DNA Polymerase Diversity Reveals Multiple Incursions of Polintons During Nematode Evolution.

Autor: Jeong DE; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Sundrani S; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Present address: Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, USA., Hall RN; Department of Bioengineering, Stanford University, Stanford, CA, USA., Krupovic M; Institut Pasteur, Université Paris Cité, Archaeal Virology Unit, Paris, France., Koonin EV; National National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA., Fire AZ; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

Publikováno v: Molecular biology and evolution [Mol Biol Evol] 2023 Dec 01; Vol. 40 (12).

Characterization of exposure-response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study.

Autor: Kotani N; Genentech, Inc., South San Francisco, CA, USA. kotani.naoki47@chugai-pharm.co.jp.; Pharmaceutical Science Department, Chugai Pharmaceutical Co., Ltd., 1-1 Nihonbashi-Muromachi 2-Chome, Chuo-ku, Tokyo, 103-8324, Japan. kotani.naoki47@chugai-pharm.co.jp., Wilkins JJ; Occams Coöperatie UA, Amstelveen, The Netherlands., Wade JR; Occams Coöperatie UA, Amstelveen, The Netherlands., Dang S; Genentech, Inc., South San Francisco, CA, USA., Sutaria DS; Genentech, Inc., South San Francisco, CA, USA., Yoshida K; Genentech, Inc., South San Francisco, CA, USA., Sundrani S; Genentech, Inc., South San Francisco, CA, USA.; Department of Bioengineering/Biomedical Computation, Stanford University, Stanford, CA, USA., Ding H; Genentech, Inc., South San Francisco, CA, USA., Garcia J; F. Hoffmann-La Roche AG, Basel, Switzerland., Hinton H; F. Hoffmann-La Roche AG, Basel, Switzerland., Sane R; Genentech, Inc., South San Francisco, CA, USA., Chanu P; Department of Clinical Pharmacology, Genentech/Roche, Lyon, France.

Publikováno v: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2022 Dec; Vol. 90 (6), pp. 511-521. Date of Electronic Publication: 2022 Oct 28.

Integrating real‐world data and machine learning: A framework to assess covariate importance in real‐world use of alternative intravenous dosing regimens for atezolizumab.

Autor: Vora, Bianca¹ (AUTHOR) vorab@gene.com, Jindal, Ashutosh¹ (AUTHOR), Velasquez, Erick¹ (AUTHOR), Lu, James¹ (AUTHOR), Wu, Benjamin¹ (AUTHOR)

Publikováno v: CTS: Clinical & Translational Science. Nov2024, Vol. 17 Issue 11, p1-13. 13p.

Development and Validation of Prognostic Models Using Radiomic Features from Pre-Treatment Positron Emission Tomography (PET) Images in Head and Neck Squamous Cell Carcinoma (HNSCC) Patients.

Autor: Philip, Mahima Merin¹ (AUTHOR) m.philip.20@abdn.ac.uk, Watts, Jessica² (AUTHOR) jessica.watts3@nhs.scot, McKiddie, Fergus² (AUTHOR) fergus.mckiddie@nhs.scot, Welch, Andy³ (AUTHOR) a.welch@abdn.ac.uk, Nath, Mintu¹ (AUTHOR) mintu.nath@abdn.ac.uk

Publikováno v: Cancers. Jun2024, Vol. 16 Issue 12, p2195. 16p.

Explainable deep learning for tumor dynamic modeling and overall survival prediction using Neural-ODE.

Autor: Laurie, Mark^1,2 (AUTHOR), Lu, James¹ (AUTHOR) lu.james@gene.com

Publikováno v: NPJ Systems Biology & Applications. 11/18/2023, Vol. 9 Issue 1, p1-11. 11p.