Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sundy N.Y. Yang"'
Autor:
Mugdha V. Joglekar, Subhshri Sahu, Wilson K.M. Wong, Sarang N. Satoor, Charlotte X. Dong, Ryan J. Farr, Michael D. Williams, Prapti Pandya, Gaurang Jhala, Sundy N.Y. Yang, Yi Vee Chew, Nicola Hetherington, Dhan Thiruchevlam, Sasikala Mitnala, Guduru V. Rao, Duvvuru Nageshwar Reddy, Thomas Loudovaris, Wayne J. Hawthorne, Andrew G. Elefanty, Vinay M. Joglekar, Edouard G. Stanley, David Martin, Helen E. Thomas, David Tosh, Louise T. Dalgaard, Anandwardhan A. Hardikar
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 5, Pp 1530-1553.e4 (2022)
Background & Aims: Pancreatic islet β-cells are factories for insulin production; however, ectopic expression of insulin also is well recognized. The gallbladder is a next-door neighbor to the developing pancreas. Here, we wanted to understand if ga
Externí odkaz:
https://doaj.org/article/3d728a223a8941f1b6deb7467c5a4e8a
The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer
Autor:
Marie A. Bogoyevitch, Sundy N.Y. Yang, David A. Jans, Chunxiao Wang, Natalie A. Borg, Sarah C. Atkinson, Alexander Lee
Publikováno v:
Antiviral research. 177
Infection by RNA viruses such as human immunodeficiency virus (HIV)-1, influenza, and dengue virus (DENV) represent a major burden for human health worldwide. Although RNA viruses replicate in the infected host cell cytoplasm, the nucleus is central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584ad6ee07bb8631affde5c4d3e0148f
https://pubmed.ncbi.nlm.nih.gov/32135219
https://pubmed.ncbi.nlm.nih.gov/32135219
Publikováno v:
Biochemical and Biophysical Research Communications. 493:1555-1559
In the absence of approved therapeutics, Zika virus (ZIKV)'s recent prolific outbreaks in the Americas, together with impacts on unborn fetuses of infected mothers, make it a pressing human health concern worldwide. Although a key player in viral rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4044db8db787018bb4abb4afdaa6e586
https://doi.org/10.1016/j.bbrc.2017.10.016
https://doi.org/10.1016/j.bbrc.2017.10.016
Autor:
Natalie A. Borg, David A. Jans, Steven M. Heaton, Sundy N.Y. Yang, Sarah C. Atkinson, Melissa N. Sweeney
Publikováno v:
Cells, Vol 8, Iss 10, p 1181 (2019)
Cells
Volume 8
Issue 10
Cells
Volume 8
Issue 10
DEAD-box helicase 3, X-linked (DDX3X) regulates the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR)-mediated antiviral response, but can also be a host factor contributing to the replication of viruses of significance to human health, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af19e7910718b05604b13e15cd67776
https://www.mdpi.com/2073-4409/8/10/1181
https://www.mdpi.com/2073-4409/8/10/1181
Autor:
Steven M. Heaton, David A. Jans, Sundy N.Y. Yang, Michelle D. Audsley, Natalie A. Borg, Sarah C. Atkinson
Publikováno v:
Cells
Cells, Vol 9, Iss 1, p 170 (2020)
Volume 9
Issue 1
Cells, Vol 9, Iss 1, p 170 (2020)
Volume 9
Issue 1
Viral disease is one of the greatest burdens for human health worldwide, with an urgent need for efficacious antiviral strategies. While antiviral drugs are available, in many cases, they are prone to the development of drug resistance. A way to over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72e517c4166f4449277edf7419e179c
https://doi.org/10.3390/cells9010170
https://doi.org/10.3390/cells9010170
Autor:
Belinda Maher, David A. Jans, Sarah C. Atkinson, Noelia Roman, Chunxiao Wang, Natalie A. Borg, Johanna E. Fraser, Sundy N.Y. Yang, Kylie M. Wagstaff, Jade K. Forwood
Publikováno v:
Cells
Volume 8
Issue 3
Cells, Vol 8, Iss 3, p 281 (2019)
Volume 8
Issue 3
Cells, Vol 8, Iss 3, p 281 (2019)
Dengue virus (DENV) threatens almost 70% of the world&rsquo
s population, with effective vaccine or therapeutic currently available. A key contributor to infection is nuclear localisation in the infected cell of DENV nonstructural protein 5 (NS5
s population, with effective vaccine or therapeutic currently available. A key contributor to infection is nuclear localisation in the infected cell of DENV nonstructural protein 5 (NS5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752461b26d2123e2846a384e1e0d6da4
https://doi.org/10.3390/cells8030281
https://doi.org/10.3390/cells8030281
Autor:
James C. Whisstock, David J. Kemp, James A. Irving, Charlene Willis, Sundy N.Y. Yang, Simone L. Reynolds, Katja Fischer, Tanya Ann Bashtannyk-Puhalovich, Robert N. Pike, Ashley M. Buckle, Christopher G. Langendorf, Simone A. Beckham, Ruby H. P. Law, Sheena McGowan
Publikováno v:
Journal of Molecular Biology. 390:635-645
The scabies mite (Sarcoptes scabiei) is a parasite responsible for major morbidity in disadvantaged communities and immuno-compromised patients worldwide. In addition to the physical discomfort caused by the disease, scabies infestations facilitate i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f981c38bad146ac9634d363bf0deae81
https://doi.org/10.1016/j.jmb.2009.04.082
https://doi.org/10.1016/j.jmb.2009.04.082
Autor:
Marcos R M Fontes, Sundy N.Y. Yang, David A. Jans, Jonathan M. Harris, Agnes A S Takeda, Bostjan Kobe
Publikováno v:
The Journal of Biological Chemistry
Importin-alpha is the nuclear import receptor that recognizes the classic monopartite and bipartite nuclear localization sequences (cNLSs), which contain one or two clusters of basic amino acids, respectively. Different importin-alpha paralogs in a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a248807209e480b4dbcceb4c8c4565c
https://pubmed.ncbi.nlm.nih.gov/20406804
https://pubmed.ncbi.nlm.nih.gov/20406804