used to prepare thin polymer films containing clotrimazole (CT) utilizing hot-melt extrusion (HME) technology. Films containing PEOs of two different molecular weights and the drug were investigated for solid-state char
Autor:
Suneela Prodduturi, William M. Kolling, Rahul V. Manek, Steven P. Stodghill, Michael A. Repka
Publikováno v:
Journal of Pharmaceutical Sciences. 93:3047-3056
Hot‐melt extrusion technology was used to prepare thin polymer films containing hydroxypropyl cellulose and clotrimazole (CT). Films containing hydroxypropyl celluloses of different molecular weight and the drug were investigated for moisture‐sor
Publikováno v:
American Journal of Drug Delivery. 2:173-192
Traditionally, per-oral delivery has been the primary route of administration for therapeutic agents targeting systemic delivery. However, oral administration subjects these compounds to extensive presystemic elimination, which may include gastrointe
Autor:
William H. Doub, Suneela Prodduturi, Lucinda F. Buhse, Benjamin J. Westenberger, Anna M. Wokovich, Nakissa Sadrieh
Publikováno v:
Journal of pharmaceutical sciences. 99(5)
The United States Food and Drug Administration (FDA) has received numerous reports of serious adverse events, including death, in patients using fentanyl transdermal systems (FTS). To gain a better understanding of these problems, the current researc
Autor:
William H. Doub, Glen J. Smith, Lucinda F. Buhse, Anna M. Wokovich, Benjamin J. Westenberger, Suneela Prodduturi
Publikováno v:
Pharmaceutical research. 26(6)
To understand and evaluate the stability and skin permeation profiles of fentanyl reservoir systems as a function of patch age. Drug release and skin permeation studies were performed using a modified USP apparatus 5 with a novel sample preparation t
Publikováno v:
AAPS PharmSciTech. 8(2)
This study was aimed at enhancing the physical stability of the drug clotrimazole (CT) and the polymer contained within hot-melt extrusion (HME) films using polymer blends of hydroxypropyl cellulose (HPC) and poly(ethylene oxide) (PEO). The HME films
Publikováno v:
Drug development and industrial pharmacy. 32(9)
The objective of this study was to investigate the influence of tartaric acid (TTA) on the bioadhesive, moisture sorption, and mechanical properties of hot-melt-extruded (HME) hydroxypropyl cellulose (HPC) films containing polymer additives. Two Kluc
Autor:
James W. McGinity, Michael A. Repka, Sri Venkata S Tumuluri, Suneela Prodduturi, Steven P. Stodghill, Michael M. Crowley, Bonnie A. Avery
Publikováno v:
Drug development and industrial pharmacy. 30(5)
The objective of the study was to demonstrate the utility of near-infrared spectroscopy (NIRS) for quantitative analysis of a model drug in hot-melt extruded film formulations. Polyethylene oxide (PEO) films with clotrimazole (CT) as a model drug wer