Xeroderma pigmentosum variant: Complementary molecular approaches to detect a 13 base pair deletion in the DNA polymerase eta gene

Autor: Hentosh, Patricia, Benjamin, Tirania, Hall, Lavinia, Leap, Shannon, Loescher, Jessica, Poyner, Elizabeth, Sundin, Tabetha, Whittle, Mary, Wilkinson, Sandra, Peffley, Dennis M.

Publikováno v: In Experimental and Molecular Pathology 2011 91(2):528-533

Therapeutic targeting of replicative immortality

Autor: Yaswen, Paul, MacKenzie, Karen L., Keith, W. Nicol, Hentosh, Patricia, Rodier, Francis, Zhu, Jiyue, Firestone, Gary L., Matheu, Ander, Carnero, Amancio, Bilsland, Alan, Sundin, Tabetha, Honoki, Kanya, Fujii, Hiromasa, Georgakilas, Alexandros G., Amedei, Amedeo, Amin, Amr, Helferich, Bill, Boosani, Chandra S., Guhan, Anur, Ciriolo, Maria Rosa, Chen, Sophie, Mohammed, Sulma I., Azmi, Asfar S., Bhakta, Dipita, Halicka, Dorota, Niccolai, Elena, Aquilano, Katia, Ashraf, S. Salman, Nowsheen, Somaira, Yang, Xujuan

Publikováno v: Seminars in cancer biology, vol 35 Suppl, iss Suppl
Yaswen, P; MacKenzie, KL; Keith, WN; Hentosh, P; Rodier, F; Zhu, J; et al.(2015). Therapeutic targeting of replicative immortality. Seminars in Cancer Biology, 35, S104-S128. doi: 10.1016/j.semcancer.2015.03.007. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/6cm6z7bq
Seminars in Cancer Biology

© 2015 The Authors. One of the hallmarks of malignant cell populations is the ability to undergo continuous proliferation. This property allows clonal lineages to acquire sequential aberrations that can fuel increasingly autonomous growth, invasiven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5ee68df6c7b5d1d26b167eca22ca463a
https://escholarship.org/uc/item/6cm6z7bq

The Dietary Isoprenoid Perillyl Alcohol Inhibits Telomerase Activity in Prostate Cancer Cells

Autor: Sundin, Tabetha

This is the first evidence that a plant-derived compound–perillyl alcohol regulates telomerase activity via the mammalian target of rapamycin (mTOR) pathway in prostate cancer cells. Telomerase–the enzyme responsible for immortalizing cells throu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8bbab69ddbd5cb8cdee2c7a3434c36ad

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